Tohoku University · 의학
Tetsuya Kodama 교수의 연구실은 주로 동물 모델을 활용한 혈관 및 림프절 전이 연구, 특히 흉부 및 하지 혈류 저류 모델을 기반으로 한 치료적 혈관신생 연구와 림프절 전이 메커니즘 규명에 초점을 맞추고 있습니다. 또한, 저강도 초음파와 마이크로버블을 이용한 세포 내 약물 전달 기술, 태양열을 활용한 수소 생산 및 석탄의 태양열 가스화 공정 등 에너지 및 나노의학 분야의 혁신적 기술 개발도 진행 중입니다. 특히 비침습적 영상 기반 동물 모델 개발과 고성능 태양열 반응기 설계를 통해 임상적 응용 가능성을 높이고자 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The detailed arterial anatomy of murine hindlimb and collateral routes deduced from the anatomy are described. Limitations on designs of ischemia models in view of anatomical variations are proposed. These observations will contribute to the development of animal studies of therapeutic angiogenesis using murine hindlimb ischemia models.
Cell permeabilization using microbubbles (MB) and low-intensity ultrasound (US) have the potential for delivering molecules into the cytoplasm. The collapsing MB and cavitation bubbles created by this collapse generate impulsive pressures that cause transient membrane permeability, allowing exogenous molecules to enter the cells. To evaluate this methodology in vitro and in vivo, we investigated the effects of low-intensity 1-MHz pulsed US and MB combined with cis-diamminedichloroplatinum (II) (
Solar CO2 gasification of coal was demonstrated under direct irradiation of the fluidized coal bed with the concentrated visible light from a solar furnace simulator in a small-scale quartz reactor. Pulverized Australian bituminous coal (the average particle size of 140 μm) was tested. The peak energy-flux density, FDpeak of the incident light beam was varied up to 1270 kW m-2. The light-to-chemical (enthalpy) energy conversion via the solar gasification increased with increasing the energy-flux
A two-step thermochemical water splitting cycle using nonstoichiometric cerium oxide is a promising solar thermochemical hydrogen production process. One of the present authors has developed new solar reactors using “internally circulating fluidized beds” with cerium oxide particles for the high-temperature cycle. These solar reactors need to be combined with a beam-down solar concentrating system. Niigata University, University of Miyazaki, and Mitaka Kohki Co. Ltd. recently started an R&D join
