Hokkaido University · 의학
Shimizu 교수의 연구실은 뼈의 미세구조와 관절 질환의 생체역학적 기전을 중심으로 한 고해상도 허브-고해상도 CT(HR-pQCT)를 활용한 류마티스성 관절염 및 골다공로시스의 조기 진단 및 치료 반응 평가를 연구하고 있습니다. 특히, 항-TNFα 치료가 뼈 침식 진행을 억제하는 메커니즘을 3개월 이내의 단기 평가로 규명하며, 관절염과 골다공로시스의 연관성, 특히 하부연골 뼈의 취약성과 부식성 골절(SIF)의 역할을 밝혀내고 있습니다. 또한 수술 영상 분석을 위한 수술도구 및 손 움직임 기반 도구 분류 기술 개발을 통해 외과 수술의 정밀도 향상에도 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Level II, prospective trial.
Using HR-pQCT, our data suggest that anti-TNFα treatment prevents erosion progression and deterioration of bone microarchitecture within the first 3 months of treatment, one patient not responding to treatment, had significant progression of bone erosions within this short time period. Patients with low disease activity scores (<3.2) can have continuous HR-pQCT-detectable progression of erosive disease with MTX treatment only. HR-pQCT can be a sensitive, powerful tool to quantify bone changes an
The increased incidence of osteoarthritis (OA), particularly knee and hip OA, and osteoporosis (OP), owing to population aging, have escalated the medical expense burden. Osteoarthritis is more prevalent in older women, and the involvement of subchondral bone fragility spotlights its association with OP. Notably, subchondral insufficiency fracture (SIF) may represent a more pronounced condition of OA pathophysiology. This review summarizes the relationship between OA and OP, incorporating recent
Our data should be useful for analyzing pitching activity and clarifying the pathology of shoulder disorders associated with throwing.
Because of the adverse consequences of abnormal knee kinetics on anterior laxity after ACLR, efforts to improve knee movement patterns should be initiated.
Detecting surgical tools is an essential task for the analysis and evaluation of surgical videos. However, in open surgery such as plastic surgery, it is difficult to detect them because there are surgical tools with similar shapes, such as scissors and needle holders. Unlike endoscopic surgery, the tips of the tools are often hidden in the operating field and are not captured clearly due to low camera resolution, whereas the movements of the tools and hands can be captured. As a result that the
