Kyushu University · 의학
Toshiharu Ninomiya 교수의 연구실은 당뇨병과 만성 신장질환, 고혈압, 뇌질환 간의 복합적 연관성에 중점을 두고 있으며, 특히 당뇨병 환자에서 단백뇨와 혈액형광검사로 평가되는 신기능 저하가 심혈관 및 신장 합병증에 미치는 독립적 영향을 규명하고자 합니다. 또한 고령층에서 고혈압이 혈관성 치매와 알츠하이머병 발생에 미치는 영향을 장기적 관찰을 통해 분석하고 있으며, 식이요법(예: 지중해 식단)이 혈관질환 예방에 미치는 영향에 대해서도 철저한 임상 연구를 수행하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
There are limited data regarding whether albuminuria and reduced estimated GFR (eGFR) are separate and independent risk factors for cardiovascular and renal events among individuals with type 2 diabetes. The Action in Diabetes and Vascular disease: preterAx and diamicroN-MR Controlled Evaluation (ADVANCE) study examined the effects of routine BP lowering on adverse outcomes in type 2 diabetes. We investigated the effects of urinary albumin-to-creatinine ratio (UACR) and eGFR on the risk for card
Diabetes mellitus and cancer are diseases of epidemic proportions across the globe. These diseases are influenced by many factors, both genetic and environmental. A possible association between diabetes and cancer risk has long been speculated. Increased incidence of several cancers has been observed in diabetes patients, notably pancreatic, hepatic, colorectal, breast, urinary tract, and endometrial cancers. In contrast, a decreased incidence of prostate cancer is observed in diabetes patients,
The associations between blood pressure and dementia have been inconclusive. We followed up a total of 668 community-dwelling Japanese individuals without dementia, aged 65 to 79 years, for 17 years and examined the associations of late-life and midlife hypertension with the risk of vascular dementia and Alzheimer disease using the Cox proportional hazards model. During the follow-up, 76 subjects experienced vascular dementia and 123 developed Alzheimer disease. The age- and sex-adjusted inciden
The Mediterranean diet may protect against vascular disease. However, both the quantity and quality of the available evidence is limited and highly variable. Results must be interpreted with caution.