Woo Joo Kim
고려대학교 의과대학 · 의학
우주 김 교수의 연구실은 감염병, 항생제 내성 미생물, 염증 반응 및 세포외기질 변화와 관련된 효소(MMPs)의 역할을 중심으로 병원성 미생물의 전파 메커니즘과 숙주의 면역 반응을 분석하고 있습니다. 특히 다제내성 박테리아인 벤코마이신 내성 엔테로코커스(VRE)의 유통 및 내성 유전자 전이 메커니즘에 대한 장기적 역학 연구를 수행하고 있으며, 인플루엔자 감염의 중증도와 관련된 기저질환의 영향을 규명하는 임상 역학 연구도 진행 중입니다. 이는 감염병의 예방 및 치료 전략 수립에 기여할 수 있는 기초적이고 임상적 통찰을 제공합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Matrix metalloproteinases (MMPs) are involved in extracellular matrix remodeling through the degradation of extracellular matrix components and are also involved in the inflammatory response by regulating the pro-inflammatory cytokines TNF-α and IL-1β. Dysregulation in the inflammatory response and changes in the extracellular matrix by MMPs are related to the development of various diseases including lung and cardiovascular diseases. Therefore, numerous studies have been conducted to understand
Phylogenetic analysis was conducted on 9 kDa non-specific lipid transfer protein (nsLTP) genes from nine plant species. Each of the five classified types in angiosperms exhibited eight conserved cysteine patterns. The most abundant nsLTP genes fell into the type I category, which was particularly enriched in a grass-specific lineage of clade I.1. Six pairs of tandem copies of nsLTP genes on the distal region of rice chromosomes 11 and 12 were well-preserved under concerted evolution, which was n
The contributions of clonal spread, transfer of genetic elements, and introduction of new strains to the establishment of endemicity of vancomycin-resistant enterococci (VRE) were determined. The study took place at one hospital between 1990, when VRE were first detected, and 1996, when endemicity had become established. Isolates from 183 patients were categorized into 24 strain types by pulsed-field gel electrophoresis; the resistance genotype was determined by polymerase chain reaction. Betwee
The proportion of males to females and elderly population were significantly higher for influenza A (H3N2) patients group compared with influenza B group. Hypertension, diabetes, chronic lung diseases, cardiovascular disorders, and neuromuscular diseases were independently associated with hospitalization due to influenza. Physicians should assess and treat the underlying comorbid conditions as well as influenza viral infections for the appropriate management of patients with influenza.
Nam, Ki Y. MD; Kim, Woo J. MD; Jo, Young J. MD; Kim, Jung Y. MDEditor(s): Williams, George A. Author Information
