The University of Tokyo · 환경과학
이 연구실은 기후 변화와 환경 요인의 건강 영향을 중심으로 한 환경보건 연구를 수행하고 있습니다. 특히 기후 변화와 관련된 온도, 대기오염 등 환경 요소가 정신건강(자살률)과 감염병(말라리아)에 미치는 영향을 시간적·공간적 분석을 바탕으로 규명하고 있습니다. 또한 수질 및 수온의 열역학적 특성에 대한 수리모델링을 통해 수질환경의 변화를 예측하는 데에도 전문성을 기르고 있습니다. 이와 같은 연구들은 기후위기 대응을 위한 정책적 근거를 제공하는 데 기여합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Twenty-five years ago the first small molecule inhibitors of Hsp90 were identified. In the intervening years there has been dramatic progress in basic scientific understanding of the Hsp90 chaperone machinery and in the role of Hsp90 in malignancy. The first-in-class Hsp90 inhibitor 17-AAG entered into Phase I clinical trials in 1999. There are now 13 Hsp90 inhibitors in clinical trial, representing multiple drug classes, and hundreds of patients have been treated in adult oncology and pediatric
Our findings showed that the risk of suicide increased with increasing ambient temperature in many countries, but to varying extents and not necessarily linearly. This temperature-suicide association should be interpreted cautiously, and further evidence of the relationship and modifying factors is needed. https://doi.org/10.1289/EHP4898.
Kim Y, Kim H, Honda Y, Guo YL, Chen BY, Woo JM, Ebi KL. 2016. Suicide and ambient temperature in East Asian countries: a time-stratified case-crossover analysis. Environ Health Perspect 124:75-80; http://dx.doi.org/10.1289/ehp.1409392.
Our findings suggest that higher levels of air pollution may be associated with suicide, and further research is merited to understand the underlying mechanisms. https://doi.org/10.1289/EHP2223.
Although there have been enormous demands and efforts to develop an early warning system for malaria, no sustainable system has remained. Well-organized malaria surveillance and high-quality climate forecasts are required to sustain a malaria early warning system in conjunction with an effective malaria prediction model. We aimed to develop a weather-based malaria prediction model using a weekly time-series data including temperature, precipitation, and malaria cases from 1998 to 2015 in Vhembe,
Abstract The temporal and spatial distribution of water temperature was surveyed and simulated in a deep warm monomictic reservoir (Lake Soyang, Korea). The great depth (maximum depth 118 m) and wind-sheltered dendritic shape caused stable thermal stratification in summer. Turbid storm runoff during the summer monsoon formed a 20–40 m intermediate layer distinct from the clearer epilimnion and hypolimnion. The temperature distribution and movements of the density current were simulated by using
Despite impressive economic growth and increasing prosperity, cities in Mexico do not seem to have fully captured the benefits of urban agglomeration, in part because of rapid and uncoordinated urban growth. Recent expansion of many Mexican cities has been distant, disconnected, and dispersed, driven mainly by large single-use housing developments on the outskirts of cities. The lack of a coordinated approach to urban development has hindered the ability of cities in Mexico to boost economic gro
