Kyoto University · 의학
유 우네노 교수의 연구실은 고령 환자 대상 암 환자의 종합적 돌봄 필요성과 치료 예후 예측 모델 개발에 초점을 맞추고 있습니다. 특히 고령 암 환자의 신체적·정서적·사회적 지원 필요성과 함께, 화학요법 중 열성 중성구감소증 위험 환자에 대한 조기 항진균 치료 전략에 대한 연구도 진행 중입니다. 또한 실생활 데이터 기반 시간열 분석을 활용한 정밀의료 모델 개발과 희귀 신경질환인 종양유발성 뇌병증의 임상 사례 분석을 통해 종합적인 암 관리 전략을 모색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Cancer poses numerous challenges for the elderly and affects various aspects of their lives, including economic, family, psychological, social, and physical well-being. This study aimed to investigate the supportive care needs of the elderly with cancer. In this descriptive-analytical research, 248 elderly individuals (144 men and 104 women) with a mean age of 67.17 ± 6.94 years, who were diagnosed with cancer, were selected from the Seirei Mikatahara General Hospital, Japan, in 2023 using a non
By applying time-series real-world big data, we successfully developed a set of six adaptable prognosis prediction models for patients with cancer receiving chemotherapy.
For people with cancer who are at high-risk of febrile neutropenia, pre-emptive antifungal therapy may reduce the duration and rate of use of antifungal agents compared to empirical therapy, without increasing over-all and IFD-related mortality; but the evidence regarding invasive fungal infection detection and adverse events was inconsistent and uncertain.
UMIN000048554.
Cancer can cause many problems in all family, economic, social, psychological, and physical dimensions for the elderly. The present research was conducted to examine the supportive care requirements of the elderly with cancer. In this descriptive-analytical study, a total of 248 elderly (144 men and 104 women) with an average age of 67.17 ± 6.94 years with cancer were referred to Seirei Mikatahara General Hospital, Japan, using non-probability and available sampling in 2023. The data coll
Paraneoplastic neurological syndromes (PNSs) are rare nervous system dysfunctions in cancer patients, which are primarily observed with small-cell lung cancer, gynecological cancer, and thymoma. We herein present an uncommon case of PNS in an anti-Hu antibody-positive patient with human epidermal growth factor receptor (HER)-2-positive gastric cancer (GC), who developed limbic encephalitis and a worsening cognitive function. Trastuzumab-combined chemotherapy was initiated and appeared to be part
This survey highlighted a considerable number of IOP indicators met, particularly in DCHs probably due to the government policy. Further efforts are needed to address the serious research/educational gaps.
UMIN000048554, registered 2 August 2022.
The findings of this study reveal the need for further effort to enrich the mentorship and support systems for junior physicians delivering end-of-life care.
Physicians' attitudes toward end-of-life care correlate more strongly with nonmodifiable factors, but attitudes can be meaningfully improved via mentoring by senior physicians. Future studies are warranted to determine the effective interventions to foster positive attitudes among physicians involved in end-of-life care.
Prognosis prediction is a clinically relevant issue to facilitate optimal decision-making for both physicians and patients with cancer. Many previous studies revealed that prognosis prediction based on the physician's intuition and/or clinical experience is inaccurate and often optimistic, which means that there is a tendency to overestimate patient survival in daily clinical practice. In recent decades, many efforts have been made to develop prognosis prediction models which aid physicians to m
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the relative efficacy, safety, and impact on clinical resource use of pre‐emptive versus empirical antifungal therapy in people with cancer who have febrile neutropenia.
