Hokkaido University · 의학
Yuma Ebihara 교수의 연구실은 위식도암의 분자 기전과 치료 전략 개발에 초점을 맞추고 있으며, 특히 에스ophageal squamous cell carcinoma(ESCC)에서 E2F-1과 DARPP-32 등의 전사인자 및 신호전달 단백질의 역할을 분석하고 있습니다. 로봇 수술 기술의 임상적 적용 가능성도 탐색하며, 텔레로봇 수술을 통한 원격 외과 수술의 실현 가능성을 실험적으로 검증하고 있습니다. 이는 기초 생물학적 메커니즘과 임상 응용을 연결하는 다학제적 접근을 특징으로 합니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Functional end-to-end esophagojejunostomy in TLTG is safe and feasible.
The transcription factor E2F-1, a downstream regulator of the p16-cyclinD-Rb pathway, is required for cell cycle progression. Evidence shows that overexpression of E2F-1 can either promote or inhibit the development of tumors, depending on tissue or experimental conditions. However, the clinical impact of E2F-1 expression on esophageal squamous cell carcinoma (ESCC) remains unknown. To analyze E2F-1 expression in ESCC, we investigated the immunoreactivity of E2F-1 and its correlation with clinic
This is the first report to correlate DARPP-32 immunoreactivity (dopamine and cAMP-regulated phosphoprotein, M(r) 32 000) to clinicopathological status in human cancer. DARPP-32 is recognised as a neuronal protein. A recent study demonstrated that DARPP-32, and a truncated isoform t-DARPP, are overexpressed in gastric carcinoma during the process of carcinogenesis. The biological function of DARPP-32, however, is still unclear. The purpose of this study was to clarify the roles of DARPP-32 and t
The purpose of this study is to evaluate the performance of tele-robotic distal gastrectomy (tele-RDG) with lymph node dissection (LND) using a novel Japanese-made surgical robot hinotori™ (Medicaroid, Kobe, Japan) in a cadaver with a presumptive gastric cancer. The Cadaveric Anatomy and Surgical Training Laboratory (CAST-Lab.) at Hokkaido University and Kushiro City General Hospital (KCGH) are connected by a guaranteed type line (1 Gbps), and the distance between the two facilities is 250 km. A
