东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Yaozhong Zhang's research lab specializes in computational biology and bioinformatics, focusing on developing advanced machine learning and deep learning methods for genomic data analysis. Key research directions include nanopore sequencing basecalling and methylation detection using transformer-based models, phage-host interaction prediction through contrastive learning and sequence embedding, and the application of neural networks to model complex biological processes such as epithelial-mesenchymal transition in cancer. The lab emphasizes innovative algorithm design for high-accuracy, efficient biological sequence analysis.
Professor Shuntaro Takeda's research lab specializes in photonic quantum computing, focusing on scalable and fault-tolerant quantum information processing using continuous-variable (CV) optics. The lab pioneers hybrid quantum systems that unify discrete-variable and continuous-variable approaches, enabling deterministic quantum gates and universal quantum computation. Key research directions include time-domain multiplexing, loop-based architectures, and measurement-induced quantum gates for large-scale integration. The lab also develops advanced techniques for characterizing and manipulating time-bin qubits and achieving high-fidelity quantum teleportation with experimental robustness.
Professor Takeo Hoshi's research lab specializes in corporate finance, financial intermediation, and the role of financial institutions in corporate investment and restructuring. The lab investigates how information asymmetries, incentive problems, and institutional structures—particularly in the Japanese context—affect corporate financing decisions, capital allocation, and macroeconomic performance. A central focus is on the impact of bank-firm relationships, especially within keiretsu networks, and how financial deregulation and systemic inefficiencies influence firm behavior and economic stagnation.
Professor Yu Takahashi's research lab focuses on cellular and molecular mechanisms underlying metabolic regulation, with a central emphasis on lipid metabolism, adipogenesis, and stem cell differentiation. The lab investigates key regulators such as PPARγ, SREBP-1, and TRB3 in the context of lipid droplet formation, insulin sensitivity, and metabolic homeostasis using human iPSC-derived organoids and primary cell models. A major research direction involves developing advanced 3D culture systems to model human intestinal and hepatic physiology for toxicological and regenerative medicine applications. The lab also explores the genetic and signaling networks governing somitogenesis and cell fate determination in vertebrate development.
Professor Qiang Guo's research lab specializes in climate-hydrology interactions, with a focus on improving the accuracy of climate model outputs for hydrological impact assessments through advanced bias correction techniques. The lab investigates the effects of climate change and human activities—particularly agricultural irrigation—on urban and regional climate extremes, including humid heat stress and extreme precipitation events. Using high-resolution climate modeling, reanalysis data, and interdisciplinary approaches combining climatology, hydrology, and public health, the lab aims to enhance heat-health warning systems and climate resilience strategies. A unique aspect of the lab’s work includes the development of physically based simulation methods for artistic ink rendering, reflecting an innovative fusion of computational science and cultural heritage.
Professor Takeshi Nagamatsu's research lab focuses on the immunological and vascular mechanisms underlying fetal-maternal tolerance and placental development. Key research directions include the regulation of angiogenic factors such as VEGF and sFlt-1 under varying oxygen tensions, the role of decidual immune cells—particularly macrophages and T cells—in maintaining pregnancy, and the signaling functions of bioactive lipids like LPA and S1P in reproductive physiology. The lab also investigates soluble biomarkers, such as the sFlt-1/PlGF ratio, for the early diagnosis of preeclampsia, contributing to clinical translation in maternal-fetal medicine.
Professor Simon Wallis's research focuses on high-pressure and ultrahigh-pressure metamorphism, with an emphasis on the tectonic processes that transport deep-earth materials to the surface. His work explores the geodynamic evolution of convergent margins, particularly in regions like the Sulu and Sanbagawa terranes, where metamorphic belts preserve critical records of subduction and exhumation. He integrates petrology, geochronology, and thermobarometry to reconstruct P–T paths and understand the role of partial melting and fluid activity in metamorphic systems. His studies also examine the structural and chemical evolution of eclogite and granitoid rocks under extreme conditions, contributing to broader models of continental collision and orogenic belt formation.
Professor K. Wimmer's research lab specializes in experimental nuclear physics, focusing on the structure and spectroscopy of exotic, neutron- and proton-rich nuclei far from stability. The lab investigates shell evolution, shape coexistence, and isospin symmetry breaking using advanced transfer reactions and inelastic scattering with radioactive ion beams. Key research directions include the study of nuclear collectivity, single-particle excitations, and the limits of nuclear stability through experiments at facilities like REX-ISOLDE. The lab combines innovative inverse-kinematics techniques with theoretical modeling to probe fundamental nuclear forces and collectivity in light to medium-mass nuclei.
Professor Zhenzhi Ying's research lab specializes in intelligent manufacturing and human-machine interaction, focusing on advanced signal processing and machine learning for real-time monitoring and control in precision machining and surgical robotics. The lab develops data-driven models that integrate acoustic, force, and biological signals—such as EMG and neural spike trains—to enhance tool life prediction, cutting state recognition, and prosthetic control. Key research directions include condition monitoring in hard-to-machine materials like titanium alloys, autonomous penetration detection in spinal surgery, and neural decoding for dexterous prosthetic hand control.
Professor Jonathan Woodward's research lab specializes in the fundamental mechanisms of radical pair dynamics and their influence on chemical and biological processes, particularly through the lens of electron spin and magnetic field effects. The lab investigates how weak magnetic fields—ranging from Earth's field to clinical-strength fields—affect electron transfer reactions in enzymes and biological systems, with a focus on flavin-based photochemistry and the radical pair mechanism. A key direction involves developing and applying advanced spectroscopic and imaging techniques to detect and quantify these magnetic field effects at the single-cell level. The lab also explores enzyme immobilization strategies to enhance biocatalyst performance and stability, particularly in the context of cellulose degradation and metabolic engineering.
Professor Kenji Fujimoto's research lab specializes in nonlinear control theory, with a strong focus on Hamiltonian systems, balanced realization, and model order reduction for both continuous-time and discrete-time systems. The lab develops advanced analytical frameworks based on Hankel operators and singular value decomposition to characterize system behavior, stability, and controllability/observability in nonlinear dynamics. A key direction involves creating robust control methodologies—such as iterative learning control and passivity-based sliding mode control—by leveraging the intrinsic geometric and energy-based structures of mechanical and electromechanical systems. The lab also applies these theoretical advances to biomedical engineering, notably in non-invasive liver fibrosis assessment using ultrasound elastography.
Professor Wataru Yamazaki's research lab specializes in the development of advanced molecular diagnostics and computational modeling techniques for biomedical and engineering applications. The lab focuses on creating rapid, sensitive, and specific detection methods—particularly loop-mediated isothermal amplification (LAMP) and multiplex PCR—for foodborne and waterborne pathogens such as *Vibrio parahaemolyticus*, *V. cholerae*, and *Campylobacter* species. In parallel, the lab develops high-fidelity surrogate modeling techniques using kriging with gradient and Hessian enhancements for efficient design optimization and uncertainty quantification in aerodynamic and fluid dynamic systems. These interdisciplinary efforts bridge microbiology, molecular diagnostics, and computational engineering to address public health and engineering challenges.
Professor Takaya Ogawa's research lab focuses on advancing sustainable energy technologies through the fundamental understanding and design of functional materials for energy conversion and storage. Key research directions include proton conduction mechanisms in hybrid and inorganic electrolytes, with an emphasis on developing materials for efficient fuel cells and water electrolyzers under low-humidity conditions. The lab combines computational materials science, advanced spectroscopy, and theoretical calculations to explore novel ion transport mechanisms—such as the packed-acid mechanism—and to design high-performance catalysts for ammonia synthesis and hydrogen production. Their work bridges materials chemistry, electrochemistry, and computational modeling to address critical challenges in clean energy applications.
Professor Zhicheng Yuan's research lab specializes in interdisciplinary studies at the intersection of biomedical engineering, fluid dynamics, and autonomous systems. The lab investigates molecular mechanisms of acute lung injury and acute respiratory distress syndrome (ARDS), focusing on receptors like RAGE and formyl peptide receptor-1 in lung fluid regulation and inflammation. It also explores droplet dynamics on patterned surfaces, particularly wetting transitions and surface design for enhanced hydrophobicity. Additionally, the lab develops advanced control strategies for multi-vehicle systems in uncertain environments, emphasizing robust estimation and finite-time control for autonomous navigation and field source seeking.
Professor Hiroaki Konishi's research lab specializes in advanced energy storage materials and sustainable chemical processes. The lab focuses on developing next-generation fluoride shuttle batteries (FSBs) using metal fluorides like BiF₃ as high-capacity catholyte materials, with a strong emphasis on optimizing electrolyte systems through anion acceptors such as triphenylboroxine to enhance solubility and electrochemical performance. In parallel, the lab investigates regioselective chemical interesterification of vegetable oils to produce high-stability margarine basestocks, demonstrating a dual focus on clean energy technologies and green chemistry. The integration of nanomaterial design, electrochemistry, and catalytic processes defines the lab’s interdisciplinary approach.
Professor Sukyoung Hwang's research lab specializes in the microstructure-property relationships in advanced metallic materials, with a primary focus on high-Mn austenitic steels. The lab investigates deformation mechanisms such as Lüders banding, Portevin-Le Chatelier (PLC) effects, and strain localization using advanced in-situ characterization techniques like digital image correlation (DIC), synchrotron XRD, and electron microscopy. A key research direction involves understanding how grain refinement and microstructural evolution influence plasticity and deformation heterogeneity in structural alloys. The lab also explores plasma-polymerized thin film growth kinetics, extending its expertise into functional thin films for potential applications in coatings and surface engineering.
Professor Yufan Shen's research lab specializes in the epitaxial growth and fundamental characterization of complex oxide thin films and 2D membranes, with a focus on manipulating their electronic, magnetic, and ferroelectric properties through strain engineering and interface control. The lab explores metastable phases in hafnia- and zirconia-based oxides, inverse spinel ferrimagnets like NiCo₂O₄, and protonic gating in complex perovskites to enable next-generation spintronic and nanoelectronic devices. Key research directions include the stabilization of non-bulk ferroelectric phases, half-metallic behavior in spinels, and the development of functional 2D oxide membranes for scalable nanodevices.
Professor Koichi Hosomi's research lab specializes in non-invasive brain stimulation therapies, particularly repetitive transcranial magnetic stimulation (rTMS), for neurological disorders. The lab focuses on understanding and treating chronic neuropathic pain, especially central post-stroke pain (CPSP), and investigating the neurophysiological mechanisms underlying rTMS-induced changes in cortical excitability. Their work also explores the role of white matter integrity and network hyperexcitability in spinal cord injury-related pain, using advanced neuroimaging techniques. The lab integrates clinical trials with neurophysiological and neuroimaging assessments to optimize rTMS protocols for pain relief and motor recovery in stroke and other neurological conditions.
Professor Ryu Kanzaki's research lab focuses on advancing cancer therapeutics by investigating the tumor microenvironment, particularly the role of cancer-associated fibroblasts (CAFs) in tumor progression and treatment response. The lab employs single-cell analysis technologies to dissect CAF heterogeneity and understand how stromal components like Axl/Gas6 signaling influence chemotherapy resistance in non-small cell lung cancer. Additionally, the lab explores surgical outcomes and diagnostic imaging strategies for metastatic cancers, including renal cell carcinoma and non-small cell lung cancer, with an emphasis on pulmonary metastasectomy and FDG-PET/CT applications. Their work bridges translational oncology, molecular pathology, and minimally invasive surgical techniques.
Professor Yixun Wang's research lab specializes in the fatigue assessment and structural integrity of welded steel joints, with a strong focus on improving the accuracy of stress concentration factor (SCF) calculations through advanced geometric modeling. The lab develops parametric formulae based on spline-based weld models to better represent real weld geometries, enhancing the reliability of fatigue life predictions. Key research directions include the application of finite element analysis (FEA), digital image correlation (DIC), and X-ray diffraction (XRD) to evaluate local strain, residual stress, and fracture behavior in various welding processes such as linear friction welding (LFW) and friction stir welding (FSW). The lab also investigates innovative repair techniques and material behavior in high-phosphorus and weathering steels to address challenges in crack prevention and joint performance.
