Hyung Jun Kim
연세대학교 기계공학과 · 공학
김형준 교수의 연구실은 구강악성종양 및 치료 관련 질환의 조기 진단과 치료 전략 개발에 초점을 맞추고 있습니다. 특히 흉부·구강영상 영상 분석을 위한 딥러닝 기반 진단 알고리즘 개발과 치료 후 생체 내부 적응 메커니즘(예: 충치 복원물의 내적 밀착성)에 대한 비파괴적 분석 기술을 응용하고 있습니다. 또한 항암제의 귀이명성 독성과 관련된 세포 대사 조절 메커니즘, 특히 NAD+/SIRT1 경로의 역할을 규명하는 분야에서도 활발한 연구를 수행하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Patients with odontogenic cysts and tumors may have to undergo serious surgery unless the lesion is properly detected at the early stage. The purpose of this study is to evaluate the diagnostic performance of the real-time object detecting deep convolutional neural network You Only Look Once (YOLO) v2-a deep learning algorithm that can both detect and classify an object at the same time-on panoramic radiographs. In this study, 1602 lesions on panoramic radiographs taken from 2010 to 2019 at Yons
It was recently reported that prophylaxis against infectious hematopoietic necrosis virus (IHNV) in fish was induced by pre-exposure to the infectious pancreatic necrosis virus (IPNV). Here the establishment of IHNV immunity in rainbow trout Oncorhynchus mykiss was investigated by IHNV challenge following non-lethal pre-infection with IPNV. Also, synthetic double-stranded RNA polyinosinic polycytidylic acid, Poly(I:C), an inducer for interferon (IFN), was evaluated as a substitute for IPNV induc
In the present study, the internal adaptation of dentin-composite interfaces with various resin composite materials under conditions of thermomechanical loading was analyzed nondestructively using micro-computed tomography (micro-CT), and these results were compared with analyses of microgaps after sectioning. Additionally, the correlation of internal adaptation with polymerization shrinkage strain and stress was evaluated. Four nonflowable resins, Gradia Direct (GD), Filtek P90 (P9), Filtek Z35
Cisplatin (cis-diaminedichloroplatinum-II) is an extensively used chemotherapeutic agent, and one of its most adverse effects is ototoxicity. A number of studies have demonstrated that these effects are related to oxidative stress and DNA damage. However, the precise mechanism underlying cisplatin-associated ototoxicity is still unclear. The cofactor nicotinamide adenine dinucleotide (NAD(+)) has emerged as a key regulator of cellular energy metabolism and homeostasis. Here, we demonstrate for t