Hyung Woo Kim
연세대학교 의과대학 · 의학
Hyung Woo Kim 교수의 연구실은 만성질환, 특히 만성신장질환과 췌장암 등 악성 종양의 진행 양상과 예후를 중심으로 한 임상 역학 및 생물학적 마커 연구를 수행하고 있습니다. 저소변 칼륨 배설과 신기능 악화의 연관성, 췌장암에서 IL-6·IL-8의 예측적 역할, 간전이의 형태에 따른 생존 예측 등 정밀의료 기반의 개인화 치료 전략 개발에 초점을 맞추고 있습니다. 또한 혈액 투석 환자의 투석 효도를 예측하기 위한 머신러닝 기반 분석도 진행 중이며, 수술 후 담석 형성 위험 요인 분석을 통해 장기적 건강 관리 전략을 모색하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Low urinary potassium excretion is associated with progression of CKD.
Several reports showed that interleukin-6 (IL-6) or -8 (IL-8) might be useful inflammatory biomarkers for pancreatic ductal adenocarcinoma (PDAC), although these clinical impact is still open to debate. The aim of this study was to elucidate whether serum levels of IL-6 and IL-8 at diagnosis could predict the tumor progression pattern of PDAC, especially in extensive hepatic metastasis.According to the tumor burden of hepatic metastasis at the last follow-up, tumor progression pattern was define
Abstract A heavy rainfall event induced by mesoscale convective systems (MCSs) occurred over the middle Korean Peninsula from 25 to 27 July 1996. This heavy rainfall caused a large loss of life and property damage as a result of flash floods and landslides. An observational study was conducted using Weather Surveillance Radar-1988 Doppler (WSR-88D) data from 0930 UTC 26 July to 0303 UTC 27 July 1996. Dominant synoptic features in this case had many similarities to those in previous studies, such
Dialysis adequacy is an important survival indicator in patients with chronic hemodialysis. However, there are inconveniences and disadvantages to measuring dialysis adequacy by blood samples. This study used machine learning models to predict dialysis adequacy in chronic hemodialysis patients using repeatedly measured data during hemodialysis. This study included 1333 hemodialysis sessions corresponding to the monthly examination dates of 61 patients. Patient demographics and clinical parameter
Previous studies reported increased incidence of gallstone formation after gastrectomy. However, there were few reports about factors other than surgical technique. The purpose of this study is to investigate the spectrum of risk factors of gallstone formation after gastrectomy. From June 2003 to December 2008, 1480 patients who underwent gastrectomy due to gastric cancer but had no gallstones before surgery were identified. Electronic medical records were retrospectively reviewed. Gallstones we
Few studies have evaluated the presence of hepatic or peritoneal metastasis as a prognostic factor in patients with metastatic pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the prognostic value of the initial metastatic, extrahepatic, or hepatic site in patients with metastatic PDAC. Between January 2007 and December 2013, the medical records of 343 patients with metastatic PDAC treated at Seoul National University Bundang Hospital were retrospectively reviewed. Patients
Vitamin C is an essential water-soluble nutrient which primarily exerts its effect on host defense mechanisms and immune homeostasis, but the mechanism related to immune-potentiation is poorly understood. Since dendritic cells (DCs) are known as a potent antigen presenting cell (APC) that could enhance the antigen specific immune responses, we investigate the effects of vitamin C on activation of DCs and its related mechanism by using dendritic cell lines, DC-1. First, we found that there was no