Kyoto University · 의학
Kazuhiro Mori 교수의 연구실은 심장 질환의 조기 진단과 메커니즘 규명을 위한 심장초음파 영상 기반 연구와 함께, 혈액세포 생성 조절 메커니즘에 대한 분자생물학적 연구를 병행하고 있습니다. 특히 심장의 미세한 기능 이상을 감지할 수 있는 심장장력 영상 기술과, 에리스로포이에틴(EPO) 수용체를 통한 세포 증식 및 분화 조절 메커니즘을 규명하고 있습니다. 또한 고성능 전지 기술 개발을 위한 고체 전해질 내 이온 이동 메커니즘 연구도 진행 중이며, 중성자 산란 및 구조 분석 기법을 활용해 리튬 및 플루오르화 이온의 이동 경로를 정밀하게 규명하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
The two ventricles differ in their normal PWDT echocardiographic values and in the parameter change after birth during the early neonatal period, which may reflect differences in ventricular adaptation after birth.
Interaction between erythropoietin (EPO) and its membrane receptor induces the proliferation and differentiation of erythroid progenitors. EPO has been shown to activate the JAK2-STAT5 pathway in various hematopoietic cell lines, although the physiological role of this pathway is unclear. We have previously shown that epidermal growth factor activates a chimeric receptor bearing the extracellular domain of the epidermal growth factor receptor linked to the cytoplasmic domain of the EPO receptor,
Myocardial strain imaging in DMD patients was characterized by decreased peak systolic strain of the posterior wall despite normal standard echocardiographic findings. Strain measurement might be useful for early detection of subtle regional myocardial dysfunction.
Designing the next generation of lithium ion batteries requires fundamental information that surprisingly often is still unknown---for example, details of how ions actually move through a working device. The authors use state-of-the-art quasielastic neutron scattering to directly monitor the fast diffusion of Li${}^{+}$ in a promising solid electrolyte. Here the ions migrate between stable regions within a jump length $<l>$ = 4.3 \AA{} along conduction pathways that thread stacks of tetrah
We isolated the full length provirus of human T cell leukaemia virus type I (HTLV-I) from MT-2, a lymphoid cell line producing HTLV-I. In three non-lymphoid cell lines (COS7, human osteosarcoma HOS cells, and HeLa) this provirus expressed a trans-acting activity after co-transfection with a recombinant plasmid carrying a bacterial chloramphenicol acetyltransferase gene under the control of a long terminal repeat of HTLV-I provirus. The trans-acting protein p40 was detected by immunoprecipitation
All-solid-state fluoride shuttle batteries (FSBs) have the potential to become the next generation of rechargeable batteries. However, there are gaps in the fundamentals of developing all-solid-state FSBs. For example, the mechanism by which the F– ions travel through a working device is not yet fully understood. In this work, we use a cutting-edge neutron diffractometer and a suite of analysis programs to perform Rietveld refinements. We employ the maximum entropy method to experimentally deter