東京大学 · Medicine
키요시 하세가와 교수의 연구실은 간세포암종(HCC)의 수술적 치료 전략과 임상 지침 개발에 초점을 맞추고 있습니다. 특히 해부학적 절제술이 비해부학적 절제술보다 더 유리한 결과를 보인다는 연구를 통해 정확한 수술 기법의 중요성을 입증하고 있으며, 일본 간학회가 제작한 간세포암종 임상지침의 최신 버전 개정에도 기여했습니다. 또한 바이러스성 간염, 특히 B형 간염 바이러스의 변이가 급성 간부전과 연관되는 메커니즘에 대해서도 분자생물학적 접근을 통해 규명하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Anatomic resection for a single HCC yields more favorable results rather than nonanatomic resection.
The fifth version of the Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence-based medicine and partly to the Grading of Recommendations Assessment, Development and Evaluation system, which was published in October 2021 in Japanese. In addition to surveillance-diagnostic and treatment algorithms, a new algorithm for systemic therapy has been created, as multiple drugs for hepatocellular carcinoma can b
Hepatitis B virus (HBV) mutants unable to synthesize HBV e antigen have been described in association with fulminant hepatitis. We have cloned and sequenced the entire viral genome of an HBV strain associated with an epidemic of fulminant hepatitis. This strain contained, in addition to two G-to-A mutations in the precore region (nucleotides 1898 and 1901), numerous other mutations in conserved nucleotide positions resulting in significant amino acid substitutions in HBV gene products. We introd
UMIN Clinical Trials Registry C000000013.
