Kyu Ha Huh
연세대학교 의과대학 신경외과학교실 · 의학
Kyu Ha Huh 교수의 연구실은 신장 이식에서의 기증자 교환 프로그램 최적화와 혈액형 O 수혜자에 대한 한계를 고려한 이식 전 위험 평가 기법 개발에 주력하고 있습니다. 또한, 간질 수술 전 평가 시 뇌전기 활동과 인지 기능 간의 상관관계를 분석하는 뇌전파 연구를 통해 신경기능 평가의 정밀도를 높이고자 합니다. 특히, 수술 전 주의력 및 인지 조절 기능 평가를 위한 신경생리학적 검사법 개발에도 기여하고 있습니다.
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
Pretransplant AT1R-Abs is an independent risk factor for AR, especially acute cellular rejection, and is possibly associated with the risk of antibody-mediated injury. Pretransplant assessment of AT1R-Abs may be useful for stratifying immunologic risks.
We studied spectral components of human hippocampal EEG in relation to behavioral status in 19 patients with intractable complex partial seizures who had depth electrodes implanted into the anterior hippocampi as a part of their preoperative evaluations. Behavioral conditions included: eyes closed resting, eyes open resting, eyes open with a verbal task, and eyes open with a visuospatial task. Hippocampal EEG spectral power uniformly decreased during behavioral activation. EEG activation was qua
We investigated the integrity of attentional mechanisms following unilateral intracarotid amobarbital injection in 23 patients undergoing preoperative evaluation for epilepsy surgery. Performance for ipsilateral hand-button response to a quasi-random strobe flash was markedly altered following unilateral amobarbital injection as evidenced by decreased correct responses and increased perseverative errors. The increase in perseverations was inversely correlated with subsequent memory performance.
Recently, Luminex-crossmatch (LumXm) was introduced. The aim of this study was to evaluate clinical outcomes in sensitized recipients with a positive Luminex-crossmatch (LumXm (+)) and a negative complement-dependent cytotoxicity crossmatch (CDCXm (-)) after renal transplantation. Fifty-five renal transplant recipients with a CDCXm (-) and PRA class I or II ≥20% were enrolled in this study between February 2008 and December 2010 at Severance Hospital. Eighteen patients displayed LumXm (+) define
Low-dose SRL with ER-TAC was not inferior to MMF with ER-TAC with respect to efficacy and safety. When used for immunosuppression in kidney transplantation, low-dose SRL with ER-TAC can effectively prevent acute rejection and preserve renal function.
Mycophenolic acid (MPA) is one of many effective immunosuppressive drugs. However, MPA can induce cellular toxicity and impair cellular function in β-cells. To explore the effects of MPA and the relation between MPA and Trx-1, we used various methods, including an Illumina microarray, to identify the genes regulated during pancreatic β-cell death following MPA treatment. INS-1E cells (a pancreatic β-cell line) and isolated rat islets were treated with MPA for 12, 24, or 36 h, and subsequent micr
D-FRV/R-BW and donor age have significant impact on graft function. D-FRV/R-BW can be measured ahead of surgery. Therefore, measuring the D-FRV is useful to select a more optimal donor kidney among otherwise similar candidates during preoperative evaluation to improve posttransplant graft function.
