东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Atsutake Kosuge's research lab specializes in advanced electronic systems and signal processing, focusing on high-speed, low-power, and real-time data acquisition and processing technologies. Key research directions include mmWave radar systems for intelligent transportation and construction machinery, ultrafast optical pulse characterization for atomic-scale dynamics, FPGA-based hardware accelerators for robotics and deep learning, and high-bandwidth, non-contact interconnects for next-generation electronic devices. The lab emphasizes innovative integration of hardware-software co-design, energy efficiency, and miniaturization for practical applications in robotics, imaging, and communication systems.
Professor Yasushi Hirota's research lab focuses on the molecular and cellular mechanisms underlying female reproductive physiology, particularly embryo implantation, decidualization, and pregnancy maintenance. The lab investigates key signaling pathways—such as p53, mTORC1, HIF2α, and PAR2—involved in uterine receptivity, senescence, and inflammation, with translational aims to understand and treat infertility, preterm birth, and endometriosis. Using genetically engineered mouse models, the lab elucidates how hormonal regulation (especially progesterone) and stress-responsive pathways coordinate endometrial remodeling for successful pregnancy. Their work bridges basic reproductive biology with clinical reproductive disorders.
Professor Masahiro Shoji's research lab focuses on public health policy, disaster risk reduction, and biomedical innovation, with a strong emphasis on practical interventions that improve societal resilience and health outcomes. The lab investigates microfinance mechanisms as social safety nets, particularly in disaster-affected regions, and explores the effectiveness of school-based disaster education in fostering intergenerational knowledge transfer. It also conducts cutting-edge research in biomedical sciences, including the development of human monoclonal antibodies for early cancer detection and the establishment of evidence-based food allergen regulations in Japan. The lab integrates social science, public health, and life sciences to address pressing global challenges in health equity and safety.
Professor Eiji Abe's research lab specializes in the atomic-scale characterization of complex intermetallic and quasicrystalline materials, with a focus on long-period stacking ordered structures, quasicrystals, and their unique atomic arrangements. The lab employs advanced electron microscopy techniques, such as Z-contrast imaging and high-resolution electron diffraction, to uncover the structural and chemical ordering principles in these materials. A key research direction involves challenging conventional models of quasicrystal formation by demonstrating that large icosahedral clusters are not essential for quasicrystallinity, thereby redefining structural descriptions of such phases. The lab also extends its expertise into biomedical applications, particularly in spinal surgery and vertebral biomechanics, where structural and mechanical principles are applied to clinical outcomes in spinal tumor resection and spinal stenosis treatment.
Professor M. Otsubo's research lab specializes in granular materials and geomechanics, focusing on the micromechanical behavior of soils and particulate systems. The lab investigates the influence of particle-scale properties—such as surface roughness, size distribution, and contact mechanics—on the macroscopic stiffness, dynamic response, and failure mechanisms of granular materials. Using a combination of discrete element method (DEM) simulations and experimental testing, including dynamic plate wave tests and salt fog aging studies, the lab explores fundamental soil behavior under small strains and environmental degradation. Their work bridges the gap between particle-scale interactions and bulk material response, with applications in geotechnical engineering and material durability.
Professor Shinsuke Ohba's research lab focuses on the molecular mechanisms governing skeletal development, with a central emphasis on transcriptional regulation, signaling pathways, and cell lineage specification in bone and cartilage formation. The lab investigates key transcription factors such as Sox9, Runx2, and Gli proteins, as well as signaling pathways including Hedgehog and BMP, to understand how they orchestrate chondrocyte and osteoblast differentiation. Using integrative approaches combining mouse genetics, single-cell analysis, and epigenomic profiling, the lab uncovers cell-type-specific regulatory networks that control chromatin accessibility and gene expression during skeletogenesis. Their work provides fundamental insights into developmental biology and has implications for regenerative medicine and skeletal disorders.
Professor Ryusuke Matsunaga's research lab specializes in ultrafast quantum dynamics and nonlinear optics in quantum materials, with a focus on superconductors and carbon nanotubes. The lab investigates collective quantum modes such as the Higgs amplitude mode and trions using advanced terahertz spectroscopy and optical techniques, aiming to understand and control non-equilibrium quantum states. Key research directions include ultrafast manipulation of superconducting order parameters, many-body excitations in low-dimensional systems, and the role of electron correlation and spin-orbit coupling in quantum coherence.
Professor Takahiro Shimada's research lab specializes in computational materials science, focusing on the atomic-scale mechanisms governing fracture, defect formation, and electronic properties in functional oxides and nanomaterials. The lab employs first-principles calculations and molecular dynamics simulations to investigate phenomena such as crack propagation in nanoscale materials, intrinsic point defects in ferroelectrics like PbTiO₃, and the role of nonlinear localized modes in nanotube failure. A key focus is understanding how atomic-level defects and structural instabilities lead to macroscopic material behaviors, including ferroelectricity and ferromagnetism, with implications for next-generation electronic and energy materials. The lab also explores the fundamental limits of classical fracture mechanics and the design principles of multiferroic materials at the nanoscale.
Professor Takuya Aoki's research lab focuses on improving the quality and equity of primary care in Japan, with a strong emphasis on patient-centered outcomes. The lab investigates multimorbidity patterns and their impact on medication use, explores patient experience of primary care through validated tools like JPCAT and patient experience scales, and examines social determinants such as social isolation and health literacy that influence care quality. A central theme is enhancing primary care delivery to reduce health disparities and support person-centered, comprehensive care, particularly for older adults and vulnerable populations.
Professor Akira Yamamoto's research lab focuses on the intersection of bioinorganic chemistry and environmental catalysis, with two primary research directions: (1) investigating the role of metal ions such as iron(III) and aluminum(III) in the pathological aggregation of hyperphosphorylated tau protein in Alzheimer’s disease, emphasizing metal-induced protein misfolding and its redox-dependent mechanisms; and (2) developing advanced photocatalytic systems for sustainable energy and environmental applications, including syngas production via CO₂ reforming and selective photocatalytic reduction of NOx under visible light. The lab combines biochemical, spectroscopic, and catalytic approaches to understand and manipulate metal-protein and metal-photocatalyst interactions at the molecular level.
Professor T. Noguchi's research lab specializes in planetary science and cosmochemistry, focusing on the experimental and analytical study of extraterrestrial materials returned from asteroids and comets. The lab investigates space weathering processes, mineralogical and chemical alterations on airless bodies, and the effects of hypervelocity impacts on primitive meteorites and interplanetary dust. Using advanced analytical techniques such as Cs-corrected STEM and synchrotron X-ray diffraction, the lab examines nanoscale surface modifications and amorphization in samples from missions like Hayabusa and Hayabusa2, providing insights into the evolution of planetary surfaces in the inner solar system. The lab also conducts hypervelocity impact simulations using light-gas guns to understand the preservation and alteration of organic and mineral phases in extraterrestrial particles captured in silica aerogel.
Professor Wenzhe Sun's research lab specializes in transportation systems and mobility analytics, with a focus on public transit operations, large vehicle routing, and pandemic-related mobility behavior. The lab employs advanced data-driven methodologies—such as GPS trajectory analysis, RegARIMA modeling, and logistic regression on real-time transit data—to study bus bunching, passenger behavior, and the impacts of policy interventions on mobility patterns. Research also extends to demand estimation using passive transit data, emphasizing practical applications in urban planning and transportation management.
Professor Kaoru Sekiyama's research lab specializes in auditory-visual speech perception, with a focus on cross-linguistic differences in speech processing, particularly between Japanese and English. The lab investigates how visual speech cues influence auditory perception, especially in aging populations and in the context of audiovisual integration. A key theme is the impact of musical training on cognitive development in children and cognitive preservation in older adults, often exploring neuroplasticity through short-term instrumental interventions. The lab combines behavioral experiments with neuroimaging techniques to examine neural mechanisms underlying speech perception and cognitive function.
Professor Bernd Winter's research lab specializes in the electronic structure of liquids and aqueous interfaces, with a focus on water and its solutions. Using advanced photoelectron spectroscopy techniques—particularly liquid microjet methods combined with synchrotron radiation—the lab investigates valence and core-level electronic states of water, hydronium (H₃O⁺), hydroxide (OH⁻), and solvated ions. Their work reveals how solvent effects, such as electronic polarization and hydrogen bonding, influence ionization energies and electronic transitions in the liquid phase. The lab also explores the interplay between electronic and geometric structure in nanoscale clusters, especially copper clusters, to understand their stability and reactivity.
Professor Shinya Hanashima's research lab specializes in the chemical synthesis and structural elucidation of biologically active glycans, with a focus on sialylated and sulfated glycolipids. The lab develops innovative synthetic methodologies—particularly stereoselective sialylation and glycosylation techniques—enabling the efficient construction of complex oligosaccharides, including tumor-associated antigens and glycoconjugates with therapeutic potential. Key research directions include the design of glycosyltransferase inhibitors and the structure-activity relationship studies of natural and synthetic glycolipids, such as sulfoquinovosylglycerol derivatives, for anti-cancer and enzyme-inhibitory applications. The lab integrates solid-phase synthesis, polymer-supported strategies, and advanced protecting group chemistry to achieve high-yielding, selective glycan assembly.
Professor Kentaro Yaji's research lab specializes in advanced computational design methodologies, particularly in topology optimization and multi-fidelity simulation for engineering systems. The lab focuses on developing innovative optimization frameworks that integrate machine learning, high-fidelity physics simulations, and evolutionary algorithms to solve complex, nonlinear design problems in fluid and structural mechanics. Key research directions include multifidelity topology optimization, data-driven design using deep generative models, and the application of lattice Boltzmann methods for efficient fluid flow simulation and optimization.
Professor Kei Goto's research lab specializes in the design and synthesis of stable, reactive functional groups within sterically protected molecular cavities, particularly focusing on sulfur and selenium chemistry. The lab pioneers the stabilization of highly reactive intermediates—such as sulfenic and selenenic acids—by embedding them within bowl-shaped macrocyclic frameworks like calix[6]arenes, enabling their isolation, structural characterization, and study under ambient conditions. A central theme is the development of protective environments that prevent undesired side reactions (e.g., dimerization) while preserving reactivity toward small molecules, thereby mimicking enzymatic microenvironments. The lab’s work has provided direct spectroscopic evidence for key catalytic intermediates in enzymes like glutathione peroxidase, advancing mechanistic understanding of redox biology and catalysis.
Professor Toshihiro Isobe's research lab specializes in the design and synthesis of advanced functional materials, with a focus on rare-earth and transition metal oxides for environmental and biomedical applications. Key research directions include the development of antiviral inorganic materials—particularly cerium molybdates with tunable valence states—and materials exhibiting unique thermal expansion behavior, such as Zr₂Si₂O₁₂ with dual mechanisms of negative thermal expansion. The lab also investigates advanced ceramic processing techniques, including wet jet milling and slip casting, to fabricate high-performance porous filters and thin films with controlled microstructures for gas separation and functional coatings. These efforts integrate materials synthesis, structural characterization, and functional evaluation to address challenges in energy, health, and environmental sustainability.
Professor Wei Wang's research lab specializes in computational fluid dynamics and combustion science, with a focus on developing high-order numerical methods for stiff reactive flows and turbulent combustion. The lab investigates advanced numerical schemes, such as modified fractional step methods and high-resolution finite-difference techniques, to accurately capture discontinuities and reaction fronts in complex flow systems. Experimental validation is conducted through high-fidelity wind-tunnel studies, including particle image velocimetry (PIV) and hot-wire anemometry, to study natural ventilation and indoor airflow in building models. The integration of advanced numerical simulations with experimental data enables the lab to address challenges in energy-efficient building design and clean combustion technologies.
Professor Hitoshi Shirakawa's research lab specializes in molecular and cellular biology, with a focus on chromatin-associated proteins, nuclear dynamics, and the regulation of gene expression. The lab investigates high mobility group (HMG) proteins such as HMG14/17 and novel nuclear factors like NBP-45, exploring their roles in chromatin remodeling, transcriptional activation, and embryonic development. Additionally, the lab examines the neuroprotective and anti-inflammatory effects of isoprenoids—particularly menaquinone-4 (MK-4) and geranylgeraniol (GGOH)—in microglial cells and neuroinflammatory disorders, linking cellular metabolism to neurological function and disease. These studies integrate molecular cloning, gene regulation, and neuroimmunology to uncover novel therapeutic targets for neurodegenerative and inflammatory diseases.
