东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Kota Kadoi's research lab specializes in materials processing and welding metallurgy, with a strong focus on solidification cracking mechanisms in high-performance alloys, particularly stainless steels and nickel-based superalloys used in advanced manufacturing. The lab investigates the effects of processing parameters—such as welding speed, heat treatment, and solidification conditions—on microstructure evolution and defect formation. Key research directions include the development of quantitative evaluation methods for solidification cracking susceptibility, foam stabilization in aluminum melts, and the fundamental behavior of blowing agents like TiH₂ in aluminum foam fabrication.
Professor Norimasa Nakamura's research lab specializes in regenerative medicine and orthopedic tissue engineering, with a primary focus on enhancing the repair of musculoskeletal tissues such as ligaments, menisci, and cartilage. The lab investigates mesenchymal stem cells (MSCs), including those derived from induced pluripotent stem cells (iPSCs) and adult sources like adipose tissue and synovium, to develop cell-based therapies for osteoarthritis and ligament injuries. A key research direction involves optimizing culture conditions using human serum to improve MSC proliferation and differentiation while minimizing immunogenic risks. The lab also explores molecular mechanisms—such as decorin regulation in collagen fibrillogenesis—that influence tissue quality and mechanical function in scarred or degenerated joints.
Professor Shigeki Tokita's research lab specializes in ultrafast and mid-infrared photonics, focusing on the development of high-power, tunable, and mode-locked fiber lasers operating in the 3-micrometer wavelength range. The lab pioneers advanced fiber laser systems using rare-earth-doped ZBLAN fluoride glass fibers, emphasizing high-output power, efficient cooling techniques, and ultrafast pulse generation. Key research directions include laser-driven electron acceleration, terahertz surface wave excitation, and applications in ultrafast electron diffraction and high-field terahertz science. The lab also explores novel saturable absorbers, such as graphene, for compact, high-repetition-rate mid-infrared lasers.
Professor Piyush Ghasiya's research lab specializes in digital society and political communication, focusing on the intersection of media, extremism, and global crises. The lab investigates emergent socio-political issues through computational and linguistic analysis of digital discourse, particularly on social media and news platforms. Key research directions include the spread of hate speech during global health emergencies, the role of digital platforms in geopolitical conflicts, and the ideological framing of right-wing extremism in comparative contexts. The lab employs advanced natural language processing (NLP) and network analysis to uncover patterns in sentiment, discourse, and information dissemination.
Professor Sunil Kumar Maurya's research lab specializes in graph-based machine learning and high-performance computing, focusing on scalable and efficient algorithms for graph analytics and neural network architectures. The lab explores graph neural networks (GNNs) with an emphasis on feature aggregation, model interpretability, and handling heterophily in graph data, while also developing GPU-accelerated solutions for dynamic graph problems such as the Earliest Arrival Time. A key innovation lies in using GNNs to approximate complex graph centrality measures like betweenness centrality, enabling faster and more accurate identification of influential nodes in large-scale networks.
Professor Tsubasa Okaze's research lab specializes in environmental fluid mechanics and wind engineering, with a focus on snowdrift dynamics, pedestrian wind environments, and thermal comfort in urban and built environments. The lab develops advanced computational fluid dynamics (CFD) models, including large-eddy simulation (LES) and customized k-ε models, to simulate complex interactions between wind, snow particles, and urban structures. A key research direction involves integrating physiological signals such as EEG to enable objective, personalized assessment of thermal comfort for smart environmental control systems. The lab combines field measurements, wind tunnel experiments, and numerical simulations to improve predictive accuracy and practical applications in urban planning and climate-responsive design.
Professor Huie Zhu's research lab specializes in the design, synthesis, and application of functional polymeric and amphiphilic materials for advanced electronic and ferroelectric devices. The lab focuses on developing highly ordered, ultra-thin films and nanoparticles of poly(vinylidene fluoride) (PVDF) with dominant ferroelectric β-phase, enabling high-performance, solution-processable electronic components. Key research directions include the fabrication of Langmuir–Blodgett films, ferroelectric field-effect transistors, and magnetoresistive devices using PVDF as a dielectric or spacer layer, emphasizing precise control over film morphology, phase purity, and electrical properties at the nanoscale. The lab also pioneers novel interfacial assembly techniques for monodisperse nanoparticles and 2D monolayers with tailored surface and mechanical properties.
Professor Shinji Morimoto's research lab specializes in atmospheric chemistry and environmental science, focusing on the isotopic composition of greenhouse gases such as methane (CH₄) and carbon dioxide (CO₂) to understand their sources, sinks, and global budgets. The lab employs advanced atmospheric inversion techniques and long-term observational data from remote sites like Ny Ålesund, Svalbard, to investigate temporal and spatial variations in trace gases and their isotopes. Key research directions include the use of carbon and nitrogen isotope ratios (e.g., δ¹³C, δ¹⁵N) to constrain emission sources, particularly microbial and anthropogenic contributions, and to improve the accuracy of global carbon cycle modeling. The lab also conducts high-altitude balloon sampling to study stratospheric transport and atmospheric age of air, contributing to a deeper understanding of atmospheric dynamics and composition.
Professor Yuuki Shimizu's research lab focuses on the pathophysiological roles of the lymphatic system and cardiokines in cardiovascular and kidney diseases. The lab investigates lymphangiogenesis and vascular repair mechanisms, particularly in heart failure and lymphedema, with a strong emphasis on growth factors like VEGF-C, adiponectin, and Fstl1. A key research direction involves understanding how endogenous protective proteins—such as DJ-1 and Nrf2—modulate oxidative stress and proteasomal function in cardiac and renal tissues. The lab also explores therapeutic strategies using autologous ADRCs and small molecules (e.g., Na2S) to promote tissue repair and prevent organ dysfunction.
Professor Jeong-Hwan Park's research lab specializes in advanced semiconductor materials and devices, with a primary focus on III-nitride and III–V compound semiconductors for next-generation optoelectronic applications. The lab investigates fundamental challenges in micro-light-emitting diodes (µLEDs), including sidewall surface passivation, defect engineering, and nonradiative recombination suppression to enhance device efficiency and stability. Key research directions include remote epitaxy using graphene, substrate decomposition dynamics under MOCVD conditions, and the development of high-performance blue and red µLEDs for next-generation displays. The lab also explores computational protein folding models, demonstrating interdisciplinary expertise in materials science and computational biophysics.
Professor Shiro Imagama's research lab focuses on spinal cord injury, neurodegenerative diseases, and surgical outcomes in spinal surgery. The lab investigates the molecular mechanisms underlying amyotrophic lateral sclerosis (ALS), particularly the role of glycosaminoglycans like keratan sulfate in disease progression, as well as factors influencing postoperative complications and hospital length of stay after spinal interventions. The team integrates clinical neurosurgery with molecular biology to improve surgical planning, patient outcomes, and informed consent through evidence-based risk factor analysis and intraoperative neuromonitoring strategies.
Professor Naoko Okibe's research lab specializes in microbial biotechnology and biohydrometallurgy, focusing on the isolation, characterization, and application of extremophilic microorganisms—particularly acidophiles and thermophiles—for sustainable metal recovery and environmental remediation. The lab investigates the kinetics and mechanisms of bioleaching processes involving sulfide minerals like chalcopyrite and pyrite, with an emphasis on redox potential control and microbial community dynamics. Additionally, the lab explores biotechnological applications of industrially relevant bacteria such as *Corynebacterium glutamicum*, including genetic regulation and plasmid biology, contributing to synthetic biology and industrial biotechnology. Their work bridges fundamental microbiology with practical solutions for resource recovery and wastewater treatment.
Professor Tomoya Ishida's research lab specializes in musculoskeletal biomechanics and sports injury prevention, with a primary focus on lower limb joint mechanics during dynamic movements such as squatting and landing. The lab investigates the influence of center of pressure (COP) positioning, muscle moment contributions, and neuromuscular control—particularly in relation to anterior cruciate ligament (ACL) injury risk and return-to-sport outcomes. Key research directions include biomechanical analysis of movement patterns, especially sex differences in knee abduction during landing, and the development of predictive models for joint moment contributions using kinematic and kinetic data. The lab also explores clinical outcomes following ACL reconstruction, emphasizing psychological readiness and functional recovery.
Professor Masashi Tsuge's research lab specializes in experimental and theoretical astrochemistry, focusing on the formation and spectroscopic characterization of reactive species and molecular ions under astrophysically relevant conditions. The lab employs matrix isolation techniques—particularly using para-hydrogen matrices at cryogenic temperatures—to investigate protonated polycyclic aromatic hydrocarbons (H⁺PAHs), nitrogen-containing heterocycles, and exotic species such as noble-gas hydride complexes. A key focus is on understanding the role of quantum tunneling and matrix effects in reaction pathways relevant to interstellar chemistry, with strong integration of high-level quantum chemical calculations to support experimental findings. The lab also explores the reactivity of radicals on amorphous solid water surfaces, aiming to bridge gaps in the detection and identification of transient intermediates in cosmic ice chemistry.
Professor Mohamed Abdallah Mohamed Moustafa's research lab specializes in host-microbe interactions, with a focus on the microbiomes of wildlife and domestic animals, particularly in the context of environmental stressors and disease transmission. The lab investigates how anthropogenic factors such as captivity, translocation, and medical interventions alter host-associated microbiomes, especially in large mammals like Asian elephants and dromedary camels. A key research direction involves the molecular detection and characterization of tick-borne pathogens and symbionts using metagenomic and cell culture approaches, with particular attention to ixodid and argasid ticks. The lab also contributes to wildlife health monitoring through hematological and physiological studies in reptiles such as Nile monitors.
Professor Tetsuya Ogata's research lab specializes in cognitive robotics and human-robot interaction, focusing on the integration of language, motion, and emotion in autonomous robotic systems. The lab develops connectionist models and neural network architectures—such as RNNPB and precision-weighted prediction error mechanisms—that enable robots to learn and adaptively respond to linguistic commands and environmental contexts through behavioral experience. Key research directions include human motion recognition using motion history images and eigenspace techniques, emotional communication via hormone-inspired internal models, and computational modeling of psychiatric conditions like autism spectrum disorder to understand cognitive mechanisms.
Professor Hiroki Kabata's research lab focuses on the immunological crosstalk between the nervous and immune systems, particularly the role of innate lymphoid cells (ILC2s) and thymic stromal lymphopoietin (TSLP) in type 2 inflammation. The lab investigates the cellular and molecular mechanisms underlying allergic diseases such as asthma and atopic dermatitis, with a strong emphasis on how epithelial-derived signals regulate ILC2 activation and immune homeostasis. Using advanced genetic models and translational studies, the lab explores the therapeutic potential of targeting TSLP and its signaling pathways in inflammatory disorders.
Professor Takeshi Miyamoto's research lab focuses on the molecular mechanisms regulating osteoclast differentiation, function, and lineage commitment from common myeloid precursors. The lab investigates key signaling pathways, transcriptional regulators such as NFATc1, Bcl6, and Blimp1, and essential fusogenic proteins like OC-STAMP and DC-STAMP that control osteoclast multinucleation and bone resorption. By employing single-cell analysis and genetic models, the lab elucidates how imbalances in osteoclast formation contribute to skeletal diseases such as osteopetrosis, osteoporosis, and bone metastasis. Their work provides critical insights into therapeutic targets for bone disorders and cancer-related bone destruction.
Professor Kohji Hotta's research lab focuses on developmental biology and systems biology in ascidians, particularly *Ciona intestinalis* and *Ciona robusta*, using these chordate models to investigate the genetic and molecular mechanisms underlying notochord development, metamorphosis, and body plan formation. The lab specializes in creating standardized developmental and anatomical ontologies, generating high-resolution 4D imaging resources like the FABA atlas, and identifying Brachyury downstream genes through functional genomics and morpholino-based gene knockdown. Their work bridges gene regulation, cell dynamics, and calcium signaling in early chordate development, offering insights into vertebrate evolution and developmental systems biology.
Professor Tomohisa Sujino's research lab focuses on the immunological crosstalk between the gut, skin, and microbiota, with a central emphasis on regulatory T cells (Tregs) and intraepithelial lymphocytes (IELs) in mucosal immunity. The lab investigates how environmental cues, including microbial metabolites and aryl hydrocarbon receptor (AhR) ligands, shape the development, function, and plasticity of T cells in the intestinal and skin barriers. Key research directions include the metabolic regulation of T cell differentiation, the microbiota-driven biosynthesis of immunomodulatory molecules like kynurenic acid, and the role of tissue-resident T cells in inflammatory diseases such as IBD and psoriasis. The lab also explores translational applications of natural compounds like indigo naturalis for treating colitis.
