东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Qian Li's research lab specializes in advanced polymer membrane development with a focus on polyvinylidene fluoride (PVDF)-based materials for water treatment and separation technologies. The lab investigates membrane fabrication, surface modification, and functionalization using techniques such as atomic transfer radical polymerization (ATRP) and solvent engineering to enhance hydrophilicity, permeability, and antifouling properties. Key research directions include the design of zwitterionic coatings for improved membrane performance and the optimization of solvent systems to tailor membrane morphology and separation efficiency.
Professor Takuya Takeichi's research lab specializes in the genetic and molecular mechanisms underlying inherited skin disorders, with a focus on ichthyoses, epidermolysis bullosa (EB), and other keratinization defects. The lab employs advanced genomic technologies such as whole-exome sequencing and bioinformatics to identify disease-causing mutations in genes involved in skin barrier formation, particularly those related to ceramide biosynthesis and lipid metabolism. Key research directions include elucidating the pathogenic roles of novel genes like SDR9C7 and KDSR in ichthyosis, and investigating the genetic basis of rare dermatoses such as pityriasis rubra pilaris. The lab integrates clinical genetics with functional studies using patient-derived samples and mouse models to uncover disease mechanisms and improve diagnostics.
Professor Takashi Honda's research lab focuses on the molecular mechanisms underlying chromosome segregation and centromere function during cell division, with a particular emphasis on the roles of histone modifications and regulatory kinases such as Bub1 and Haspin. The lab investigates how phosphorylation of histone H2A-S121 and H3-T3 establishes the inner centromere microenvironment, enabling proper localization of the chromosomal passenger complex and shugoshin proteins essential for genomic stability. Their work bridges fundamental cell biology with implications in chromosomal instability and tumorigenesis, using fission yeast and human cell models. The lab also explores clinical correlates, including neurological complications following neurosurgical interventions and viral hepatitis treatment outcomes in elderly patients.
Professor Kenji Hamase's research lab specializes in the development of advanced analytical methodologies, particularly in chiral separation science and bioanalytical chemistry. The lab focuses on the sensitive and selective determination of D-amino acids in biological systems, with applications in neuroscience and clinical diagnostics. Key research directions include the design of innovative HPLC systems—such as 3D-HPLC with multiple column selectivities—for the accurate quantification of biologically relevant D-amino acids in complex matrices like plasma and brain tissues. The lab also investigates the physiological and pathological roles of D-amino acids, especially through the study of enzymes like D-amino acid oxidase in mouse models and human diseases such as chronic kidney disease.
Professor S. Kida's research lab specializes in computational fluid dynamics and vortex dynamics, with a focus on numerical simulations of turbulent flows and vortex reconnection mechanisms in viscous fluids. The lab investigates high-Reynolds-number flows using spectral and pseudospectral methods, exploring fundamental phenomena such as vortex fusion, fission, and helicity evolution in three-dimensional Navier–Stokes systems. Their work also extends to oceanographic modeling, particularly the dynamics of regional circulation and climate variability in tropical seas like the Indonesian Seas. The lab bridges theoretical fluid dynamics with geophysical applications, emphasizing the role of wind forcing and wave propagation in ocean transport and sea surface temperature variability.
Professor Betty Lala’s research lab focuses on indoor thermal comfort, particularly in naturally ventilated primary school classrooms in developing countries like India. Her work bridges gaps in understanding children’s physiological and cognitive vulnerability to extreme temperatures, with an emphasis on climate change impacts and adaptive behaviors. The lab pioneers data-driven, machine learning-based approaches to predict thermal comfort while addressing the unique challenges of children-specific models and multi-dimensional comfort metrics.
Professor Munekazu Ohno's research lab specializes in computational materials science, focusing on the development and application of quantitative phase-field modeling to understand and predict solidification microstructures in metallic and alloy systems. The lab emphasizes the theoretical foundations of phase-field models, including asymptotic analysis, antitrapping current formulations, and the incorporation of thermodynamic and kinetic constraints for accurate simulations. Key research directions include nonisothermal solidification, multicomponent alloy systems, and the integration of molecular dynamics with phase-field simulations using data assimilation techniques such as the ensemble Kalman filter. The lab also contributes to thermodynamic assessments of complex alloy systems, particularly Mg–Al–Mn, to support materials design and process optimization.
Professor Yongjin Qiu's research lab specializes in the molecular epidemiology and zoonotic potential of vector-borne pathogens, with a focus on spirochetes (Borrelia spp.), bartonellae, and Coxiella burnetii in wildlife, domestic animals, and their arthropod vectors across Africa and Asia. The lab employs molecular techniques such as PCR, real-time PCR, and 16S rRNA gene sequencing to detect, characterize, and understand the ecology and transmission dynamics of these emerging infectious agents in natural and agricultural ecosystems. A key research direction involves identifying reservoir hosts and vectors, particularly in understudied regions like Zambia and Southeast Asia, to assess public health risks and inform disease control strategies.
Professor Risa Kimura's research lab focuses on exploring innovative digital platforms that harness collective human sensory experiences—such as vision, hearing, and embodied perception—to foster deeper social connection, broaden perspectives, and support reflective, human-centered living in an increasingly complex world. The lab investigates how shared sensory data from wearable devices can be transformed into immersive, participatory experiences in virtual reality, promoting empathy, awareness, and creative problem-solving. Central to the lab’s work is the development of prototype platforms like CollectiveEars and Collective Human Eye Views, which aim to expand the scope of the sharing economy beyond physical assets to include human senses and viewpoints.
Professor Eisuke Shimizu's research lab focuses on advancing ophthalmic diagnostics and therapeutic strategies through innovative imaging technologies and artificial intelligence. The lab specializes in developing portable, video-recordable slit-lamp devices—such as the Smart Eye Camera (SEC)—to standardize anterior segment imaging for conditions like dry eye disease, cataracts, and ocular graft-versus-host disease. By integrating AI and machine learning with clinical ophthalmology, the lab aims to improve diagnostic accuracy and enable early detection of eye diseases. The research also explores immunomodulatory mechanisms in ocular pathologies, particularly the role of microglia in neurodegenerative diseases such as Alzheimer’s.
Professor Tatsuhiko Azegami's research lab focuses on developing innovative mucosal and plant-based vaccines to combat infectious diseases and chronic conditions such as hypertension and diabetic kidney disease. The lab specializes in novel immunization strategies, particularly intranasal and oral vaccines, leveraging the immune-modulating potential of antigens like RAGE, AT1R-PspA, and cholera toxin B subunit. A key research direction involves utilizing rice seeds as a stable, cost-effective platform for vaccine production, with demonstrated efficacy in animal models. The lab also investigates the dual benefits of vaccines in preventing both infectious diseases and associated systemic complications.
Professor Eiji Kikuchi's research lab specializes in urological oncology, with a primary focus on identifying and validating prognostic biomarkers in urothelial carcinoma and prostate cancer. The lab investigates the clinical significance of pathological factors such as lymphovascular invasion (LVI), tumor volume, and CD44v9 expression in predicting disease progression and survival outcomes. A key direction involves exploring the role of cancer stem cell markers and molecular pathways—particularly the CD44v9-xCT system—in modulating chemotherapy response and metastasis in muscle-invasive bladder cancer. The lab also evaluates the impact of surgical and reconstructive urological procedures on patient-reported outcomes and quality of life.
Professor Takahisa Murata's research lab specializes in vascular biology and endothelial cell signaling, with a focus on the molecular mechanisms regulating vascular permeability, endothelial nitric oxide synthase (eNOS) activity, and calcium signaling in endothelial cells. The lab investigates the roles of caveolin-1 and caveolae in vascular homeostasis, particularly in pathological conditions such as pulmonary hypertension, acute lung injury, and allergic inflammation. Using genetically engineered mouse models and intravital imaging techniques, the lab explores how post-translational regulation of eNOS and ion channel function contributes to vascular dysfunction and disease progression.
Professor K. Sato's research lab specializes in atmospheric science, with a primary focus on gravity wave dynamics, atmospheric circulation, and the role of small-scale atmospheric disturbances in global momentum and energy budgets. The lab investigates gravity wave sources, propagation, and their impacts on the mesosphere and stratosphere using high-resolution numerical models, long-term simulations, and observational data from radars and radiosondes. A key research direction involves understanding the interaction between gravity waves and large-scale atmospheric phenomena such as the quasi-biennial oscillation, polar night jets, and typhoons.
Professor Satoru Taguchi's research lab focuses on marine biogeochemistry and oncology, with key research directions including lipid metabolism in marine diatoms under nutrient-limited conditions and the development of oncolytic virus therapies for cancer treatment. The lab investigates how environmental factors such as silicate availability influence lipid production in diatoms, contributing to understanding marine carbon cycling. Concurrently, it explores the clinical potential of oncolytic viruses like T-VEC and Pexa-Vec in treating urological cancers, particularly metastatic urothelial carcinoma, with a focus on prognostic biomarkers and imaging-based diagnostics. The integration of molecular oncology with clinical imaging and biomarker discovery defines the lab’s translational research approach.
Professor Zeke Xie's research lab specializes in the theoretical foundations of deep learning optimization, with a focus on understanding how stochastic optimization algorithms like SGD and Adam select generalizable solutions. The lab investigates the dynamics of minima selection, particularly the role of gradient noise covariance and Hessian information in favoring flat minima, using novel theoretical frameworks such as Density Diffusion Theory (DDT). They also explore the limitations and improvements of regularization techniques like weight decay and adaptive optimizers in deep neural network training. Their work bridges theory and practice, aiming to explain and enhance the generalization behavior of deep learning models.
Professor Kengo Watanabe's research lab focuses on systems-level molecular mechanisms underlying cellular homeostasis, with a central emphasis on cell volume regulation, osmotic stress responses, and their roles in aging, metabolic disease, and cancer. The lab integrates multi-omics approaches—genomics, proteomics, and metabolomics—with advanced imaging and machine learning to uncover dynamic regulatory networks in human health and disease. Key research directions include the identification of osmosensors like ASK3 in volume recovery, the impact of gut microbiome and polygenic risk on metabolic phenotypes, and the role of ion/water transport in cancer cell migration and therapy resistance. The lab also investigates environmental toxicants and their DNA adducts, linking molecular perturbations to long-term disease outcomes.
Professor Teiji Sota's research lab specializes in evolutionary biology and ecological genetics, with a focus on speciation, phylogeography, and coevolutionary dynamics in insects and other arthropods. The lab investigates molecular mechanisms underlying reproductive isolation, such as genital morphology and mating incompatibility, using carabid beetles as model systems. It also explores adaptation to environmental stress, including desiccation resistance in mosquito eggs and host-specific interactions in pollination mutualisms. The lab integrates molecular phylogenetics, experimental ecology, and population modeling to understand evolutionary processes across diverse taxa.
Professor Tatsuya Akutsu's research lab specializes in computational systems biology and bioinformatics, focusing on modeling, inference, and control of biological networks—particularly genetic and regulatory networks. The lab develops mathematical and algorithmic approaches to infer network structures from time-series gene expression data using models such as Boolean networks, S-systems, and qualitative networks. A key research direction involves network controllability, especially through the minimum dominating set concept, to identify key regulatory nodes for system-wide control. The lab also works on advanced sequence representations for protein subcellular localization prediction, integrating local amino acid composition and spatial patterns.
Professor Teruo Ono's research lab specializes in nanoscale magnetism and spintronics, focusing on the electrical and magnetic properties of submicrometer and nanoscale magnetic structures. The lab investigates phenomena such as magnetic domain wall dynamics, spin-dependent electron transport, and giant magnetoresistance effects in nanowires, aiming to understand and control nanoscale spintronic devices. A key direction involves exploiting magnetic domain walls for novel electronic functionalities, including quantized conductance switching and colossal magnetoresistive sensing. The lab also explores the interplay between magnetic order and electronic transport at the nanoscale, with applications in next-generation memory and sensor technologies.
