东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Cheryl Lewis Ames's research lab focuses on the biology, ecology, and evolution of cnidarians, particularly jellyfish and box jellyfish, with a strong emphasis on venom biology, symbiosis, and biodiversity assessment. The lab integrates cutting-edge molecular techniques—such as transcriptomics, proteomics, and environmental DNA sequencing—with fieldwork and advanced imaging to explore unique biological structures like cassiosomes and to resolve taxonomic uncertainties in venomous species. A central theme is understanding the functional and evolutionary significance of specialized stinging cells and their role in predation, defense, and host-symbiont interactions.
Professor Vempi Satriya Adi Hendrawan's research lab specializes in climate risk assessment, with a focus on understanding the impacts of hydrological extremes—particularly droughts and floods—on global crop systems. The lab integrates remote sensing, hydrodynamic modeling, and climate projections to develop vulnerability curves and drought indices that quantify crop yield sensitivity to climate variability and extremes. Their work emphasizes data-driven approaches using multi-source datasets and machine learning to improve risk assessment and support climate-resilient agricultural planning.
Professor Koji Ohashi's research lab focuses on the multifaceted roles of adiponectin, an adipocyte-derived hormone, in metabolic and cardiovascular diseases. The lab investigates how adiponectin modulates immune cell polarization—particularly macrophage M1/M2 balance—protects against vascular insufficiency, and exerts renoprotective effects in kidney injury. Key research directions include the interplay between adiponectin, inflammation, oxidative stress, and endothelial function, especially through regulators like COX-2. The lab employs genetic mouse models and viral overexpression systems to dissect molecular mechanisms underlying adiponectin’s protective actions in obesity-related pathologies such as hypertension, diabetes, and atherosclerosis.
Professor Yoichiro Ogino's research lab specializes in oral and maxillofacial regenerative medicine, with a focus on bone regeneration, implant dentistry, and the biological mechanisms underlying osteoclastogenesis and osteoblast differentiation. The lab investigates the role of platelet-rich plasma and biomaterials such as low-crystalline carbonate apatite in enhancing bone formation and integration, particularly in sinus floor elevation and dental implant applications. Additionally, the lab explores the influence of surface topography on stem cell behavior through RhoA signaling pathways, aiming to optimize implant design for improved osseointegration. A growing emphasis is also placed on age-related oral functions, including swallowing and masticatory performance, in the elderly population.
Professor Takehiro Kawashiri's research lab specializes in neuroprotection and mechanisms of chemotherapy-induced peripheral neuropathy, with a focus on identifying molecular pathways and repurposing existing drugs to prevent or treat neuropathic pain. The lab investigates ion channels (e.g., L-type Ca²⁺, TRPM8), transcription factors (e.g., NFAT), and endogenous protective systems (e.g., Nrf2) in models of oxaliplatin, paclitaxel, and other chemotherapeutic agents. Key research directions include screening neuroprotective agents such as Ca²⁺ channel blockers, neurotropin, dimethyl fumarate, and donepezil, with translational emphasis on preserving anti-tumor efficacy while reducing neurotoxicity. The lab integrates in vitro cell culture models with in vivo rodent studies to bridge basic mechanisms and clinical applications.
Professor Hiro Kishimoto's research lab focuses on aging, physical activity, and health outcomes in older adults, with a strong emphasis on the interplay between physical function, mental health, and chronic conditions. The lab investigates the role of physical activity—particularly moderate-to-vigorous physical activity (MVPA)—in maintaining physical function and reducing the risk of poor health outcomes in community-dwelling older Japanese adults. It also explores biomarkers such as handgrip strength and sedentary behavior, using objective measures like accelerometers, to understand their associations with mortality and chronic pain. Additionally, the lab contributes to health informatics and data standards through work on grid computing and interoperable health data systems.
Professor Shinsuke Mizutani's research lab focuses on the interplay between oral health, aging, and systemic well-being, with a particular emphasis on gingival health, oral function, and cognitive decline in older adults. The lab investigates behavioral and psychological factors—such as self-efficacy and oral hygiene habits—that influence periodontal disease progression in young adults. It also explores the role of oral function, including masticatory performance, tongue pressure, and swallowing, in maintaining cognitive health and quality of life in aging populations. The lab’s work bridges clinical dentistry with public health, aiming to develop early preventive strategies for oral and cognitive decline.
Professor Tetsuya Yamamoto's research lab specializes in molecular and cellular biology, with a focus on lipid signaling, membrane biophysics, and the molecular mechanisms underlying cellular differentiation and tissue remodeling. The lab investigates the interplay between signaling molecules such as bone morphogenic proteins (BMPs), estrogens, interleukin-6 (IL-6), and transforming growth factor-beta (TGF-β) in cancer and hepatic cells, as well as the biophysical behavior of lipid membranes under external stimuli. A key direction involves understanding how hybrid lipids and membrane asymmetry influence domain formation, line tension, and vesicle stability in complex lipid systems, using theoretical and computational models. The lab also develops innovative synthetic methods for bioactive sphingolipids to support functional studies in cell signaling.
Professor Tomohiro Onodera's research lab specializes in regenerative medicine and tissue engineering, with a focus on cartilage and meniscal repair, developmental morphogenesis, and biomaterials for cell adhesion and regeneration. The lab investigates molecular mechanisms underlying epithelial branching during organ development—particularly the role of Btbd7 in cleft formation—and develops innovative biomaterials, such as glyco-functionalized polymer films and ultrapurified alginate gels, to enhance tissue repair. A key direction involves combining biocompatible scaffolds with minimally invasive surgical techniques to achieve cell-free, one-step cartilage regeneration, aiming for clinical translation with improved outcomes.
Professor Hisatomo Waga's research lab specializes in Arctic marine ecology and remote sensing, focusing on the impacts of climate change on phytoplankton dynamics, sea-ice properties, and marine ecosystem structure. The lab investigates spatiotemporal variations in phytoplankton blooms—particularly spring and fall blooms—using satellite-derived chlorophyll-a data and advanced radiative transfer modeling. Key research directions include understanding the role of mesoscale eddies in shaping phytoplankton size structure, monitoring sediment-laden sea ice through spectral albedo analysis, and improving predictions of species shifts using phytoplankton size structure dynamics. The lab integrates satellite observations with biophysical modeling to address critical questions in polar oceanography and ecosystem responses to environmental change.
Professor Kiminori Nakamura's research lab focuses on the intersection of host-microbe interactions, innate immunity, and gastrointestinal health, with a particular emphasis on Paneth cells and antimicrobial peptides such as α-defensins. The lab investigates how circadian rhythms, lifestyle factors like smoking and sleep duration, and metabolic factors influence Paneth cell function and intestinal microbiota homeostasis. Using human and murine models, the lab explores the molecular mechanisms underlying defensin secretion and its impact on disease susceptibility, including cardiovascular disease and inflammatory conditions. The research integrates immunology, microbiology, and translational medicine to understand how environmental and behavioral factors shape intestinal immunity and systemic health.
Professor Norihiro Togasaki's research lab specializes in advanced battery technologies, with a primary focus on lithium-ion and lithium–oxygen batteries. The lab investigates degradation mechanisms, electrochemical impedance spectroscopy (EIS) for non-destructive diagnostics, and innovative materials such as redox mediators and polypyrrole films to enhance battery performance and longevity. Key research directions include improving cycle stability, mitigating overcharge/over-discharge damage, and developing analytical methods for electrode utilization in all-solid-state batteries.
Professor Ramesh Sunam’s research lab focuses on the socio-political and economic dynamics of international labour migration, particularly in rural Nepal, with an emphasis on its transformative impacts on agrarian livelihoods, rural poverty, and social inequality. The lab explores how migration reshapes power relations, caste structures, and local governance, especially through remittances and the accumulation of social, cultural, and financial capital. It also investigates the interplay between migration, food security, forest governance, and institutional decentralization, highlighting the multidimensional precarity experienced by migrant workers and their communities.
Professor Kazuhiko Hirakawa's research lab specializes in low-dimensional electron systems, particularly in modulation-doped AlGaAs/GaAs heterostructures. The lab focuses on fundamental transport phenomena in two-dimensional electron gases, including electron mobility engineering, electron heating dynamics, and collective excitations such as 2D plasmons. Key research directions involve manipulating electron wave functions via novel field-effect transistor architectures, studying quantum transport in high magnetic fields, and exploring terahertz emission from hot electron systems. The lab combines advanced nanofabrication with precision transport and spectroscopic measurements to probe quantum phenomena in semiconductor heterostructures.
Professor Ryo Takita's research lab specializes in the development of innovative catalytic methodologies and selective transformation strategies in organic synthesis. Key research directions include transition-metal-free and earth-abundant metal-catalyzed reactions—particularly those involving indium(III) and zinc-based systems—for enantioselective alkynylation and carbonyl transformations. The lab also focuses on the controlled reduction of amides and hydromagnesiation of enynes, employing tailored hydride sources and in situ-generated reagents. Additionally, the group explores redox-active organic architectures, such as oligothiophene tweezers, for stimuli-responsive behavior and π-dimer formation.
Professor Yuichi Motoyama's research lab specializes in computational quantum many-body physics, focusing on strongly correlated electron systems and topological quantum phases in low-dimensional spin systems. The lab develops advanced numerical methods—such as loop cluster Monte Carlo and tensor network algorithms (e.g., TeNeS)—to study exotic quantum phenomena, including symmetry-protected topological order and Berry phases in SU(N) Heisenberg models. A key emphasis is on creating user-friendly, high-performance software tools like TeNeS and MateriApps to democratize access to cutting-edge simulations in computational materials science. The lab bridges theoretical physics with practical computational tools, enabling researchers to explore quantum matter with greater accessibility and precision.
Professor Takumi Ishihara's research lab specializes in advanced digital communication systems, with a primary focus on faster-than-Nyquist (FTN) signaling and its optimization in frequency-selective fading channels. The lab explores low-complexity detection, iterative channel estimation, and precoding techniques—particularly SVD and EVD-based precoding with optimal power allocation—to enhance spectral efficiency and achieve near-capacity performance. Key research directions include joint detection and estimation, colored noise mitigation, and the integration of advanced signal processing with modern coding schemes such as turbo codes and serial concatenation. The lab also investigates innovative transmission schemes like index modulation and frequency-domain equalization tailored for FTN systems.
Professor Kumiko Ui-Tei's research lab specializes in RNA interference (RNAi) mechanisms, with a focus on understanding the sequence determinants and structural features governing siRNA efficacy and off-target effects in mammalian systems. The lab investigates the thermodynamic and structural basis of siRNA-target interactions, particularly the role of the seed region in off-target silencing, and explores how nucleotide modifications—such as DNA substitutions—impact RNAi activity. Their work also examines the interplay between viral sensors like LGP2 and miRNA pathways, revealing novel regulatory networks in antiviral innate immunity. These studies contribute to the rational design of highly specific and efficient siRNAs for functional genomics and therapeutic applications.
Professor Satoru Inoue's research spans advanced materials science and theoretical particle physics. His lab focuses on the design and characterization of solution-processable organic semiconductors for flexible electronics, as well as the fundamental understanding of adsorption phenomena in mesoporous materials, including carbon nanotubes and silica. In parallel, the group investigates high-energy physics topics such as CP violation, electroweak baryogenesis, and electric dipole moment (EDM) constraints in models beyond the Standard Model, linking experimental particle physics with cosmological implications. The interdisciplinary work bridges nanomaterials synthesis, surface science, and theoretical particle physics.
Professor Tetsuo Sasano's research lab focuses on the genetic and molecular mechanisms underlying cardiac arrhythmias, particularly atrial fibrillation (AF) and idiopathic ventricular fibrillation (VF). The lab investigates the role of inflammation and genetic factors—such as IRX3 mutations—in the development of arrhythmogenic substrates, aiming to uncover novel therapeutic targets. A key research direction involves translating basic insights into improved risk stratification and preventive strategies for sudden cardiac death in structurally normal hearts. The lab also explores the pathophysiology of persistent and long-standing AF, with an emphasis on substrate remodeling and the potential for innovative ablation and pharmacological interventions.
