东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Hiroshi Komatsu's research lab focuses on the intersection of neuroscience, psychiatric disorders, and biomedical imaging, with a particular emphasis on understanding the neurobiological underpinnings of schizophrenia-spectrum disorders. The lab investigates retinal changes, genetic factors such as OLIG2 polymorphisms, and their links to brain structure and function, using multimodal imaging and molecular genetics approaches. A key direction involves exploring the role of autistic and depressive symptoms in self-stigma and recovery processes among patients with schizophrenia, aiming to inform personalized interventions.
Professor Hedong Zhang's research lab specializes in the molecular-level understanding of lubrication phenomena in advanced magnetic storage systems, with a focus on perfluoropolyether (PFPE) lubricants and organic friction modifiers. The lab employs advanced computational methods such as reactive molecular dynamics and Monte Carlo simulations to investigate lubricant spreading, decomposition mechanisms, and surface interactions under extreme conditions like those in heat-assisted magnetic recording (HAMR). Experimental validation is combined with simulations to explore surface patterning, molecular organization, and the effects of nano- and micro-textures on lubricant behavior.
Professor Kwang Su Kim's research lab specializes in mathematical modeling of viral dynamics, particularly focusing on SARS-CoV-2, MERS-CoV, and SARS-CoV, to understand within-host infection processes and optimize antiviral therapies. The lab also develops advanced biosensing platforms using graphene-based electrochemical impedance sensors and explores innovative signal processing techniques for brain-computer interfaces using functional near-infrared spectroscopy (fNIRS). Their interdisciplinary work bridges virology, computational biology, nanomaterials, and biomedical engineering to address critical challenges in infectious disease control and neurotechnology.
Professor Hiroshi Noguchi's research lab specializes in the development and characterization of metal-organic frameworks (MOFs), particularly copper-based MOFs, for gas adsorption and separation applications. The lab focuses on understanding the thermodynamic and kinetic behaviors of gases such as methane, nitrogen, and oxygen in porous materials under various conditions, including supercritical and low-temperature regimes. Key research directions include the investigation of gate-opening phenomena, adsorption isotherms, and the impact of intermolecular interactions on adsorption performance, with applications in gas storage and environmental technologies. The lab also addresses instrumental challenges in real-time gas analysis, such as correcting for mass spectrometer response delays in metabolic measurements.
Professor Yoshimasa Shiraishi's research lab specializes in clinical and surgical management of drug-resistant tuberculosis, with a particular focus on extensively drug-resistant tuberculosis (XDR-TB). The lab investigates the role of pulmonary resection as a therapeutic option for patients with advanced or refractory forms of the disease, especially in cases where medical therapy alone is insufficient. Their work contributes to the development of evidence-based surgical strategies in the context of global TB control challenges. The lab also emphasizes multidisciplinary approaches combining thoracic surgery, infectious disease management, and public health surveillance.
Professor Fujio Tsumori's research lab specializes in bio-inspired micro- and nano-scale devices, focusing on magnetically actuated artificial cilia and soft robotics. The lab develops advanced fabrication techniques—such as laser machining and imprinting—to create functional microstructures for energy applications and fluidic systems. Key research directions include enhancing solid oxide fuel cell performance through engineered interfacial mesostructures and designing efficient, miniaturized artificial cilia that mimic natural ciliary motion for use in micro-total analysis systems (µTAS). The lab also explores wave-like locomotion in soft robots inspired by biological organisms like worms and snails.
Professor Hiroaki Watanabe's research lab specializes in advanced materials synthesis and fluid dynamics, with a focus on functional materials for energy and biomedical applications. Key research directions include the development of hydrophilic surface-modified zirconia for improved biocompatibility in orthopedic implants, high-pressure synthesis of novel intermetallic compounds for hydrogen storage, and large-eddy simulation (LES) of turbulent flows in pulverized coal combustion systems to optimize low-NOx burner designs. The lab integrates experimental synthesis, advanced characterization techniques, and high-fidelity computational modeling to address challenges in materials performance and energy efficiency.
Professor Tapas Chakraborty's research lab specializes in aquatic biotechnology, focusing on the molecular mechanisms underlying fish reproduction, stress resilience, and genetic regulation. The lab investigates sex determination pathways, oocyte physiology, and the application of advanced biotechnologies such as CRISPR/Cas9 and RNAi for sustainable aquaculture. It also develops biosensors for environmental monitoring and explores probiotic interventions to mitigate thermal stress in fish. The research integrates molecular biology, functional genomics, and environmental biotechnology to enhance fish health and aquaculture productivity.
Professor Mitali Nag's research lab specializes in environmental remediation and waste management, with a primary focus on stabilizing hazardous heavy metals and mitigating greenhouse gas emissions from municipal solid waste and incineration residues. The lab investigates innovative, low-cost treatment technologies—such as using natural zeolites (e.g., mordenite), fishbone-derived hydroxyapatite, and pozzolanic bottom ash—to immobilize toxic metals like lead and zinc in fly ash. A key research direction involves understanding and controlling nitrous oxide emissions during landfill aeration and nitrification processes, particularly under varying temperature and oxygen conditions. The lab emphasizes sustainable, nature-based solutions for enhancing the environmental safety of waste-derived materials.
Professor Norifumi Iseda's research lab focuses on hepatocellular carcinoma (HCC) biology, with a central emphasis on the molecular mechanisms underlying tumor progression, treatment resistance, and immune microenvironment regulation. Key research directions include the role of Nrf2 signaling in ferroptosis and lenvatinib response, the interplay between ARID1A, PD-L1, and tumor-associated macrophages in HCC immunoevasion, and the clinical relevance of P-NRF2 expression in patient prognosis and cancer metabolism. The lab integrates clinical pathology with molecular oncology to identify novel biomarkers and therapeutic targets for HCC.
Professor Yoshihisa Sugimura's research lab focuses on neuroimmunology and neuroendocrinology, with a primary emphasis on the role of glial cells—particularly microglia—in central nervous system disorders such as osmotic demyelination syndrome (ODS) and hypothalamic inflammation. The lab investigates molecular mechanisms underlying neuroinflammation, including the regulation of signaling pathways like JAK2-STAT3 and the contribution of autoantigens such as rabphilin-3A in neurological autoimmunity. Additionally, the lab explores neuropeptide signaling, especially TIP39-PTH2 receptor interactions, in the control of neuroendocrine functions like vasopressin release. Recent work also extends to environmental health, examining carbon sequestration in port ecosystems as a climate change mitigation strategy.
Professor Hironobu Ozawa's research lab specializes in molecular and materials chemistry for sustainable energy conversion, with a primary focus on artificial photosynthesis and dye-sensitized solar cells. The lab develops molecular devices that mimic natural photosynthesis, particularly photo-hydrogen-evolving systems based on Ru(II) photosensitizers and Pt(II) co-catalysts, aiming to produce clean hydrogen fuel from water under visible light. Another key direction involves designing advanced dyes and co-adsorbents for high-efficiency dye-sensitized solar cells, achieving record power conversion efficiencies through optimized dye-surface interactions and electrolyte engineering. The lab emphasizes structure-activity relationships and mechanistic insights to guide the rational design of efficient, stable, and scalable solar energy conversion systems.
Professor Satoshi Nishimura's research lab specializes in geomechanics and multi-physical modeling of geomaterials, with a strong focus on the thermo-hydro-mechanical (THM) behavior of frozen soils and fine-grained clays. The lab investigates the mechanical response of soils under extreme conditions—such as freezing and thawing—using advanced experimental techniques like triaxial and hollow cylinder apparatus testing, combined with constitutive modeling based on effective stress and critical state concepts. Key research directions include the anisotropy of clay behavior, shear strength evolution under complex stress paths, and the role of microstructures and microtubules in mechanical properties of biological and geological materials. The lab also develops predictive models for volume change and residual states in soils subjected to repeated freeze–thaw cycles, with applications in civil infrastructure and artificial ground freezing.
Professor Yuji Nakamaru's research lab focuses on the molecular mechanisms underlying chronic inflammatory and autoimmune diseases, with a particular emphasis on the roles of oxidative stress, sirtuins (especially SIRT1), and trace elements like zinc in immune regulation and tissue remodeling. The lab investigates how dysregulation of these factors contributes to conditions such as chronic obstructive pulmonary disease (COPD), eosinophilic granulomatosis with polyangiitis (EGPA), and IgG4-related disease, particularly in the context of mucosal and systemic inflammation. Their work integrates molecular biology, immunology, and clinical observations to uncover novel therapeutic targets in chronic inflammatory disorders.
Professor Shinya Yoshino's research lab specializes in personality psychology and its intersections with health, environmental factors, and social attitudes in Japanese populations. The lab investigates the Big Five personality traits using large-scale survey data, examining their associations with physical health (e.g., BMI), mental well-being, tolerance toward foreign residents, and regional variations. A key focus is on how ecological and social factors—such as sunshine duration, population diversity, and lifestyle—modulate personality and health outcomes. The lab also contributes to methodological advancements in psychological assessment, including cross-linguistic validation of personality inventories like the BFI-2-J.
Professor Hiroyuki Yamagishi's research lab focuses on the genetic and molecular mechanisms underlying congenital heart and craniofacial disorders, with a particular emphasis on 22q11.2 deletion syndrome and its associated phenotypes. The lab investigates key transcription factors such as dHAND and Tbx1, exploring their roles in neural crest development, pharyngeal arch formation, and vascular smooth muscle cell differentiation. Using mouse models and human genetic analyses, the lab identifies critical regulatory elements and candidate genes involved in cardiac and craniofacial morphogenesis, contributing to the understanding of disease pathogenesis and potential therapeutic targets. The research also extends to clinical applications, including the use of imaging techniques like PET for assessing cardiac sarcoidosis and evaluating outcomes in chromosomal disorders such as trisomy 13 and 18.
Professor Eisuke Amiya's research lab focuses on the pathophysiological mechanisms linking vascular dysfunction, oxidative stress, and autonomic nervous system regulation in cardiovascular diseases. The lab investigates the roles of reactive oxygen species, NADPH oxidase, lipid rafts, and free cholesterol in endothelial dysfunction, particularly in conditions such as hypertension, diabetes, and hypercholesterolemia. A key research direction involves understanding how metabolic and structural alterations in cellular microdomains contribute to atherosclerosis and heart failure. The lab also explores clinical implications, including exercise intolerance in atrial fibrillation and the impact of uric acid metabolism on cardiovascular outcomes.
Professor Kojiro Sho's research lab specializes in urban sustainability and resilience, focusing on the interplay between urban planning, green infrastructure, and socio-spatial dynamics. Key research directions include the evaluation of nature-based solutions such as green and blue-green spaces for public health and climate adaptation, the impact of urban regeneration policies on housing markets and social equity, and the application of big data and machine learning to understand human behavior in urban environments. The lab also investigates innovative land-use planning tools, such as the Future Land-use Simulation (FLUS) model, to project and protect urban ecological networks over time.
Professor Daiki Nishiguchi's research lab specializes in active matter physics, focusing on the collective behavior of self-propelled particles such as bacteria and synthetic microswimmers. The lab investigates how geometric confinement and hydrodynamic interactions lead to emergent order, including long-range nematic and antiferromagnetic vortex lattices, as well as mesoscopic turbulence. By combining experiments, continuum modeling, and numerical simulations, the group uncovers fundamental principles governing non-equilibrium dynamics and symmetry breaking in active systems.
Professor Masataka Mogi's research lab specializes in the exploration of topological quantum materials, with a focus on magnetic topological insulators and van der Waals heterostructures. The lab investigates quantum anomalous Hall effects, proximity-induced magnetism, and ultrafast control of topological states through advanced epitaxial growth and spectroscopic techniques. Key research directions include engineering magnetic and topological interfaces, achieving electrical and optical control of topological phases, and developing novel spintronic and quantum devices based on 2D and heterostructured quantum materials.
