东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Kazuho Daicho's research lab specializes in the fundamental structural characterization and physical property engineering of cellulose-based nanomaterials, with a focus on cellulose nanofibers (CNFs) and their crystalline architecture. The lab investigates the relationship between molecular packing, crystallinity, and interfacial interactions in nanocellulose, particularly how interfacial ordering and grain boundary engineering influence mechanical and thermal properties. Key research directions include the development of precise analytical methods—such as solid-state NMR and helium pycnometry—to quantify true density, crystallinity, and molecular orientation in cellulose fibrils, enabling advanced design of sustainable nanocomposites and porous materials.
Professor Zhiqiang Liao's research lab specializes in nonlinear dynamics, spintronics, and stochastic computing, with a focus on leveraging physical phenomena such as magnetic relaxation, stochastic resonance, and noise-induced synchronization for advanced computing and sensing applications. The lab explores brain-inspired computing paradigms like reservoir computing and Ising machines, particularly through spintronic devices such as superparamagnetic tunnel junctions and spin glass materials, to achieve high-speed, low-power, and noise-robust information processing. A key research direction involves enhancing short-term memory and signal detection in nanoscale systems using non-Gaussian and colored noise, enabling robust logic operations and biomagnetic sensing.
Professor Nen Saito's research lab specializes in theoretical and computational biophysics, focusing on stochastic processes in complex biological systems. The lab develops advanced statistical mechanics and machine learning methods to study rare events in random matrix theory, reaction dynamics in small-molecule systems, and the physical mechanisms underlying cellular structures like macropinocytic cups. A central theme is the integration of mathematical modeling, Monte Carlo simulations, and deep learning to address challenges in shape analysis, protein motor dynamics, and evolutionary dynamics under phenotypic plasticity.
Professor Hikaru Yokoyama's research lab specializes in the neural control of human locomotion, focusing on how the brain and spinal cord coordinate muscle activity during walking and running. The lab investigates muscle synergies, cortical contributions to gait adaptation, and the effects of neurological conditions such as Parkinson’s disease and aging on motor control. Using non-invasive neuroimaging and neurophysiological techniques like EEG and EMG, the lab explores the modular organization of motor control and its modulation under various conditions, including split-belt treadmill walking and underwater walking. Their work bridges systems neuroscience with clinical applications, aiming to understand and improve gait function in health and disease.
Professor Nobuhisa Ishii's research lab specializes in ultrafast laser science and strong-field physics, focusing on the development of few-cycle, carrier-envelope phase-stabilized lasers in the mid-infrared to long-wavelength infrared range. The lab pioneers advanced optical parametric chirped-pulse amplification (OPCPA) techniques to generate high-energy, ultrashort pulses capable of driving high harmonic generation in the water window and soft X-ray region. Their work enables attosecond science in solids and molecules, with applications in real-time observation of electron and nuclear dynamics. The lab also explores nonlinear spectroscopy and wave packet dynamics using few-femtosecond pulses.
Professor Fumiaki Obata's research lab investigates the intricate interplay between metabolism, aging, and host-microbe interactions in *Drosophila melanogaster*. The lab focuses on how metabolic pathways—particularly one-carbon metabolism involving S-adenosylmethionine (SAM) and glycine N-methyltransferase (Gnmt)—regulate lifespan and stress responses. A central theme is the role of commensal gut microbiota, such as *Acetobacter persici* and *Gluconobacter* species, in modulating systemic immunity, metabolic homeostasis, and age-related decline. The lab also explores how developmental stressors and sterile inflammation driven by necrotic cell death influence long-term health and longevity through microbial and metabolic crosstalk.
Professor Yohei Yukutake's research lab specializes in active volcano seismology and geodynamics, focusing on the seismic and geodetic processes associated with fluid migration, faulting, and aseismic deformation in volcanic regions. The lab employs high-resolution seismic tomography, precise hypocenter determination using dense seismic networks, and joint analysis of seismic and geodetic data to unravel the mechanisms behind earthquake swarms, volcanic tremors, and induced seismicity. Their work emphasizes understanding the interplay between crustal fluids, pressurized hydrothermal systems, and fault slip in active tectonic environments such as Hakone Volcano in Japan. The lab also investigates the dynamic triggers of seismicity, including remote stress changes from large earthquakes, and the role of aseismic slip in swarm sequences.
Professor Tsuyoshi Takami's research lab specializes in the development and characterization of advanced functional oxides and fluoride-based materials for next-generation energy conversion and storage technologies. The lab focuses on ion-conducting materials, particularly those involving fluoride ions, with an emphasis on designing cathode materials for solid-state fluoride-ion batteries and optimizing thermoelectric materials through nanostructuring and defect engineering. Key research directions include crystal structure analysis using X-ray and neutron diffraction, understanding the electronic and magnetic properties of transition metal oxides, and exploring the interplay between structure, ion transport, and macroscopic properties in complex oxides with perovskite- and Ruddlesden-Popper-type structures.
Professor Masaki Kashiwara's research spans algebraic analysis, representation theory, and geometric representation theory. His work focuses on D-modules, holonomic systems, and the interplay between differential equations and algebraic geometry, particularly through the study of microlocal analysis and perverse sheaves. He has made foundational contributions to the theory of holonomic D-modules, quantized enveloping algebras, and the geometric realization of crystals via quiver varieties. His research also extends to the representation theory of affine Lie algebras and the structure of solution sheaves in complex analytic geometry.
Professor Kosuke Nogaki's research lab specializes in strongly correlated electron systems, with a focus on unconventional superconductivity, quantum criticality, and topological quantum phenomena. The lab explores the interplay between electron correlation, spin-orbit coupling, and broken symmetries—particularly in noncentrosymmetric and heterostructured materials—using advanced theoretical and computational methods. A central theme is the development and application of analytical continuation techniques, such as the Nevanlinna method, to extract real-frequency spectral functions from numerical data, enabling deeper insights into correlated and topological materials.
Professor Yusuke Okazaki's research lab specializes in freshwater microbial ecology, focusing on the diversity, distribution, and ecological roles of uncultivated bacterioplankton and viruses in deep, oxygenated lakes. The lab employs advanced molecular techniques such as 16S rRNA gene amplicon sequencing, metagenomics, and single-cell genomics to explore microbial community dynamics across vertical water column gradients and over time. A central theme is understanding the evolutionary and ecological drivers of microbial microdiversity, particularly in oligotrophic and stratified freshwater systems like Lake Biwa in Japan. The lab also investigates host-virus interactions and the functional potential of microbial communities through high-resolution reconstruction of metagenome-assembled genomes (MAGs).
Professor Hiroshi Kawamoto's research lab focuses on molecular mechanisms underlying hematopoietic lineage commitment, particularly in T cell development and the regulation of innate lymphoid cell subsets such as invariant natural killer T (iNKT) cells. The lab investigates signaling pathways, transcriptional regulation, and post-transcriptional control mechanisms—such as those mediated by small non-coding RNAs like SgrS—in cellular stress responses and immune cell fate decisions. A key area of interest is the role of cytokines and Notch signaling in maintaining multipotency or driving lineage specification in hematopoietic progenitors. The lab also explores the development and function of distinct iNKT cell subpopulations defined by surface markers like IL-17RB and CD4, contributing to understanding immune homeostasis and type 2 immunity.
Professor Shigeo Takaishi's research lab focuses on gastrointestinal cancer biology, with a central emphasis on cancer stem cells (CSCs) in gastric and pancreatic cancers. The lab investigates the molecular mechanisms underlying CSC maintenance, tumor initiation, and metastasis, particularly through transcription factors like SNAIL2 and signaling pathways involving gastrin and Helicobacter infection. Using in vivo models, patient-derived cells, and advanced molecular techniques such as cDNA microarrays and reporter mouse systems, the lab explores the origins and regulation of CSCs and their role in therapy resistance and poor prognosis. The research also extends to understanding the tumor microenvironment and inflammatory triggers in gastric carcinogenesis.
Professor Hidetatsu Outani's research lab specializes in musculoskeletal oncology and bone metabolism, focusing on the molecular mechanisms of rare bone tumors such as clear cell sarcoma and chondroblastoma, as well as the long-term outcomes and complications of bone tumor treatments. The lab investigates drug response mechanisms, epigenetic regulation of fusion oncogenes like *EWSR1::ATF1*, and the pathogenesis of atypical femoral fractures associated with long-term bone-modifying agents. Their work integrates preclinical models, including cell lines and xenografts, to advance personalized therapeutic strategies and improve patient outcomes in bone sarcomas and metabolic bone disorders.
Professor Shuaijie Zhao's research lab focuses on the reliability and materials science of power electronic packaging, particularly the interfacial interactions between epoxy encapsulants and metal substrates in high-power semiconductor devices. The lab investigates failure mechanisms such as copper diffusion, thermal oxidation degradation, and coefficient of thermal expansion (CTE) mismatch, with an emphasis on improving bonding reliability in next-generation compact, high-performance power modules. Their work combines advanced materials characterization, accelerated life testing, and multimodal data fusion for real-time driver safety monitoring.
Professor M. Yamada's research lab specializes in spintronics and advanced semiconductor devices, with a focus on spin injection, transport, and manipulation in group IV semiconductors—particularly germanium. The lab explores novel heterostructures, such as ferromagnet/semiconductor and delta-doped systems, to achieve efficient spin injection and long spin diffusion lengths at low temperatures. Key research directions include the development of high-performance spin-valve devices on silicon platforms, ultra-shallow Ohmic contacts for Ge-based devices, and innovative memory architectures like Hi-C RAM and multilevel CCD memory for high-density, low-power applications. The lab combines molecular beam epitaxy, advanced device fabrication, and spin transport measurements to push the limits of semiconductor spintronics and memory technology.
Professor Kunihiro Oka's research lab specializes in orthopedic surgery and biomedical engineering, focusing on the development of low-radiation 3D imaging techniques for accurate bone modeling and the clinical application of customized implants. The lab pioneers innovative surgical techniques, such as markerless 3D motion analysis and free vascularized fascio-fat graft interposition, to improve outcomes in complex congenital and traumatic bone disorders. A central theme is enhancing diagnostic accuracy and functional recovery with minimal radiation exposure and personalized implant solutions.
Professor Jianhao Wang's research lab focuses on advanced materials and systems for next-generation wireless communications and space electronics. The lab specializes in millimeter wave and massive MIMO channel estimation, integrated sensing and communication (ISAC) for 6G networks, and the reliability of electronic packaging under extreme conditions such as cryogenic temperatures and radiation exposure. Additionally, the lab explores biomedical applications of biodegradable materials, including collagen microneedles for targeted drug delivery in treating infections. These interdisciplinary efforts bridge telecommunications, materials science, and biomedical engineering to address challenges in future 6G systems, deep space exploration, and regenerative medicine.
Professor Sachiko Matsushita's research lab specializes in the design and fabrication of nanostructured functional materials, particularly mesoporous and periodically ordered titanium dioxide films for photocatalytic and optoelectronic applications. Her work focuses on controlling nano-scale architectures through templating methods using colloidal crystals, enabling precise manipulation of light-matter interactions and surface reactivity. The lab investigates phenomena such as light propagation in 2D colloidal arrays, photocatalytic activity, and the development of novel thermal energy conversion devices like sensitized thermal cells that operate without temperature gradients. These studies bridge materials science, surface chemistry, and energy conversion technologies.
Professor Shinsuke Miyajima's research lab specializes in advanced thin-film materials and heterojunction devices for next-generation photovoltaics. The lab focuses on developing high-quality wide-bandgap semiconductors—such as hydrogenated aluminum oxide, nanocrystalline silicon carbide, and perovskite/silicon tandem structures—for efficient, low-temperature processed solar cells. Key research directions include surface passivation, transparent conductive emitters, photon management in thin silicon, and tunnel recombination junctions for monolithic tandem devices. The lab combines materials synthesis, advanced characterization, and device simulation to achieve high efficiency and stability in silicon-based photovoltaics.
