探索全球顶尖大学的研究室——研究领域与主要论文一览无余。
Professor Luke P. Lee's research lab specializes in microfluidics, bioengineering, and lab-on-a-chip technologies, focusing on developing miniaturized, portable, and high-throughput systems for biomedical applications. His team pioneers innovative microfluidic devices for single-cell analysis, organ-on-a-chip models such as artificial liver sinusoids, and point-of-care diagnostics with integrated optical detection. The lab emphasizes the design of biologically inspired systems, including artificial compound eyes and controlled cell culture arrays, to enable long-term, dynamic monitoring of cellular behavior under physiologically relevant conditions. Their work bridges fundamental microfabrication techniques with translational applications in drug screening, toxicology, and personalized medicine.
Professor Jong Bhak's research lab specializes in comparative and evolutionary genomics, focusing on the genetic adaptations of mammals, particularly big cats and cetaceans, to extreme environments and specialized diets. The lab employs whole-genome sequencing and advanced bioinformatics to uncover molecular mechanisms underlying traits such as high-altitude adaptation, hypercarnivory, and stress resilience. It also engages in translational epigenomics, investigating DNA methylation dynamics in aging and metabolic interventions using next-generation sequencing technologies. The lab is actively involved in developing and validating cost-effective sequencing platforms for broad genomics applications.
Professor Yugo Yamashita's research lab specializes in interventional radiology and vascular medicine, with a primary focus on the management of acute vascular emergencies such as postpartum hemorrhage and venous thromboembolism. The lab investigates interventional therapies like arterial embolization for hemorrhagic control and evaluates anticoagulation strategies in patients with atrial fibrillation and thromboembolic disorders. Their work emphasizes real-world clinical outcomes, risk stratification using tools like the sPESI score, and optimizing treatment duration to balance efficacy and safety.
Professor Saulius Juodkazis's research lab specializes in ultrafast laser-based nanofabrication, focusing on the development of advanced 3D micro- and nano-fabrication techniques using femtosecond lasers. Key research directions include the creation of photonic crystals, stress-free nanorods, and free-form micro-optical components with sub-micrometer precision, enabling applications in photonics, optofluidics, and biomedical engineering. The lab pioneers innovative methods such as optical far-field-induced near-field breakdown (O-FIB) and laser-induced amorphization in sapphire, enabling high-resolution, atmospheric-processing-compatible nanomachining. Their work also emphasizes material resilience and post-processing stability, particularly in organic-inorganic hybrid materials like SZ2080 for high-power optical applications.
Professor Kazuhiko Igarashi's research lab focuses on the molecular mechanisms underlying cellular redox homeostasis, epigenetic regulation, and iron metabolism, with a central emphasis on the roles of transcription factors such as BACH1, NRF2, and METTL16 in disease pathways. The lab investigates how post-translational modifications, RNA methylation (m⁶A), and intracellular metabolite levels—particularly S-adenosylmethionine (SAM) and heme—regulate gene expression and cellular fate decisions, including ferroptosis and stress responses. Their work bridges epigenetics, metabolism, and cell death, revealing key regulatory nodes in cancer, neurodegeneration, and hematopoietic disorders.
Professor Fengwen Mu's research lab specializes in advanced semiconductor materials and heterointerface engineering for next-generation power electronics and nanoelectronics. The lab focuses on developing high-performance heteroepitaxial and wafer-scale integration techniques—particularly involving GaN, 4H-SiC, and β-Ga₂O₃—on high thermal conductivity substrates such as diamond and SiC to enhance thermal management and device reliability. Key research directions include surface-activated bonding (SAB) methods, interfacial engineering, and scalable integration strategies to enable high-power, high-frequency, and high-temperature electronic devices.
Professor Seung-Jae Lee's research lab focuses on the molecular and genetic mechanisms underlying aging and longevity, with a strong emphasis on model organisms such as *Caenorhabditis elegans*. The lab investigates key regulatory pathways including insulin/IGF-1 signaling, nutrient sensing, and chromatin remodeling, particularly the role of transcriptional coregulators like MDT-15 in lipid homeostasis and proteostasis. A central theme is understanding how environmental cues—such as temperature and dietary restriction—modulate aging through conserved cellular and metabolic networks. The lab also explores the epigenetic regulation of cancer-related genes, such as in rhabdoid tumors, linking chromatin dynamics to disease and aging.
Professor Sung Jin Kim's research lab specializes in thermal management and heat transfer enhancement in electronic cooling systems, with a focus on microchannel heat sinks, finned heat sinks, and advanced thermal modeling. The lab investigates innovative design optimization techniques—such as porous medium modeling and numerical simulation—to minimize thermal resistance and improve thermal performance. Their work bridges experimental validation with predictive modeling, contributing to the development of high-efficiency thermal solutions for electronics and power systems. The lab also develops empirical correlations for friction factor and Nusselt number to support practical heat sink design.
Professor Shukra Raj Paudel's research lab focuses on sustainable water resource management, with a strong emphasis on wastewater treatment, reuse, and the environmental impacts of aquaculture and urbanization in South Asia. The lab investigates innovative solutions such as biogas recovery from wastewater through anaerobic digestion and the reduction of greenhouse gas emissions, particularly nitrous oxide, from aquaculture systems. It also explores institutional and infrastructural challenges in achieving sustainable sanitation and hygiene (WASH) services, especially in rapidly urbanizing regions like Nepal’s Kathmandu Valley. The lab’s work bridges environmental engineering, climate resilience, and policy development to support the achievement of Sustainable Development Goals (SDGs).
Professor Jun-ichiro Inoue's research lab focuses on the molecular mechanisms underlying immune system regulation, particularly the roles of signaling molecules such as TRAF6 and NF-κB in immune cell development, tolerance, and antiviral responses. The lab investigates how these pathways govern thymic epithelial cell differentiation, T-cell maturation, and the pathogenesis of viral infections including SARS-CoV-2 and HTLV-1. Key research directions include signal transduction in lymphoid organ development, innate immune activation, and the identification of host factors targeted by pathogenic viruses. The lab also explores the therapeutic potential of repurposed drugs, such as nafamostat mesylate, to inhibit viral entry and fusion.
Professor Naoki Okada's research lab focuses on advancing cancer immunotherapy through innovative cellular and gene engineering approaches. The lab investigates chimeric antigen receptor (CAR) structure-function relationships to optimize CAR-T cell therapy for enhanced efficacy and safety. A key research direction involves developing adenoviral vectors, particularly RGD-modified variants, for targeted delivery of immunomodulatory molecules—such as chemokines and tumor antigens—into dendritic cells or tumor microenvironments. The lab also explores route-dependent immunization strategies and the role of antigen-presenting cells in shaping potent, durable antitumor immune responses.
Professor Yoshinao Oda's research lab specializes in molecular oncology and pathology, with a focus on the role of chromatin remodeling proteins, transcription factors, and drug resistance mechanisms in sarcomas and other malignancies. The lab investigates tumor suppressor proteins such as SMARCB1/INI1 and oncogenic regulators like YB-1, exploring their immunohistochemical expression, subcellular localization, and clinical correlations in sarcomas including malignant rhabdoid tumors, pleomorphic leiomyosarcomas, and synovial sarcomas. Key research directions include understanding the pathogenesis of aggressive soft tissue sarcomas, identifying prognostic biomarkers, and elucidating mechanisms of multidrug resistance involving ABC transporters and transcriptional regulators.
Professor Seung Hwan Ko's research lab specializes in the development of advanced nanomaterials and scalable fabrication techniques for next-generation flexible, stretchable, and transparent electronics. The lab focuses on designing and engineering long metallic nanowires, nanowelding processes, and nanostructured photoanodes to enhance electrical conductivity, mechanical robustness, and optoelectronic performance. Key research directions include solution-processed conductive networks, low-temperature sintering via laser and nanosoldering, and hierarchical nanostructures for high-efficiency energy conversion devices such as dye-sensitized solar cells. The lab's work bridges materials synthesis, nanofabrication, and device integration for applications in wearable electronics and sustainable energy technologies.
Professor Dong Won Chun's research lab specializes in advanced materials synthesis and nanofabrication, with a focus on silicon-based micro/nanostructures, magnetic and catalytic materials for energy applications, and functional materials for biomedical sensing. The lab develops innovative techniques such as magnetically guided metal-assisted chemical etching (MACE) to enable precise, high-speed fabrication of vertically aligned Si micro- and nanostructures, while also exploring hydrogen storage materials like Mg–Fe hydrides and magnetic alloys such as FePtSn for high-performance permanent magnets. Their work bridges fundamental materials science with practical applications in renewable energy, medical diagnostics, and nanoelectronics.
Professor Tea-Sung Jun's research lab specializes in the micro-mechanical behavior and deformation mechanisms of advanced light metal alloys, particularly titanium and magnesium alloys. The lab focuses on understanding strain rate sensitivity, local plasticity, and superplasticity at the microscale through in-situ mechanical testing, electron backscatter diffraction (EBSD), and nanoindentation. Key research directions include the role of microstructure—such as grain orientation, texture, and phase morphology—in determining mechanical properties under varying strain rates and temperatures, with applications in high-performance aerospace and structural materials.
Professor Sung-Min Yoon's research lab specializes in advanced oxide semiconductor materials and thin-film transistor (TFT) technologies, with a strong focus on transparent, flexible, and non-volatile memory devices. The lab explores novel ferroelectric and phase-change materials—such as Sb65Se35, Al:HfO2, and IGZO—engineered via atomic layer deposition for next-generation electronic applications. Key research directions include synaptic transistor devices for neuromorphic computing, high-performance and stable TFTs with low-temperature processes, and the development of transparent and flexible electronics for wearable and portable systems.
Professor Chul-Woo Kim's research lab specializes in structural health monitoring and vibration-based damage detection for civil infrastructure, with a strong focus on bridges. The lab investigates bridge-vehicle interaction dynamics, seismic response of railway bridges, and the application of advanced signal processing techniques—such as Bayesian FFT and time-series modeling—for identifying structural damage. Key research directions include developing robust damage identification methods using ambient and traffic-induced vibration data, with practical validation through laboratory and field experiments on real structures.
Professor Kengo Kinoshita's research lab specializes in computational biology and bioinformatics, focusing on the integration and analysis of multi-omics data to uncover biological insights. The lab develops advanced computational methods for gene coexpression analysis, protein function prediction using molecular surface geometry and electrostatics, and structural bioinformatics to identify conserved functional motifs in proteins. Key contributions include the development of databases such as COXPRESdb and eF-site, which support functional genomics and structural systems biology. The lab also plays a central role in the Tohoku Medical Megabank Project, contributing to the creation of comprehensive reference omics resources for the Japanese population.
Professor Ken Sakai's research lab specializes in the development of molecular-based, base-metal catalysts for sustainable energy conversion processes, with a strong focus on water oxidation and CO2 reduction in aqueous media. The lab pioneers the design of water-soluble porphyrin and polyoxometalate complexes—particularly cobalt, copper, and molybdenum-based systems—that enable efficient and selective photocatalytic reactions under visible or near-infrared light. Their work emphasizes the use of earth-abundant metals to achieve high turnover numbers and frequencies, aiming to replace precious metal catalysts in artificial photosynthesis. The lab also explores light-harvesting photosensitizers to extend the usable solar spectrum, particularly into the near-infrared region.
Professor Hae Jin Jeong's research lab specializes in marine microbial ecology, with a primary focus on the feeding ecology and nutritional physiology of dinoflagellates—particularly mixotrophic and heterotrophic species—in marine food webs. The lab investigates predator-prey interactions involving dinoflagellates, including their roles in energy transfer, carbon cycling, and the dynamics of harmful algal blooms. A key research direction is uncovering the mixotrophic nature of many dinoflagellates previously considered strictly autotrophic, revealing their ability to feed on bacteria, cyanobacteria, and other microplankton under varying nutrient conditions.
