探索全球顶尖大学的研究室——研究领域与主要论文一览无余。
Professor Yun Jung Heo's research lab specializes in the development of advanced biosensors and microfluidic systems for real-time, non-invasive, and point-of-care health monitoring. The lab focuses on innovative technologies such as biodegradable microneedle sensors for continuous glucose and cholesterol monitoring, implantable and wearable devices for physiological biomarker detection, and organ-on-a-chip platforms to study disease mechanisms like hepatic hypoxia. By integrating materials science, electrochemistry, and biomedical engineering, the lab aims to create smart, sensitive, and patient-friendly diagnostic tools for chronic disease management and early detection.
Professor Young Hae Choi's research lab specializes in metabolomics and green solvent technologies, focusing on the comprehensive analysis of metabolic networks in plants under stress conditions such as pathogen infection. The lab employs advanced NMR-based metabolomic approaches combined with multivariate data analysis to uncover key biochemical changes and identify bioactive compounds. A major research direction involves the development and application of natural deep eutectic solvents (NADES) as sustainable alternatives to conventional organic solvents in bioprocessing and natural product extraction.
Professor Myeong Gyu Kim's research lab specializes in health data science, focusing on the application of artificial intelligence and natural language processing to real-world health data. The lab investigates pharmacovigilance signals using social media, evaluates the metabolic effects of dietary patterns and supplements (such as ketogenic diets and n-3 fatty acids), and combats health misinformation—particularly during public health crises like the COVID-19 pandemic—using advanced NLP models like BERT. A central theme is leveraging digital health data to improve public health surveillance and decision-making.
Professor Xudong Zhou's research lab specializes in advancing Earth system modeling with a focus on improving the representation of land hydrology, river systems, and human-water interactions at high spatial resolution. The lab develops and refines global-scale hydrodynamic models—such as CaMA-Flood and ORCHIDEE—to better simulate surface water dynamics, flood hazards, and the impacts of human activities like irrigation and reservoir operations. Key research directions include enhancing river routing schemes, correcting hydrological model biases using rating curves and high-resolution topography, and quantifying uncertainties in flood risk assessments under changing climate and land-use conditions.
Professor Wataru Shihoya's research lab specializes in structural biology of G-protein-coupled receptors (GPCRs), with a focus on understanding the molecular mechanisms of receptor activation, ligand binding, and G-protein coupling. The lab employs advanced structural techniques such as X-ray crystallography and cryo-electron microscopy to elucidate high-resolution structures of medically relevant GPCRs, including endothelin receptors and β3-adrenergic receptors, in complex with agonists, antagonists, and signaling partners. Their work provides critical insights into receptor dynamics, conformational changes, and the structural basis for drug selectivity, contributing to the development of novel therapeutics for cardiovascular diseases, metabolic disorders, and cancer.
Professor Shin Kaneko's research lab specializes in regenerative medicine and cellular immunotherapy, focusing on the development of allogeneic stem cell-derived immune cells for cancer treatment. The lab pioneers the use of induced pluripotent stem cells (iPSCs) to generate T cells, natural killer cells, and invariant natural killer T (iNKT) cells with enhanced anti-tumor activity and reduced graft-versus-host disease risk. Key research directions include optimizing differentiation protocols, improving gene editing and transgene expression in hematopoietic stem cells, and engineering immune cells for 'off-the-shelf' therapeutic applications.
Professor Tomoaki Watanabe's research lab specializes in high-fidelity direct numerical simulations (DNS) of turbulent flows, with a primary focus on the dynamics of the turbulent/non-turbulent interface (TNTI). The lab investigates the transport mechanisms of vorticity, enstrophy, and passive scalars near the TNTI, particularly the roles of viscous diffusion, vortex stretching, and interface motion in mixing layers, jets, and stratified wakes. A key research direction involves identifying and characterizing the interface using vorticity magnitude, enstrophy, and potential enstrophy thresholds, revealing how turbulence is suppressed near the interface. The lab also explores Lagrangian particle dispersion and the dual regimes—ballistic in the viscous superlayer and Richardson-like in the turbulent sublayer—within the interface layer.
Professor Takatoshi Hikida's research lab focuses on the neural circuit mechanisms underlying psychiatric disorders and addiction, with a particular emphasis on the basal ganglia-thalamocortical circuits. The lab employs advanced genetic, imaging, and optogenetic techniques in rodent models to dissect the roles of specific neuronal populations—such as parvalbumin interneurons and cholinergic neurons in the nucleus accumbens—in behavior, learning, and disease pathology. By integrating neuroscience with computational modeling and AI-driven approaches, the lab aims to uncover the pathophysiological basis of schizophrenia, addiction, and related neuropsychiatric conditions.
Professor Mizuki Tada's research lab specializes in the design and characterization of advanced heterogeneous catalysts for selective and sustainable chemical transformations. The lab focuses on developing supported metal complexes on oxide surfaces—particularly silica—using innovative strategies such as molecular imprinting, surface functionalization, and site-isolated single-site catalysts. Key research directions include asymmetric catalysis, selective oxidation reactions, and in situ characterization of catalysts under operating conditions using advanced X-ray techniques like XAFS and laminography–XAFS. The lab also investigates dynamic surface processes in fuel cell catalysts, aiming to understand and mitigate degradation mechanisms in energy conversion devices.
Professor Hiroyuki Sugimori's research lab specializes in applying deep learning and artificial intelligence to medical imaging, with a focus on improving diagnostic accuracy, workflow efficiency, and image quality assurance. Key research directions include automated body weight estimation from CT scout images, anatomical structure detection in MRI and PET scans, and the development of robust deep learning models for classification and object detection across various imaging modalities. The lab also pioneers AI-based quality assurance systems for radiological imaging, particularly in chest X-rays, to support clinical decision-making and standardization.
Professor Murim Choi's research lab focuses on the genetic and molecular mechanisms underlying human diseases, with a strong emphasis on monogenic disorders affecting development and homeostasis. The lab integrates functional genomics, human genetics, and molecular physiology to identify disease-causing mutations and elucidate their pathophysiological mechanisms, particularly in the context of calcium signaling, ion channel function, and ectodermal development. Key research directions include the role of ion channels (e.g., KCNJ5) in endocrine diseases, the regulation of calcium transport in enamel formation, and the genetic basis of tooth and craniofacial malformations.
Professor Lak Shin Jeong's research lab specializes in medicinal chemistry and chemical biology, with a focus on the design and synthesis of novel nucleoside analogues for therapeutic applications. The lab investigates enzyme inhibitors targeting key regulatory pathways in cancer and neurodegenerative diseases, particularly through modulation of post-translational modifications such as cullin neddylation and kinase activity (e.g., DYRK1A). A major research direction involves the development of adenosine receptor ligands, especially 4'-modified nucleosides, to create potent and selective antagonists for treating cancer and inflammatory conditions. The lab also explores structure-activity relationships of antiviral agents, particularly L-oxathiolanyl nucleosides, for HIV-1 inhibition.
Professor Suk Kyun Hong's research lab specializes in advanced minimally invasive surgical techniques for living donor liver transplantation, with a primary focus on pure laparoscopic donor hepatectomy (PLDRH). The lab investigates the safety, feasibility, and long-term outcomes of laparoscopic approaches in both donors and recipients, emphasizing surgical innovation, intraoperative imaging (such as ICG fluorescence cholangiography), and 3D visualization. Their work contributes to the paradigm shift from anatomical to biologically guided criteria in selecting candidates for liver transplantation, particularly in hepatocellular carcinoma (HCC) patients. The lab is also at the forefront of advancing surgical training and standardization for complex laparoscopic liver surgery.
Professor Ki Won Lee's research lab focuses on the health-promoting effects of natural bioactive compounds, particularly phenolic phytochemicals and polyphenols found in common foods such as tea, wine, apples, and cocoa. The lab investigates their antioxidant, anti-inflammatory, and chemopreventive properties, with a special emphasis on mechanisms underlying cancer prevention, skin protection against UV damage, and modulation of oxidative stress-related diseases. Research also explores the molecular targets and signaling pathways affected by compounds like resveratrol, quercetin, and conjugated linoleic acid (CLA).
Professor Jae Young Kim's research lab specializes in environmental engineering and sustainable waste management, focusing on the fate and transport of organic pollutants in environmental matrices, particularly in geomembranes and landfills. The lab investigates mass transfer mechanisms of contaminants like veterinary antibiotics and hydrocarbons, evaluates ecological risks, and develops innovative solutions for waste valorization through anaerobic digestion. Key research directions include environmental risk assessment, bioremediation, and the optimization of measurement and modeling techniques for greenhouse gas emissions and contaminant behavior.
Professor Jinyoung Moon's research lab specializes in environmental health and epidemiology, focusing on the health impacts of environmental exposures such as PFAS, shift work, and industrial pollutants. The lab conducts rigorous meta-analyses and cohort studies to assess dose-response relationships between occupational and environmental exposures and chronic diseases, particularly cancer and lung disorders. It also develops advanced wastewater treatment technologies, such as membrane bioreactors with granular sulfur, to address emerging contaminants in industrial effluents. The lab emphasizes methodological rigor in epidemiological research, with strong attention to bias control, exposure quantification, and real-world applicability.
Professor Kook-Hyung Kim's research lab specializes in plant virology and fungal virology, with a focus on mycoviruses that influence fungal pathogenicity and host interactions. The lab investigates the molecular mechanisms of dsRNA viruses in filamentous fungi, particularly their role in reducing virulence and mycotoxin production, which has potential for biological control of plant pathogens. A key research direction involves overcoming vegetative incompatibility barriers to enable inter-strain or inter-species transmission of hypovirulence-associated mycoviruses through techniques like protoplast fusion. The lab also explores viral genome organization and host-virus interactions, including those involving plant-infecting viruses such as Tomato spotted wilt virus and Potato virus X.
Professor Hannah Oh's research lab focuses on the intersection of lifestyle factors, metabolic health, and cancer risk, with a particular emphasis on how dietary patterns, body composition, and hormonal biomarkers influence the development of obesity-related and hormone-sensitive cancers—especially breast cancer. The lab employs large-scale epidemiological studies, including nested case-control designs within prospective cohorts, to investigate the role of biomarkers such as estrogen receptor, progesterone receptor, Ki67, and IGF-1R in normal breast tissue as early indicators of cancer risk. Research also explores the impact of behavioral factors like smartphone use on adolescent body image and weight-related behaviors, highlighting the growing role of digital behaviors in health outcomes. The lab integrates molecular pathology with population-based epidemiology to identify modifiable risk factors and potential preventive strategies.
Professor Hyeong Sik Ahn's research lab focuses on endocrine and cardiovascular health, with a particular emphasis on the clinical and population-level impacts of thyroid disorders. The lab investigates the consequences of widespread thyroid cancer screening, especially its role in overdiagnosis and overtreatment, while also examining the long-term cardiovascular risks associated with thyroid dysfunction. Research spans epidemiological studies using large national databases to evaluate outcomes such as myocardial infarction and stroke in patients with hyperthyroidism or autoimmune thyroid disease.
Professor Soo-Youn Lee's research lab specializes in pharmacogenomics, personalized medicine, and molecular mechanisms underlying disease progression, with a focus on identifying genetic and metabolic biomarkers for precision therapy. The lab investigates genetic polymorphisms—particularly in drug-metabolizing enzymes like CYP2D6—and their clinical implications in diverse populations, including Koreans. It also explores molecular pathways involved in fibrosis, neurodegeneration, and cancer tropism, integrating genomics, proteomics, and metabolomics to uncover novel therapeutic targets. The lab's work bridges basic science and clinical application, aiming to improve diagnostic accuracy and treatment outcomes in conditions such as congenital adrenal hyperplasia, major depressive disorder, and brain tumors.
