Akira Harada

Cyclodextrins have been used as a cyclic component in the construction of supramolecular architectures. Recently they have been studied as a component in the construction of rotaxanes and catenanes. A cyclodextrin ring can translocate in some rotaxane and catenane structures. Therefore, much attention has been given to cyclodextrins as a component of molecular shuttles, motors, and machines. Attempts to design and synthesize molecular-level machines using cyclodextrins as a cyclic component are

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComplex formation between poly(ethylene glycol) and α-cyclodextrinAkira Harada and Mikiharu KamachiCite this: Macromolecules 1990, 23, 10, 2821–2823Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/ma00212a039https://doi.org/10.1021/ma00212a039research-articleACS PublicationsRequest reuse permissionsArticle Views5321Altmetric-Citations818LEARN ABOUT THESE METRI

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTPolymeric RotaxanesAkira Harada*, Akihito Hashidzume, Hiroyasu Yamaguchi, and Yoshinori TakashimaView Author Information Department of Macromolecular Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan* E-mail: [email protected]Cite this: Chem. Rev. 2009, 109, 11, 5974–6023Publication Date (Web):September 8, 2009Publication History Received17 February 2009Published online8 September 2009Published

CONSPECTUS: Cyclodextrins (CDs) have many attractive functions, including molecular recognition, hydrolysis, catalysis, and polymerization. One of the most important uses of CDs is for the molecular recognition of hydrophobic organic guest molecules in aqueous solutions. CDs are desirable host molecules because they are environmentally benign and offer diverse functions. This Account demonstrates some of the great advances in the development of supramolecular materials through host-guest interac

Recently, supramolecular chemistry has been expanding to supramolecular polymer chemistry. The combination of cyclic molecules and linear polymers has provided many kinds of intriguing supramolecular architectures, such as rotaxanes and catenanes. This tutorial review overviews construction of some supramolecular architectures formed by cyclodextrins or their derivatives with guest molecules. In the first part, the construction of supramolecular structures of cyclodextrins with some polymers (po

Supramolecular hydrogels formed by a host-guest interaction show self-healing properties. The cube-shaped hydrogels with β-cyclodextrin and adamantane guest molecules mend after being broken. The hydrogels sufficiently heal to form a single gel, and the initial strength is restored. Although contact between a freshly cut and uncut surface does not mend the gels, two freshly cut surfaces selectively mend.

Supramolecular materials cross-linked between polymer chains by noncovalent bonds have the potential to provide dynamic functions that are not produced by covalently cross-linked polymeric materials. We focused on the formation of supramolecular polymeric materials through host-guest interactions: a powerful method for the creation of nonconventional materials. We employed two different kinds of host-guest inclusion complexes of β-cyclodextrin (βCD) with adamantane (Ad) and ferrocene (Fc) to bin

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and properties of inclusion complexes of polyethylene glycol with .alpha.-cyclodextrinAkira Harada, Jun Li, and Mikiharu KamachiCite this: Macromolecules 1993, 26, 21, 5698–5703Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/ma00073a026https://doi.org/10.1021/ma00073a026research-articleACS PublicationsRequest reuse permissionsArticle Views

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and Characterization of Inclusion Complexes of Poly(propylene glycol) with CyclodextrinsAkira Harada, Miyuko Okada, Jun Li, and Mikiharu KamachiCite this: Macromolecules 1995, 28, 24, 8406–8411Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://doi.org/10.1021/ma00128a060RIGHTS & PERMISSIONSArticle Views2281Altmetric-Citations320LEARN ABOUT THESE METRICSArticle View

This review focuses on chemical sensors based on cyclodextrin (CD) derivatives. This has been a field of classical interest, and is now of current interest for numerous scientists. First, typical chemical sensors using chromophore appended CDs are mentioned. Various "turn-off" and "turn-on" fluorescent chemical sensors, in which fluorescence intensity was decreased or increased by complexation with guest molecules, respectively, were synthesized. Dye modified CDs and photoactive metal ion-ligand

The introduction of non-covalent bonds is effective for achieving self-healing properties because they can be controlled reversibly. One approach to introduce these bonds into supramolecular materials is use of host-guest interactions. This feature article summarizes the development of supramolecular materials constructed by non-covalent cross-linking through several approaches, such as host-guest interactions between host polymers and guest polymers, 1 : 2-type host-guest interactions, and host