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Chan‐Young Jung

Yonsei University · 医学

研究室紹介

Professor Chan-Young Jung's research lab focuses on renal and metabolic diseases, with a strong emphasis on kidney function decline in chronic conditions such as diabetes, cirrhosis, and viral infections like COVID-19. The lab investigates novel biomarkers—such as creatinine-cystatin C ratios and inflammatory/vasoconstrictive pathways—for improved risk prediction and early diagnosis. It also explores the impact of comorbidities like obesity and systemic inflammation on disease progression, particularly in critical illness settings. The lab integrates clinical epidemiology with translational research to refine diagnostic criteria and optimize patient outcomes.

diabetic kidney diseasebiomarkersacute kidney injurychronic hepatitis BCOVID-19

Research Overview

Papers
9
Total Citations
270
Papers (5y)
58
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
58total
2021
2022
2023
2024
2025
Citations per year (5y)
716total
20212022202320242025

Selected Papers

15
1
Review|209 citations·2022
Pathophysiologic Mechanisms and Potential Biomarkers in Diabetic Kidney Disease
Chan‐Young Jung, Tae‐Hyun Yoo
SJR Q1FWCI 26.4Diabetes & Metabolism JournalOA

Although diabetic kidney disease (DKD) remains the leading cause of end-stage kidney disease eventually requiring chronic kidney replacement therapy, the prevalence of DKD has failed to decline over the past 30 years. In order to reduce disease prevalence, extensive research has been ongoing to improve prediction of DKD onset and progression. Although the most commonly used markers of DKD are albuminuria and estimated glomerular filtration rate, their limitations have encouraged researchers to s

NephrologyMedicine
2
Article|68 citations·2022
Creatinine–cystatin C ratio and mortality in cancer patients: a retrospective cohort study
Chan‐Young Jung, Hyung Woo Kim, Seung Hyeok Han, Tae‐Hyun Yoo, Shin‐Wook Kang, Jung Tak Park
SJR Q1FWCI 7.2Journal of Cachexia Sarcopenia and MuscleOA

The creatinine-cystatin C ratio at the time of cancer diagnosis significantly associates with survival and hospitalization in cancer patients.

PhysiologyMedicine
3
Article|66 citations·2020
Clinical Characteristics of Asymptomatic Patients with COVID-19: A Nationwide Cohort Study in South Korea
Chan‐Young Jung, Haeyong Park, Dong Wook Kim, Yoon Jung Choi, Seong Woo Kim, Tae Ik Chang
SJR Q1FWCI 1.6International Journal of Infectious DiseasesOA

In this national cohort of over 10,000 patients with COVID-19, more than 60% of all cases in South Korea reported no symptoms at the time of diagnosis. Expanding criteria for contact tracing and testing to capture potential transmission before symptom onset should be urgently considered to inform control strategies for COVID-19.

Infectious DiseasesMedicine
4
Article|64 citations·2020
Creatinine–Cystatin C Ratio and Mortality in Patients Receiving Intensive Care and Continuous Kidney Replacement Therapy: A Retrospective Cohort Study
Chan‐Young Jung, Young Su Joo, Hyung Woo Kim, Seung Hyeok Han, Tae‐Hyun Yoo, Shin‐Wook Kang, Jung Tak Park
SJR Q1FWCI 4.9American Journal of Kidney DiseasesOA
NephrologyMedicine
5
Article|41 citations·2020
Association between Body Mass Index and Risk of Coronavirus Disease 2019 (COVID-19): A Nationwide Case-control Study in South Korea
Chan‐Young Jung, Haeyong Park, Dong Wook Kim, Hyunsun Lim, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Tae Ik Chang
SJR Q1FWCI 0.9Clinical Infectious DiseasesOA

Higher BMI levels were associated with a higher risk of contracting COVID-19.

Infectious DiseasesMedicine
6
Article|41 citations·2022
Metabolic dysfunction-associated fatty liver disease and risk of incident chronic kidney disease: A nationwide cohort study
Chan‐Young Jung, Hee Byung Koh, Keun Hyung Park, Young Su Joo, Hyung Woo Kim, Sang Hoon Ahn, Jung Tak Park, Seung Up Kim
SJR Q1FWCI 6.2Diabetes & MetabolismOA
EpidemiologyMedicine
7
Article|38 citations·2001
Preemptive oral ganciclovir therapy versus prophylaxis to prevent symptomatic cytomegalovirus infection after kidney transplantation
Chan‐Young Jung, Elisabeth Engelmann, K. Börner, G. Offermann
SJR Q3FWCI 0.4Transplantation Proceedings
EpidemiologyMedicine
8
Review|27 citations·2023
Hepatorenal syndrome: Current concepts and future perspectives
Chan‐Young Jung, Jai Won Chang
SJR Q1FWCI 5.5Clinical and Molecular HepatologyOA

Hepatorenal syndrome (HRS), a progressive but potentially reversible deterioration of kidney function, remains a major complication in patients with advanced cirrhosis, often leading to death before liver transplantation (LT). Recent updates in the pathophysiology, definition, and classification of HRS have led to a complete revision of the nomenclature and diagnostic criteria for HRS type 1, which was renamed HRS-acute kidney injury (AKI). HRS is characterized by severe impairment of kidney fun

HepatologyMedicine
9
Article|25 citations·2021
Advanced liver fibrosis measured by transient elastography predicts chronic kidney disease development in individuals with non-alcoholic fatty liver disease
Chan‐Young Jung, Geun Woo Ryu, Hyung Woo Kim, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
SJR Q1FWCI 2.4DiabetologiaOA
EpidemiologyMedicine
10
Article|24 citations·2022
Higher risk of kidney function decline with entecavir than tenofovir alafenamide in patients with chronic hepatitis B
Chan‐Young Jung, Hyung Woo Kim, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
SJR Q1FWCI 3.3Liver InternationalOA

ETV was associated with a higher risk of kidney function decline than TAF in patients with treatment-naïve CHB. Therefore, further prospective randomized studies are needed.

EpidemiologyMedicine
11
Article|23 citations·2021
Tenofovir is Associated With Higher Risk of Kidney Function Decline Than Entecavir in Patients With Chronic Hepatitis B
Chan‐Young Jung, Hyung Woo Kim, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
SJR Q1FWCI 2.7Clinical Gastroenterology and HepatologyOA
EpidemiologyMedicine
12
Article|21 citations·2021
Sex disparities and adverse cardiovascular and kidney outcomes in patients with chronic kidney disease: results from the KNOW-CKD
Chan‐Young Jung, Ga Young Heo, Jung Tak Park, Young Su Joo, Hyung Woo Kim, Hyunsun Lim, Tae Ik Chang, Ea Wha Kang, Tae‐Hyun Yoo, Shin‐Wook Kang, Joongyub Lee, Soo Wan Kim
SJR Q1FWCI 2.1Clinical Research in CardiologyOA
NephrologyMedicine
13
Article|15 citations·2022
Association of coronary artery calcium with adverse cardiovascular outcomes and death in patients with chronic kidney disease: results from the KNOW-CKD
Chan‐Young Jung, Hae‐Ryong Yun, Jung Tak Park, Young Su Joo, Hyung Woo Kim, Tae‐Hyun Yoo, Shin‐Wook Kang, Joongyub Lee, Dong‐Wan Chae, Wookyung Chung, Yong‐Soo Kim, Kook‐Hwan Oh
SJR Q1FWCI 1.7Nephrology Dialysis TransplantationOA

In Korean patients with CKD, the CACS was independently associated with adverse cardiovascular outcomes and all-cause death. The CACS also showed modest improvements in prediction performance over conventional cardiovascular risk factors.

Radiology, Nuclear Medicine and ImagingMedicine
14
Article|11 citations·2022
Novel biomarkers for diabetic kidney disease
Chan‐Young Jung, Tae‐Hyun Yoo
SJR Q1FWCI 1.3Kidney Research and Clinical PracticeOA

Although diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in patients with diabetes mellitus; its prevalence has failed to decline over the past 30 years. To identify those at high risk of developing DKD and disease progression at an early stage, extensive research has been ongoing in the search for prognostic and surrogate endpoint biomarkers for DKD. Although biomarkers are not used routinely in clinical practice or prospective clinical trials, many biomarker

NephrologyMedicine
15
Article|9 citations·2022
Similar risk of kidney function decline between tenofovir alafenamide and besifovir dipivoxil maleate in chronic hepatitis B
Chan‐Young Jung, Hyung Woo Kim, Jung Il Lee, Hyun Woong Lee, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim
SJR Q1FWCI 1.4Liver InternationalOA

TAF and BSV showed a similar risk of kidney function decline in patients with treatment-naïve CHB. Further prospective randomized studies are warranted for validation.

EpidemiologyMedicine

Research Areas

EpidemiologyNephrologyNutrition and DieteticsSurgeryPhysiologyHepatology

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