Yonsei University · 材料科学
Professor Heejun Park's research lab specializes in pharmaceutical formulation and drug delivery systems, with a strong focus on enhancing the bioavailability and stability of poorly water-soluble drugs. Key research directions include the development of advanced self-emulsifying and supersaturable SEDDS formulations, as well as engineered micro- and nanoparticle systems using techniques like W/O/W emulsification for controlled drug release. The lab also investigates the role of stabilizers and excipients in maintaining drug stability during processing and storage, particularly for sensitive peptides like exenatide. Additionally, the lab explores behavioral and technological aspects of information sharing in digital environments, integrating social psychology with technology adoption models.
Figures are computed from collected data and may differ slightly.
Many scholars and practitioners claim that a supportive organizational culture can enable the successful implementation of knowledge management (KM) technology initiatives. However, little empirical research has been conducted to define the key organizational culture attributes that support more effective application of KM technologies. In this study, the 44 cultural attributes of the organizational culture profile (OCP) and the knowledge management technology profile (KMTP) instruments were use
Self-emulsifying drug delivery systems (SEDDSs) are a vital strategy to enhance the bioavailability (BA) of formulations of poorly water-soluble compounds. However, these formulations have certain limitations, including in vivo drug precipitation, poor in vitro in vivo correlation due to a lack of predictive in vitro tests, issues in handling of liquid formulation, and physico-chemical instability of drug and/or vehicle components. To overcome these limitations, which restrict the potential usag
With the fast dissemination of smartphones, Mobile Payment Service was able to spread widely in a short time. Especially, MEPS, one of the most advanced type of MPS, holds a significant part in the South Korean market. However, most research up to now has focused on the initial use intention. Considering the maturity of the market, previous studies have limits on interpreting the current market situation. In order to reflect the current status and predict the future market, we considered the con
Micro-/nanoparticle formulations containing drugs with or without various biocompatible excipients are widely used in the pharmaceutical field to improve the physicochemical and clinical properties of the final drug product. Among the various micro-/nanoparticle production technologies, emulsion-based particle formation is the most widely used because of its unique advantages such as uniform generation of spherical small particles and higher encapsulation efficiency (EE). For this emulsion-based
The aim of this study was to investigate the effects of various stabilizers on the encapsulation efficiency and release of exenatide-loaded PLGA (poly(lactic-<i>co</i>-glycolic acid)) microspheres prepared by the water-in-oil-in-water (W/O/W) solvent evaporation (SE) method. It was shown that the stabilizers affected exenatide stability in aqueous solutions, at water/dichloromethane interfaces, on PLGA surfaces, or during freeze-thawing and freeze-drying procedures. Sucrose predominantly reduces
The purpose of this research is to explain the information-sharing process and investigate the intrinsic and extrinsic motivations that may induce information sharing on Facebook. Using the theory of planned behaviour, this research distinguishes between information-sharing intention and information-sharing behaviour. Based on self-determination theory, this research selects the extrinsic and intrinsic motivations that influence intention. Based on a survey of 233 South Korean Facebook users in
GCLs can be a novel and promising carrier system for targeted anticancer agent delivery. GCLs, which exhibited various characteristics depending on the coating degree, could be utilized in various ways in future studies.
Abstract The purpose of this study is to identify the relationship between organisational culture and service quality through the organisational learning framework in knowledge intensive business services (KIBS). This study set independent variables as four types of organisational cultures (group culture, developmental culture, rational culture, and hierarchical culture) from Quinn's competing values model. The dependent variable is KIBS quality based on SERVQUAL and the mediating variables that
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