Yonsei University · 医学
Professor Heung Dong Kim's research lab specializes in pediatric epilepsy and neurometabolic therapies, with a primary focus on the ketogenic diet (KD) as a treatment for drug-resistant epilepsy in children. The lab investigates dietary interventions such as the MCT-based KD and classic KD, evaluating their efficacy, safety, and suitability across different age groups. Additionally, the lab explores neurorehabilitation strategies, including tongue-to-palate resistance training, for improving oropharyngeal swallowing function in stroke patients with dysphagia. The research integrates clinical trials with mechanistic insights to optimize neurological outcomes in pediatric and adult populations.
Figures are computed from collected data and may differ slightly.
The MAD might be considered as the primary choice for the treatment of intractable epilepsy in children, but the classic KD is more suitable as the first line of diet therapy in patients <2 years of age.
Tongue function can affect both the oral and pharyngeal stages of the swallowing process, and proper tongue strength is vital for safe oropharyngeal swallowing. This trial investigated the effect of tongue-to-palate resistance training (TPRT) on tongue strength and oropharyngeal swallowing function in stroke with dysphagia patients. This trial was performed using a 4-week, two-group, pre-post-design. Participants were allocated to the experimental group (n = 18) or the control group (n = 17). Th
Resective surgery is a viable option in some patients to treat seizures that are associated with LGS, with a high probability of seizure control and better adaptive function.
The ketogenic diet (KD) is a high-fat, low-carbohydrate diet, in which fat, instead of glucose, acts as a major energy source through the production of ketone bodies. The KD was formally introduced in 1921 to mimic the biochemical changes associated with fasting and gained recognition as a potent treatment for pediatric epilepsy in the mid-1990s. Recent clinical and scientific knowledge supports the use of the KD in drug-resistant epilepsy patients for its anti-seizure efficacy, safety, and tole
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