北海道大学 · 医学
Sugimori教授の研究室では、深層学習を活用した医療画像診断支援技術の開発を主軸としています。特に、CTやMRI、PET画像における自動診断・アノテーション・品質保証のためのAIモデルの構築に注力しており、臨床現場での迅速かつ正確な意思決定支援を実現することを目的としています。また、患者の体重推定や画像のアーティファクト補正、解剖構造の自動検出など、画像処理と臨床応用を結びつける実用的で信頼性の高いAIソリューションの開発が進んでいます。
Figures are computed from collected data and may differ slightly.
This study aimed at elucidating the relationship between the number of computed tomography (CT) images, including data concerning the accuracy of models and contrast enhancement for classifying the images. We enrolled 1539 patients who underwent contrast or noncontrast CT imaging, followed by dividing the CT imaging dataset for creating classification models into 10 classes for brain, neck, chest, abdomen, and pelvis with contrast-enhanced and plain imaging. The number of images prepared in each
Body weight is an indispensable parameter for determination of contrast medium dose, appropriate drug dosing, or management of radiation dose. However, we cannot always determine the accurate patient body weight at the time of computed tomography (CT) scanning, especially in emergency care. Time-efficient methods to estimate body weight with high accuracy before diagnostic CT scans currently do not exist. In this study, on the basis of 1831 chest and 519 abdominal CT scout images with the corres
Background and purpose. This study evaluated a modified specialized convolutional neural network (CNN) to improve the accuracy of medical images. Materials and Methods. We defined computed tomography (CT) images as belonging to one of the following 10 classes: head, neck, chest, abdomen, and pelvis with and without contrast media, with 10,000 images per class. We modified the CNN based on the AlexNet with an input size of 512 × 512. We resized the filter sizes of the convolution layer and max po
Recently, deep learning technology has been applied to medical images. This study aimed to create a detector able to automatically detect an anatomical structure presented in a brain magnetic resonance imaging (MRI) scan to draw a standard line. A total of 1200 brain sagittal MRI scans were used for training and validation. Two sizes of regions of interest (ROIs) were drawn on each anatomical structure measuring 64 × 64 pixels and 32 × 32 pixels, respectively. Data augmentation was applied to th
Deep learning technology is now used for medical imaging. YOLOv2 is an object detection model using deep learning. Here, we applied YOLOv2 to FDG-PET images to detect the physiological uptake on the images. We also investigated the detection precision of abnormal uptake by a combined technique with YOLOv2. Using 3,500 maximum intensity projection (MIP) images of 500 cases of whole-body FDG-PET examinations, we manually drew rectangular regions of interest with the size of each physiological upta
A large number of images that are usually registered images in a training dataset are required for creating classification models because training of images using a convolutional neural network is done using supervised learning. It takes a significant amount of time and effort to create a registered dataset because recently computed tomography (CT) and magnetic resonance imaging devices produce hundreds of images per examination. This study aims to evaluate the overall accuracy of the additional
Background: Chest X-ray (CXR) imaging is the most common examination; however, no automatic quality assurance (QA) system using deep learning (DL) has been established for CXR. This study aimed to construct a DL-based QA system and assess its usefulness. Method: Datasets were created using over 23,000 images from Chest-14 and clinical images. The QA system consisted of three classification models and one regression model. The classification method was used for the correction of image orientation
Purpose: A deep learning technique was used to analyze the triceps surae muscle. The devised interpolation method was used to determine muscle’s volume and verify the usefulness of the method. Materials and Methods: Thirty-eight T1-weighted cross-sectional magnetic resonance images of the triceps of the lower leg were divided into three classes, i.e., gastrocnemius lateralis (GL), gastrocnemius medialis (GM), and soleus (SOL), and the regions of interest (ROIs) were manually defined. The supervi
Estimation of human age is important in the fields of forensic medicine and the detection of neurodegenerative diseases of the brain. Particularly, the age estimation methods using brain magnetic resonance (MR) images are greatly significant because these methods not only are noninvasive but also do not lead to radiation exposure. Although several age estimation methods using brain MR images have already been investigated using deep learning, there are no reports involving younger subjects such
Cardiac function indices must be calculated using tracing from short-axis images in cine-MRI. A 3D-CNN (convolutional neural network) that adds time series information to images can estimate cardiac function indices without tracing using images with known values and cardiac cycles as the input. Since the short-axis image depicts the left and right ventricles, it is unclear which motion feature is captured. This study aims to estimate the indices by learning the short-axis images and the known le
Our proposed method is capable of producing images that are comparable to the original full-acquisition-time images, allowing for a reduction of acquisition time/injected dose in pediatric <sup>99m</sup> Tc-DMSA planar imaging.
Convolutional neural networks (CNNs) in deep learning have input pixel limitations, which leads to lost information regarding microcalcification when mammography images are compressed. Segmenting images into patches retains the original resolution when inputting them into the CNN and allows for identifying the location of calcification. This study aimed to develop a mammographic calcification detection method using deep learning by classifying the presence of calcification in the breast. Using p
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