Yonsei University · 医学
Professor Hyun Joo Kim's research lab specializes in critical care anesthesiology and respiratory physiology, with a focus on advanced airway management techniques, protective strategies for healthcare workers during infectious disease outbreaks, and the cellular mechanisms underlying lung injury and repair. The lab investigates innovative respiratory support technologies such as high-flow nasal oxygenation and video laryngoscopes to improve patient outcomes in difficult airway scenarios. Additionally, the lab explores molecular pathways involved in acute lung injury, particularly the role of lipid mediators and integrin signaling in alveolar epithelial repair.
Figures are computed from collected data and may differ slightly.
The following guidelines are based on recommendations from the Anesthesia Patient Safety Foundation (APSF) for working with patients who have and the other literature [2-5], and can be modified and adapted to the circumstances of each institution or hospital.When managing patients with confirmed or suspected COVID-19 infection, it is of utmost importance to protect health care workers from infection.All medical personnel must be provided with personal protective equipment (PPE) to prevent drople
High-flow nasal oxygenation (HFNO) is a promising new technique for anesthesiologists. The use of HFNO during the induction of anesthesia and during upper airway surgeries has been initiated, and its applications have been rapidly growing ever since. The advantages of this technique include its easy set-up, high tolerability, and its abilities to produce positive airway pressure and a high fraction of inspired oxygen and to influence the clearance of carbon dioxide to some extent. HFNO, via a na
Acute lung injury leads to type I alveolar epithelial cell (AEC) death, denudation of the alveolar basement membrane, and formation of an alveolar provisional matrix from fibronectin, fibrinogen, and type I collagen. The provisional matrix provides a scaffold for alveolar repair. To restore normal lung architecture, surviving type II AECs must reepithelialize denuded alveoli. We examined whether AECs migrate on provisional matrix proteins and whether integrins mediate this migration using a Boyd
Compared to conventional haemodynamic therapy, goal-directed haemodynamic therapy does not reduce hospitalization periods; it may, however, reduce the length of intensive care unit stays and increase flap survival rates. Further studies including multi-centre trials with larger sample sizes are warranted.
Our present results corroborate the hypothesis that the BLT2 receptor is involved in 12(S)-lipoxygenase-product-induced scratching in ICR mice. We also confirmed that this animal model could be a valuable means of evaluating the effects of BLT2 receptor antagonists.
We hypothesized that the McGRATH MAC would decrease the time of intubation compared to C-MAC for novices. Thirty-nine medical students who had used the Macintosh blade to intubate a manikin fewer than 3 times were recruited. The participants performed sequential intubations on the manikin in two simulated settings that included a normal airway and a difficult airway (tongue edema). The intubation time, success rate of intubation, Cormack-Lehane grade at laryngoscopy, and difficulty using the dev
To establish stable and long-term gene expression in vitro and in vivo, we developed a lentiviral vector system carrying sodium iodide symporter (hNIS) gene under UbC promoter, and transfected this into a colon cancer cell line. The in vitro and in vivo kinetics of radioiodine and [99mTc]-pertechnetate were then investigated, and the therapeutic effect of 1-131 was evaluated in this system. The hNIS gene was transferred into CT26 cells using lentivirus containing UbC promoter. In vitro iodide up
Open papers in the app to read, cite, and organize with AI.
