Seoul National University · 医学
Professor Hyung-Jun Kim's research lab focuses on clinical and translational research in infectious diseases, particularly nontuberculous mycobacterial (NTM) pulmonary disease, with an emphasis on developing predictive scoring systems for mortality and optimizing treatment strategies. The lab also investigates clinical decision support systems in emergency medicine, such as sepsis alerts, and explores patient outcomes in critical conditions like COVID-19. Additionally, the lab contributes to clinical research in interventional radiology and surgical decision-making, particularly regarding lung nodules and their risk of progression. The work integrates clinical epidemiology, patient-centered outcomes, and evidence-based medicine to improve diagnostic and therapeutic approaches in pulmonary and critical care medicine.
Figures are computed from collected data and may differ slightly.
In the development of autonomous vehicles, the main focus of sensor research has been in relation to environmental perception, and only minimal work has focused on the human-vehicle interaction perspective. However, human factors need to be considered to ensure the safe operation of partially autonomous vehicles. This study briefly introduces a design methodology for the takeover request (TOR) time in National Highway Traffic Safety Administration Level 3 vehicles and compares four different TOR
Maintenance (≥6 months) of ethambutol and rifampicin with macrolide was associated with the most favorable treatment outcomes among patients with MAC-PD. Given the association between ongoing ethambutol use and microbiological cure, clinicians should maintain ethambutol unless definite adverse events develop.
Concurrent pleural attachment and indentation are risk factors for VPI, and the odds increase with larger solid portion in subsolid nodules. Considering the risk of recurrence, early surgical resection could be encouraged in these patients.
These findings suggest that sepsis alert systems in EDs were associated with better patient outcomes along with better adherence to sepsis management protocols. These systems hold promise for enhancing ED responses to sepsis, potentially leading to better patient outcomes.
The mortality rates of COVID-19 vary across the globe. While some risk factors for poor prognosis of the disease are known, regional differences are suspected. We reviewed the risk factors for critical outcomes of COVID-19 according to the location of the infected patients, from various literature databases from January 1 through June 8, 2020. Candidate variables to predict the outcome included patient demographics, underlying medical conditions, symptoms, and laboratory findings. The risk facto
This study examines the religious life of reformist Muslims in a Yogyakarta village. The foci of this discussion are on Muslim villagers' construction, with the help of the reformist paradigm, of the image of the 'good Muslim' and 'Muslim-ness', on their efforts to incorporate an (reformist) Islamic framework to question takenfor-granted practices and ideas, on the position of traditional practices and ideas and their relation to reformist Islam, and on the interplay of villagers who show a stro
This study examines the religious life of reformist Muslims in a Yogyakarta village. The foci of this discussion are on Muslim villagers’ construction, with the help of the reformist paradigm, of the image of the ‘good Muslim’ and ‘Muslim-ness’, on their efforts to incorporate an (reformist) Islamic framework to question taken-for-granted practices and ideas, on the position
The abnormal accumulation of alpha-synuclein (α-syn) aggregates in neurons and glial cells is widely known to be associated with many neurodegenerative diseases, including Parkinson's disease (PD), Dementia with Lewy bodies (DLB), and Multiple system atrophy (MSA). Mitochondrial dysfunction in neurons and glia is known as a key feature of α-syn toxicity. Studies aimed at understanding α-syn-induced toxicity and its role in neurodegenerative diseases have primarily focused on neurons. However, a
The endoplasmic reticulum (ER) is a major organelle involved in protein quality control and cellular homeostasis. ER stress results from structural and functional dysfunction of the organelle, along with the accumulation of misfolded proteins and changes in calcium homeostasis, it leads to ER stress response pathway such as unfolded protein response (UPR). Neurons are particularly sensitive to the accumulation of misfolded proteins. Thus, the ER stress is involved in neurodegenerative diseases s
The detection of viral pathogens in patients with severe pneumonia is not rare, and can be more common in certain group of patients. Invasive sampling for RT-PCR can be helpful, and such detection can lead to positive changes in clinical management.
Low-dose chest computed tomography (LDCT) screening increased detection of airway nodules. Most nodules appear to be secretions, but pathological lesions may show similar findings. The National Comprehensive Cancer Network (NCCN) recommends repeating LDCT after 1 month and proceeding to bronchoscopy if the nodules persist. However, no reports exist about incidentally detected airway nodules. We investigated the significance of airway nodules detected by LDCT screening.We screened patients with i
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