Korea University · 医学
Professor In Kim's research lab specializes in regenerative medicine and biomedical engineering, focusing on stem cell biology, tissue engineering, and gene therapy for neurological and dermatological disorders. Key research directions include the development of stem cell-derived therapies using transgene-free reprogramming, the application of bioactive factors and conditioned media to enhance tissue regeneration, and the design of injectable biomaterials for surgical adhesion prevention. The lab also investigates molecular mechanisms underlying cancer therapy response and rare disease modeling, with translational applications in hair regeneration, glioma treatment, and neural repair.
Figures are computed from collected data and may differ slightly.
Seven cases of fractures of the humerus from arm wrestling included 2 types of fractures. Two were spiral fractures of the humeral shaft with large butterfly fragments at the junction of the middle and distal one third caused by a violent uncoordinated muscular action. Five were fractures of the medial epicondyle of the humerus as a result of a sudden blow to the elbow. In all 7 cases, the fractures healed and arm function returned to normal.
Children with VPS are subject to multiple neuroimaging studies throughout their lifetime. Rapid sequence MRI is an effective alternative to CT while providing no ionizing radiation exposure or risk of developing radiation-induced cancer.
From January 1990 to December 1997, 53 Korean patients with chronic myeloid leukemia (CML) receiving bone marrow transplantation (BMT) from human leucocyte antigen (HLA)‐identical sibling donors conditioned with either busulfan and cyclophosphamide (BU/CY regimen) or total body irradiation and cyclophosphamide (TBI/CY regimen) were compared retrospectively. Transplantation‐related mortality was 19% in BU/CY and 12% in TBI/CY, and early death (<100 d) occurred in 3 patients conditioned with BU
The nanocluster-Si (nc-Si)/Er3+ interaction distance in Er-doped silicon nitride is investigated using SiOx/Si3N4:Er/Si3N4/Si3N4:Er multilayers. The composition and thickness of SiOx layers were fixed to provide constant sensitization, while the thickness of Si3N4:Er layers was varied to probe distance-dependence of sensitization. We find that while the distance over which an nc-Si transfers energy to an Er3+ ion is constant at ∼0.3 nm, the effective sensitization distance over which an Er3+ is
Abstract In this article, we studied the effect of hyaluronic acid (HA) on thermogelation of poly(caprolactone‐ b ‐ethylene glycol‐ b ‐caprolactone) (PCL‐PEG‐PCL) aqueous solution designed as an injectable system for prevention of postsurgical tissue adhesion. The PCL‐PEG‐PCL triblock copolymers were simply synthesized by ring‐opening polymerization of ε‐caprolactone (CL) in the presence of PEG as a polymeric initiator. The synthesized copolymers were confirmed by proton nuclear magnetic resonan
Arteriovenous fistula (AVF) involving the inferior mesenteric vessels is rare, and the affected patients usually present with abdominal pain, mass, or features of established portal hypertension. Colonic ischemia is a less common and more serious manifestation of AVF. We report a case of ischemic colitis secondary to inferior mesenteric AVF in a patient who underwent a previous liver transplantation, subsequently developed portal vein stenosis, and then presented with acute lower gastrointestina
We investigated the combined effects of p53 gene transfer and irradiation and its still unclear interaction mechanism in human gliomas. Four human glioma cell lines expressing mutant type p53 (U373 and A172) and wild-type p53 (D54MG and EFC-2) were transfected by adenoviral vectors bearing p53 gene at 50 multiplicity of infection. Two days after transfection, cells were irradiated (3, 6, and 9 Gy). The cytotoxicity was evaluated by clonogenic assay. The quantitative analysis of apoptosis and cel
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