Korea University · 医学
Professor Jae Myeong Lee's research lab focuses on translational biomedical research and advanced materials development, with a strong emphasis on clinical applications in critical care medicine and wearable energy technologies. The lab investigates trace element metabolism in critically ill patients to improve treatment outcomes, while also pioneering flexible, high-performance, and safe fiber-based batteries using novel fabrication techniques like biscrolling for wearable electronics. Additionally, the lab contributes to interventional radiology and surgical oncology, particularly in evaluating stent placement for vascular complications in transplant patients and the impact of bile spillage in gallbladder cancer surgery. These diverse yet interconnected research directions reflect a commitment to advancing patient care through innovative materials and clinical insights.
Figures are computed from collected data and may differ slightly.
We measured serum concentrations of trace elements and evaluated their clinical significance in relation to treatment outcomes of critically ill patients. A total of 167 participants (105 men and 62 women; average age, 61.4 years; age range, 18-90 years) were enrolled. Arterial blood concentrations of the trace elements zinc, copper, selenium, and manganese were measured every 14 days. At the time of intensive care unit (ICU) admission, serum concentrations of zinc, selenium, copper, and mangane
Flexible yarn- or fiber-based energy storing devices are attractive because of their small dimension, light weight, and suitability for integration into woven or textile application. Some Li-ion based yarn or fiber batteries were developed due to their performance advantages, realizing highly performing and practically safe wearable battery still remains a challenge. Here, high performance and safe yarn-based battery is demonstrated by embedding active materials into inner structure of yarn and
The aims of this study were to evaluate both the efficacy of stent placement for treating inferior vena cava (IVC) stenosis and the patency of hepatic veins (HVs) following IVC stent placement. Fourteen hepatic transplant recipients underwent stent placement to treat IVC stenosis. The median interval between transplantation and stent placement was 32 days. Stents varied from 20-36 mm in diameter and were 60-120 mm long. We retrospectively analyzed the technical and clinical success, changes of h
We determined the influence of bile spillage on recurrence and survival during laparoscopic cholecystectomy (LC) for gallbladder (GB) cancer. Among the 136 patients with GB cancer treated at Ajou University Hospital between 1994 and 2007, 28 underwent LC alone. We compared patients without bile spillage (bile spillage [-] group, n = 16) with patients who had bile spillage (bile spillage [+] group, n = 12). There was no statistical difference in stage between the groups. In the bile spillage (-)
Clinical Research Information Service, Republic of Korea (CRIS); KCT0000503 ; Registration date: Aug 13, 2012.
These findings suggest that lidocaine and procaine dose-dependently preserve endothelium-dependent vasorelaxation against ROS attack, potentially via hydrogen peroxide scavenging.
Metastasis of hepatocellular carcinoma (HCC) to the ovary is notably rare. We present a case of HCC metastasis to the ovary with a review of the literature, which includes only 7 reported cases. A 43-year-old hepatitis B virus carrier was admitted with a right ovarian cystic mass. She had been diagnosed with HCC 2 years prior, for which she underwent transarterial chemoembolization followed by right posterior sectionectomy. Eight months after the hepatectomy, the first intrahepatic recurrence wa
Cyber attacks targeting the Supervisory Control and Data Acquisition (SCADA) systems are becoming more complex and more intelligent. Currently proposed security measures for the SCADA systems come under three categories: physical/logical network separation, communication message security, and security monitoring. However, the recent malwares which were used successfully to disrupt the critical systems show that these security strategies are necessary, but not sufficient to defend these malwares.
A solid pseudopapillary tumor (SPT) is a pancreatic neoplasm of low malignant potential. The potentially malignant pathologic features of SPTs were regarded as angioinvasion, perineural invasion, deep invasion of the surrounding acinar tissue, and nuclear pleomorphism. We retrospectively reviewed 31 cases of SPTs (25 female and 6 male patients, with an average age of 35 ± 14 years). The mean follow-up period was 132.0 ± 55.9 months. To evaluate the clinical impact of above pathological parameter
NECs of the gallbladder are very aggressive tumors showing poor survival outcomes against current treatments. Further understanding on the clinical and pathologic characteristics of these NETs seems to be necessary to find more effective treatment modalities.
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