Ulsan National Institute of Science and Technology · 工学
Professor Jaesung Jang's research lab specializes in the development of advanced electrochemical biosensors for rapid, label-free detection of infectious pathogens and cardiac biomarkers. The lab focuses on integrating nanomaterials such as reduced graphene oxide, carbon nanotubes, and functionalized paper substrates with microfluidic and screen-printed electrode platforms to enable low-cost, portable, and highly sensitive diagnostic devices. Key research directions include the design of aptasensors and immunosensors for influenza viruses (H1N1, H5N1, H7N9, H9N2) and cardiac myoglobin, as well as innovative photocatalytic air disinfection systems using vacuum UV and Pd-TiO2 catalysts. The lab emphasizes practical applications in point-of-care diagnostics and environmental health, combining materials science, electrochemistry, and bioengineering.
Figures are computed from collected data and may differ slightly.
Reduced graphene oxide (RGO) has recently gained considerable attention for use in electrochemical biosensing applications due to its outstanding conducting properties and large surface area. This report presents a novel microfluidic chip integrated with an RGO-based electrochemical immunosensor for label-free detection of an influenza virus, H1N1. Three microelectrodes were fabricated on a glass substrate using the photolithographic technique, and the working electrode was functionalized using
Although many studies concerning the detection of influenza virus have been published, a paper-based, label-free electrochemical immunosensor has never been reported. Here, we present a cost-effective, handmade paper-based immunosensor for label-free electrochemical detection of influenza virus H1N1. This immunosensor was prepared by modifying paper with a spray of hydrophobic silica nanoparticles, and using stencil-printed electrodes. We used a glass vaporizer to spray the hydrophobic silica na
Acute myocardial infarction (AMI), also recognized as a "heart attack," is one leading cause of death globally, and cardiac myoglobin (cMb), an important cardiac biomarker, is used for the early assessment of AMI. This paper presents an ultrasensitive, label-free electrochemical aptamer-based sensor (aptasensor) for cMb detection using polyethylenimine (PEI)-functionalized reduced graphene oxide (PEI-rGO) thin films. PEI, a cationic polymer, was used as a reducing agent for graphene oxide (GO),
Many ultraviolet (UV)-based disinfection methods have been developed; however, these methods usually use the recirculating mode or need long irradiation periods due to its low photon energy. Vacuum UV (VUV) was recently found to be a promising light source, despite its ozone generation. In this study, we investigated photocatalysis reactions by VUV with short irradiation times (0.004–0.125 s) for simultaneously inactivating airborne MS2 viruses and degrading the generated ozone toward a flow-thr
Many studies have been conducted on measuring avian influenza viruses and their hemagglutinin (HA) antigens via electrochemical principles; most of these studies have used gold electrodes on ceramic, glass, or silicon substrates, and/or labeling for signal enhancement. Herein, we present a paper-based immunosensor for label-free measurement of multiple avian influenza virus (H5N1, H7N9, and H9N2) antigens using flexible screen-printed carbon nanotube-polydimethylsiloxane electrodes. These flexib
The influenza virus has received extensive attention due to the recent H1N1 pandemics originating from swine. This study reports a label-free, highly sensitive, and selective electrical immunosensor for the detection of influenza virus H1N1 based on dielectrophoretically deposited single-walled carbon nanotubes (SWCNTs). COOH-functionalized SWCNTs were deposited on a self-assembled monolayer of polyelectrolyte polydiallyldimethyl-ammonium chloride (PDDA) between two gold electrodes by dielectrop
Airborne influenza viruses are responsible for serious respiratory diseases, and most detection methods for airborne viruses are based on extraction of nucleic acids. Herein, vertical-flow-assay-based electrochemical paper immunosensors were fabricated to rapidly quantify the influenza H1N1 viruses in air after sampling with a portable electrostatic particle concentrator (EPC). The effects of antibodies, anti-influenza nucleoprotein antibodies (NP-Abs) and anti-influenza hemagglutinin antibodies
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