Yonsei University · 医学
Professor Jemin Kim's research lab specializes in translational biomedical research with a focus on dermatology, aging, and regenerative medicine. The lab investigates the gut-brain axis in relation to migraine and gastrointestinal disorders, explores the clinical efficacy of collagen peptides for skin rejuvenation and photoaging, and develops artificial intelligence models for objective scar assessment post-surgery. Additionally, the lab examines dermatological treatments for acne and related skin conditions, integrating clinical, biophysical, and imaging approaches.
Figures are computed from collected data and may differ slightly.
Migraine is a common disease worldwide, and recent studies showed that the incidence of migraine was increased in patients with gastrointestinal (GI) diseases. In addition, preclinical evidence suggested a bidirectional relationship between the GI nervous system and the central nervous system called the gut−brain axis. This study aimed to determine the association between several high-prevalence GI diseases and migraine. Patients diagnosed with migraine or GI diseases were classified as the pati
Orally administered collagen peptides could contribute to antiaging by replacing the degraded extracellular matrix proteins caused by photoaging. This study aimed to evaluate the efficacy and safety of low-molecular-weight collagen peptides for treating photoaged and dry skin. In this randomized, placebo-controlled, parallel-group, double-blinded trial, we randomly assigned study participants (<i>n</i> = 100) to either the test product group or placebo group at a 1:1 ratio for 12 weeks. The wrin
Evaluation of scar severity is crucial for determining proper treatment modalities; however, there is no gold standard for assessing scars. This study aimed to develop and evaluate an artificial intelligence model using images and clinical data to predict the severity of postoperative scars. Deep neural network models were trained and validated using images and clinical data from 1283 patients (main dataset: 1043; external dataset: 240) with post-thyroidectomy scars. Additionally, the performanc
FMR combined with AFL is a well-tolerated and effective treatment modality for inflammatory acne and acne scarring.
The purpose of this study was to investigate the vertical angular momentum generation strategies used by skilled ballet dancers in pirouette en dehors. Select kinematic parameters of the pirouette preparation (stance depth, vertical center-of-mass motion range, initial shoulder line position, shoulder line angular displacement, and maximum trunk twist angle) along with vertical angular momentum parameters during the turn (maximum momentums of the whole body and body parts, and duration and rate
The 0.5% silymarin-containing antioxidant formulation improved acne's clinical severity and related skin biophysical parameters.
Although combining allergen immunotherapy with biologics has shown promise in treating atopic diseases such as asthma and allergic rhinitis, atopic dermatitis (AD) remains notably underexplored in this context. This study aimed to investigate the efficacy and safety of combining dupilumab with subcutaneous immunotherapy (SCIT) for severe AD refractory to standard treatments. This was a single-center retrospective analysis assessing patients with severe AD treated with combined dupilumab and SCIT
In this paper, we present an approach to perform reasoning for scalable OWL ontologies in a Hadoop-based distributed computing cluster. Rule-based reasoning is typically used for a scalable OWL-Horst reasoning; typically, the system repeatedly performs many operations involving semantic axioms for big ontology triples until no further inferred data exists. Thus, the reasoning systems suffer from performance limitations when ontology reasoning is performed via disk-based MapReduce approaches. To
Combined treatment with low-dose isotretinoin and energy-based intervention is well tolerated and associated with positive responses in patients with inflammatory acne.
Our study findings suggest that injectable HA/MADM is a potentially effective and safe treatment option for treating HIV-positive patients with FLA.
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