Yonsei University · 工学
Professor Jinkee Hong's research lab specializes in the design and fabrication of advanced functional nanomaterials and multilayer thin films using layer-by-layer (LbL) assembly techniques. The lab focuses on developing smart, stimuli-responsive coatings for biomedical applications—particularly controlled drug delivery systems with sequential or programmable release of therapeutics—while also exploring applications in energy storage, microwave absorption, and nanodevices. Key innovations include the use of graphene-based materials (e.g., GO, rGO) and inorganic nanoparticles (e.g., ferrite) to engineer films with tunable electrical, mechanical, and degradation properties. The lab integrates materials science, nanotechnology, and biomedicine to create multifunctional platforms for healthcare and defense technologies.
Figures are computed from collected data and may differ slightly.
The ability to control the timing and order of release of different therapeutic drugs will play a pivotal role in improving patient care and simplifying treatment regimes in the clinic. The controlled sequential release of a broad range of small and macromolecules from thin film coatings offers a simple way to provide complex localized dosing in vivo. Here we show that it is possible to take advantage of the structure of certain nanomaterials to control release regimes from a scale of hours to m
We introduce a novel and versatile approach for preparing hollow multilayer capsules of graphene oxide nanosheets. Positively charged reduced graphene oxide (rGO-NH3+) and negatively charged reduced graphene oxide (rGO-COO−) were used as building blocks for the layer-by-layer assembly of graphene multilayer films onto polystyrene (PS) colloids. After removing the PS colloids with THF treatment, hollow graphene capsules with necessary physical and chemical stabilities were prepared successfully.
Over the past years, the layer-by-layer (LbL) assembly has been widely developed as one of the most powerful techniques to prepare multifunctional films with desired functions, structures and morphologies because of its versatility in the process steps in both material and substrate choices. Among various functional nanoscale objects, carbon-based nanomaterials, such as carbon nanotubes and graphene sheets, are promising candidates for emerging science and technology with their unique physical,
Recent research has highlighted degradable multilayer films that enable the programmed release of different therapeutics. Multilayers constructed by the layer-by-layer (LbL) deposition that can undergo disassembly have been demonstrated to be of considerable interest, particularly for biomedical surface coatings due to their versatility and mild aqueous processing conditions, enabling the inclusion of biologic drugs with high activity. In this study, we examine the controlled release of a protei
A method to control activation of a DNA nanodevice by supplying a complementary DNA (cDNA) strand from an electro-responsive nanoplatform is reported. To develop functional nanoplatform, hexalayer nanofilm is precisely designed by layer-by-layer assembly technique based on electrostatic interaction with four kinds of materials: Hydrolyzed poly(β-amino ester) can help cDNA release from the film. A cDNA is used as a key building block to activate DNA nanodevice. Reduced graphene oxides (rGOs) and
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