Kyung Hee University · 医学
Professor Kang-Il Kim's research lab specializes in regenerative medicine and orthopedic surgery, with a primary focus on mesenchymal stem cell therapy and cartilage regeneration in osteoarthritis. The lab investigates innovative, minimally invasive treatments such as intra-articular injection of autologous adipose-derived mesenchymal stem cells and the use of osteotomies—particularly medial open-wedge high tibial osteotomy—for structural and biological joint repair. Their work combines clinical trials with biomechanical and regenerative outcomes, emphasizing patient-centered results in knee and hip joint preservation. The lab also explores the synergistic effects of surgical correction and tissue regeneration, particularly in lower BMI patients with varus malalignment.
Figures are computed from collected data and may differ slightly.
Mesenchymal stem cells (MSCs) have been the focus of an emerging treatment for osteoarthritis. However, few studies reported about outcomes of an intra-articular injection of autologous adipose-derived mesenchymal stem cells (AD-MSCs). This study aimed to assess the efficacy and safety of a single intra-articular injection of AD-MSCs for patients with knee osteoarthritis. It was a prospective double-blinded, randomized controlled, phase IIb clinical trial. AD-MSCs were administered for 12 patien
This study replicated earlier work comparing reward allocation preferences across countries. Results obtained from student groups from the United States, Japan, and South Korea supported the earlie...
Therapeutic study, level V (expert opinion). See Guidelines for Authors for a complete description of levels of evidence.
NCT03990805 (ClinicalTrials.gov identifier).
Regeneration of degenerated articular cartilage in the medial compartment can be expected while correcting a varus deformity in arthritic knees after medial open-wedge HTO with a locked plate system without any additional cartilage regeneration procedures. Moreover, we suggest that medial open-wedge HTO in the medial arthritic knee with varus malalignment should be highly successful in terms of cartilage regeneration, especially for lower BMI patients.
Reconstructive acetabular osteotomy is a well established and effective procedure in the treatment of acetabular dysplasia. However, the dysplasia is frequently accompanied by intra-articular pathology such as labral tears. We intended to determine whether a concomitant hip arthroscopy with peri-acetabular rotational osteotomy could identify and treat intra-articular pathology associated with dysplasia and thereby produce a favourable outcome. We prospectively evaluated 43 consecutive hips treat
Level IV, therapeutic case series.
Therapeutic studies, level IV (case series). See the Guidelines for Authors for a complete description of levels of evidence.
These findings indicate that doxorubicin enhances transgene expression under the control of the CMV promoter and that doxorubicin might be used as an adjuvant to radioiodine therapy by NIS gene transfer in anaplastic thyroid carcinoma.
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