慶應義塾大学 · 医学
高abayashi教授の研究室は、炎症性腸疾患（UC）の内視鏡的診断支援に向けたAI開発や、UCに合併する結腸炎関連癌（UCAN）の内視鏡的所見の解明を進めています。また、胃がんに対するI-125線源を用いた低線量率放射線照射の効果を細胞系および動物モデルで評価し、がん治療の新たなアプローチを模索しています。特に、内視鏡的所見とがんの生物学的特性の関連性に注目した、臨床応用に直結する研究が特徴です。
Figures are computed from collected data and may differ slightly.
The AI developed here can diagnose UC severity endoscopically similar to IBD expert endoscopists.
endoscopic mucosal resection for a sporadic adenoma located at severe longitudinal ulcer scars in ulcerative colitis Fig.
When a characteristic mucosal pattern, such as a small round or mesh pattern, is found by DCE, the possibility of UCAN should be considered.
The efficacy of conventional radiation therapy for gastric cancer is controversial. In this study, we evaluated the in vitro and in vivo effects of continuous low-dose-rate irradiation by I-125 seeds on different histological types of gastric cancer cell lines. Three human gastric cancer cell lines (MKN74, MKN45, and NUGC4) were treated with or without continuous low-dose irradiation by I-125 seeds in vitro and in vivo. Cell viability, apoptosis, caspase-3 assay, and cell-cycle distribution were
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