慶應義塾大学 · 医学
Matsumoto教授の研究室では、画像診断の高度化を目的として、バリオメトリック・マルチスペクトル（VMS）CT技術の臨床的応用に注力しています。特に70keV程度のVMSイメージングが、従来の120kVpCTに比べて被曝線量を維持したまま画像ノイズを低減し、コントラスト対ノイズ比（CNR）を向上させることを実証しています。この技術は、標準的な体形の患者においても高品質な診断画像を提供可能であり、今後のCT診断の標準的アプローチの可能性を秘めています。
Figures are computed from collected data and may differ slightly.
VMS imaging at approximately 70 keV yielded lower image noise and higher CNR than did 120-kVp CT for a given radiation dose. VMS imaging has the potential to replace 120-kVp CT as the standard CT imaging modality, since optimal VMS imaging may be expected to yield improved image quality in a patient with standard body habitus.
Interleukin-15 (IL-15) is known to stimulate the proliferation of CD8(+) T-cells and natural killer cells, and also to help to maintain memory CD8(+) T cells, suggesting that it may be of value in cytokine treatment of bladder cancer. In this experiment, we tested the efficiency of intravesical liposomal IL-15 gene delivery and its antitumor effect in a mouse orthotopic bladder cancer model. We established an orthotopic bladder cancer model by implanting 5×10(5) MBT-2 cells into female C3H/HeN m
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