慶應義塾大学 · 医学
Kazuno Negishi教授の研究室では、視細胞の生体電気的応答と神経伝達物質の役割に注目し、魚の網膜におけるヒスタミンやカテコールアミンの影響を電気生理学的手法で解明しています。特に水平細胞の光応答に及ぼす神経調節のメカニズムを、光刺激と薬理学的介入を組み合わせて解析しています。また、人工観察レンズ（IOL）の光学的特性が網膜像質に与える影響についても、色収差の観点から研究を展開しています。
Figures are computed from collected data and may differ slightly.
The effects of catecholamines (CA) and certain related compounds in the superfusate were examined on the intracellularly recorded potential from horizontal cells in the fish (Eugerres plumieri) retina. The stimulated retinal area consisted of a central spot 1.0 mm in diameter and an annulus 2.0 mm in inner diameter and 4.0 mm in outer diameter; both forms of monochromatic stimuli were centered relative to the recording microelectrode. Each of the CA (dopamine, noradrenaline, and adrenaline) prod
Our results showed that longitudinal chromatic aberrations of some IOLs may degrade the quality of the retinal image. Attention must be paid to the detailed optical performance of IOL materials to achieve good visual function.
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