大阪大学 · 医学
Yamashita教授の研究室は、食道がんや膵がんをはじめとする消化器がんの治療戦略に焦点を当てており、再発後の予後を改善するための多モodal治療や、リンパ節郭清の最適化、術後合併症の予測因子の同定を進めています。特に、肺転移やリンパ節再発に対する局所治療の有効性や、術前口腔内細菌検査による肺炎予測といった、臨床的実用性の高い研究が特徴です。
Figures are computed from collected data and may differ slightly.
Although the prognosis of recurrent esophageal cancer remains unfavorable, if multimodal treatment that includes local therapy was curative, prognosis could improve, especially in patients with lymph node or lung recurrence.
Patients with first recurrence of PDAC as pulmonary metastasis had a better prognosis than patients with other types of metastases. Moreover, when isolated pulmonary metastasis is controlled for a certain period, pulmonary resection is likely to improve patient survival.
Preoperative oropharyngeal culture is a simple and low-cost method that can predict both the occurrence of postoperative pneumonia and poor prognosis after esophagectomy.
Although 3-field lymph node dissection (3-FLD) is often performed for thoracic esophageal squamous cell carcinoma (ESCC), the clinical effects of cervical lymph node dissection in addition to mediastinal and abdominal dissections on postoperative complications remain unclear. A total of 367 ESCC patients who underwent curative esophagectomy for thoracic esophageal cancer in our hospital from 2010 to 2015 were included in the study: 157 patients who underwent 2-field lymph node dissection (2-FLD)
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