Yonsei University · 医学
Professor Kyoung-Tak Kang's research lab specializes in computational biomechanics and regenerative medicine, with a focus on patient-specific orthopedic implant design and cartilage tissue engineering. The lab integrates medical imaging, finite element analysis, and mechano-regulation theory to optimize implant mechanics and scaffold properties for improved joint function and regeneration. Key research directions include kinematic and mechanical alignment in total knee arthroplasty, femoral component positioning, and the development of drug-eluting microspheres for cartilage repair.
Figures are computed from collected data and may differ slightly.
The development of successful scaffolds for bone tissue engineering requires concurrent engineering that combines different research fields. In previous studies, phenomenological computational models predicted the mechanical properties of a scaffold in a simple loading condition using the mechano-regulation theory. Therefore, the aim of this study is to predict the mechanical properties of an optimum scaffold required for cartilage regeneration using three-dimensional knee joint developed from m
This article used probabilistic analysis to evaluate material properties of the in vivo subject-specific tibiofemoral (TF) joint model. Sensitivity analysis, based on a Monte Carlo (MC) method, was performed using a subject-specific finite element (FE) model generated from in vivo computed tomography (CT) and magnetic resonance imaging (MRI) data, subjected to two different loading conditions. Specifically, the effects of inherent uncertainty in ligament stiffness, horn attachment stiffness, and
Anatomic TBR and FBR for grade III PLC injuries could restore better biomechanics in the knee joint compared with nonanatomic reconstruction. However, discrepancy with the normal condition requires further modification of surgical techniques.
A surgeon should be prudent in terms of determining the PTS because an excessive increase in the PTS may lead to the progressive loosening of the TF joint due to a reduction in collateral ligament tension and failure of the post in a PE insert. Thus, we support a more individualized approach of optimal PTS determination given the findings of the study.
(1) Background: Although knee arthroplasty or knee replacement is already an effective clinical treatment, it continues to undergo clinical and biomechanical improvements. For an increasing number of conditions, prosthesis based on an individual patient's anatomy is a promising treatment. The aims of this review were to evaluate the clinical and biomechanical efficacy of patient-specific knee prosthesis, explore its future direction, and summarize any published comparative studies. (2) Methods:
HTO should be performed while considering a medial opening wedge HTO to avoid a type II and type III LHF as a potential complication.
The wear of tibial inserts in total knee arthroplasty (TKA) remains a major limitation of longevity. However, wear tests are expensive and time-consuming. Computational wear prediction using a finite-element (FE) model followed by validation through comparison with experimental data is effective for assessing new prosthetic designs or materials prior to functional testing and surgical implementation. In this study, the kinematics, volumetric wear, and wear depth of tibial inserts made of differe
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