九州大学 · 医学
福井正紀教授の研究室は、股関節形成症(DDH)の病態メカニズムに着目し、特に骨盤全体の構造異常と関節内病変の進行に関する解剖学的・臨床的解析を進めています。特に、前方上部の臼蓋部における軟骨・円板の変性が痛みの早期発現や関節炎進行と関連することを明らかにしており、人工関節置換術の早期化を防ぐための手術的治療戦略の確立を目指しています。
Figures are computed from collected data and may differ slightly.
In patients with developmental dysplasia of the hip, acetabular retroversion results from relatively deficient coverage by the posterior portion of the acetabulum. Developmental dysplasia with acetabular retroversion is associated with an earlier onset of pain than is developmental dysplasia with anteversion, suggesting a correlation between deficiency of the posterior acetabular wall and the earlier onset of pain.
Our observations suggest structural abnormalities exist throughout the pelvis in DDH, and the morphologic abnormalities of the acetabulum are not caused solely by local dysplasia around the hip, but are influenced by the morphologic features of the entire pelvis.
The incidence of intraarticular lesions in developmental dysplasia of the hip was high, even in the prearthritic stage. These lesions tended to originate in the anterosuperior area of the acetabulum and were generally progressive.
In order to clarify how intra-articular lesions influence the survival of a periacetabular osteotomy in patients with dysplasia of the hip, we performed an observational study of 121 patients (121 hips) who underwent a transposition osteotomy of the acetabulum combined with an arthroscopy. Their mean age was 40.2 years (13 to 64) and the mean follow-up was 9.9 years (2 to 18). Labral and cartilage degeneration tended to originate from the anterosuperior part of the acetabulum, followed by the fe
Level IV, diagnostic study. See the Guidelines for Authors for a complete description of levels of evidence.
Abstract Measurements of light scatting, sedimentation equilibrium, sedimentation velocity, and viscosity were carried out on fractions of native amylose in dimethylsulfoxide at 25°C. The data for statistical radius as a function of weight‐average molecular weight M w suggested a stiff nature of this biopolymer in the solvent studied when interpreted in terms of Kirste's recent calculations with a stiff chain model. The data for sedimentation coefficient were consistent with this suggestion, and
Level IV, diagnostic study.
Level III, diagnostic study.
<i>Objectives.</i> To determine the minimum lateral bone coverage required for securing stable fixation of the porous-coated acetabular components (cups) in hip dysplasia. <i>Methods.</i> In total, 215 primary total hip arthroplasties in 199 patients were reviewed. The average follow-up period was 49 months (range: 24-77 months). The lateral bone coverage of the cups was assessed by determining the cup center-edge (cup-CE) angle and the bone coverage index (BCI) from anteroposterior pelvic radio
Our findings suggest that TOA with structural bone allografting is a viable surgical option for correcting severely dysplastic acetabulum in adolescents and young adults without advanced osteoarthritis, with favourable mid-term outcomes.
Abstract Laser-induced desorption and ionization (LDI) of gold ions (Aun+: n = 1–3) were observed from gold nanorods in a liver tissue section (thickness: 10 µm). Larger amounts of gold nanorods produced stronger mass signals. Organic molecules in the tissue were not detected and did not inhibit the LDI processes of the gold nanorods in the tissue. Because of the selective LDI processes of the gold nanorods, the distribution of gold in the liver was successfully determined by imaging mass spectr
Level IV, therapeutic study.
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