Seoul National University · 医学
Professor Min Woo Kang's research lab specializes in clinical nephrology and predictive analytics in kidney disease, focusing on improving outcomes for patients with acute and chronic kidney injury. The lab employs advanced machine learning techniques to develop and validate predictive models for critical complications such as hypotension during continuous renal replacement therapy (CRRT), end-stage renal disease progression, and mortality risk. A key research direction involves validating and recalibrating existing risk prediction tools—like the Kidney Failure Risk Equation—for diverse populations, including Korean cohorts, to enhance clinical decision-making. The lab also investigates novel biomarkers and physiological markers, such as hyperuricemia and glomerular hyperfiltration, in relation to renal and systemic outcomes including dementia.
Figures are computed from collected data and may differ slightly.
Machine learning algorithms increase the accuracy of mortality prediction for patients undergoing CRRT for acute kidney injury compared with previous scoring models.
Hypotension after starting continuous renal replacement therapy (CRRT) is associated with worse outcomes compared with normotension, but it is difficult to predict because several factors have interactive and complex effects on the risk. The present study applied machine learning algorithms to develop models to predict hypotension after initiating CRRT. Among 2349 adult patients who started CRRT due to acute kidney injury, 70% and 30% were randomly assigned into the training and testing sets, re
Hyperuricemia increases the risks of AKI and all-cause mortality in hospitalized patients.
Predicting the risk of end-stage renal disease (ESRD) progression facilitates appropriate nephrology care of patients with chronic kidney disease (CKD). Previously, the kidney failure risk equations (KFREs) were developed and validated in several cohorts. The purpose of this study is to validate the KFREs in a Korean population and to recalibrate the equations. A total of 38,905 adult patients, including 13,244 patients with CKD stages G3-G5, who were referred to nephrology were recruited. Using
Glomerular hyperfiltration may be associated with dementia. In this respect, subjects with glomerular hyperfiltration should be monitored more closely for signs and symptoms of dementia.
Abstract Background: Hypotension after starting continuous renal replacement therapy (CRRT) is associated with worse outcome, but it is difficult to predict because several factors have interactive and complex effects on the risk. The present study applied machine learning algorithms to develop models to predict hypotension after initiating CRRT. Methods: Among 2,349 adult patients who started CRRT due to acute kidney injury, 70% and 30% were randomly assigned into the training and testing sets,
In patients with chronic kidney disease (CKD), coronavirus disease 2019 (COVID-19) has a higher mortality rate than the general population; therefore, prevention is vital. To prevent COVID-19 infection, it is important to study individuals' risk aversion behavior. The objective of this study was to understand how the behavioral characteristics of physical distancing, hygiene practice, and exercise changed in patients with CKD during the COVID-19 pandemic and to identify the characteristics of pa
Purpose: To evaluate the severity of trauma, many scoring systems and predictive models have been presented. The quick Sequential Organ Failure Assessment (qSOFA) is a simple scoring system based on vital signs, and we expect it to be easier to apply to trauma patients than other trauma assessment tools. methods: This study was a cross-sectional study of trauma patients who visited the emergency department of Jeju National University Hospital. We excluded patients under the age of 18 years and u
This study provides population-scale evidence from general health screening participants, encouraging the prompt initiation of antihypertensive medication to reduce the risk of adverse outcomes. Delayed consideration of medication in primary health screenings may be associated with higher risks of MI, stroke, and death.
Patients with positive blood cultures in the intensive care unit (ICU) are at high risk for septic acute kidney injury requiring continuous kidney replacement therapy (CKRT), especially when treated with vancomycin. This study developed a machine learning model to predict CKRT and examined vancomycin's impact using deep learning-based causal inference. We analyzed ICU patients with positive blood cultures, utilizing the Medical Information Mart for Intensive Care III data set. The primary outcom
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