Mitsuhiko Shionoya

DNA has a structural basis to array functionalized building blocks. Here we report the synthesis of a series of artificial oligonucleotides, d(5'-GH(n)C-3') (n = 1 to 5), with hydroxypyridone nucleobases (H) as flat bidentate ligands. Right-handed double helices of the oligonucleotides, nCu2+.d(5'-GH(n)C-3')2 (n = 1 to 5), were quantitatively formed through copper ion (Cu2+)-mediated alternative base pairing (H-Cu2+-H), where the Cu2+ ions incorporated into each complex were aligned along the he

Over the past few decades, supramolecular chirality in discrete metallosupramolecular architectures has received considerable attention. In this review, a comprehensive summary of discrete, chiral coordination-driven structures, including helices, metallacycles, metallocages, etc., is presented. Although chirality can be introduced prior to, during or even after the coordination self-assembly process, this review puts major emphasis on the more recent development of metallosupramolecular archite

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiprotonated sapphyrin: a fluoride selective halide anion receptorMitsuhiko Shionoya, Hiroyuki Furuta, Vincent Lynch, Anthony Harriman, and Jonathan L. SesslerCite this: J. Am. Chem. Soc. 1992, 114, 14, 5714–5722Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July 1992https://pubs.acs.org/doi/10.1021/ja00040a034https://doi.org/10.1021/ja00040a034research-articleACS PublicationsRequest reuse permiss

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel "Multipoint" Molecular Recognition of Nucleobases by a New Zinc(II) Complex of Acridine-Pendant Cyclen (Cyclen = 1,4,7,10-Tetraazacyclododecane)Mitsuhiko Shionoya, Takuya Ikeda, Eiichi Kimura, and Motoo ShiroCite this: J. Am. Chem. Soc. 1994, 116, 9, 3848–3859Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 May 1994https://pubs.acs.org/doi/10.1021/ja00088a021https://doi.org/10.1021/ja00088a021r

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA new ternary zinc(II) complex with [12]aneN4 (=1,4,7,10-tetraazacyclododecane) and AZT (=3'-azido-3'-deoxythymidine). Highly selective recognition of thymidine and its related nucleosides by a zinc(II) macrocyclic tetraamine complex with novel complementary associationsMitsuhiko Shionoya, Eiichi Kimura, and Motoo ShiroCite this: J. Am. Chem. Soc. 1993, 115, 15, 6730–6737Publication Date (Print):July 1, 1993Publication History Published online1 May 200

Bridging the gap: The electrical conductance of individual metallo-DNA duplexes that bridge a carbon nanotube gap can be measured and switched by use of Cu2+ ions (see picture, yellow sphere: Cu2+). These studies form the basis for new exciting research that interfaces molecular nanodevices with biological systems.

Neatly wrapped up: alternately stacked square-planar platinum(II) complexes inside a dinuclear coordination cage were prepared to give a discrete and soluble Pt(5) -array of the Magnus' salt type. Characterization of the complex in solution was complemented by an X-ray crystal structure of {[Pt(pyridine)(4)]⋅ [PtCl(4)](2) @Cage}; this structure showed the linear, pentanuclear array within the cages and their circular packing into a hollow tubular superstructure.

Allosteric regulation is gaining increasing attention as a basis for the production of stimuli-responsive materials in many research areas including DNA nanotechnology. We expected that metal-mediated artificial base pairs, consisting of ligand-type nucleotides and a bridging metal ion, could serve as allosteric units that regulate the function of DNA molecules. In this study, we established a rational design strategy for developing Cu^II-responsive allosteric DNAzymes by incorporating

Please let me in! A new kind of (pseudo)rotaxane is formed quantitatively when a bis-anionic thread is added to a molecular cage comprised of two positively charged metal complexes. The rotaxanation mechanism follows two alternative ways depending on the metal (Pd vs. Pt) and the stopper size of the guest (see figure).

Guests welcome: Complex formation between AgI ions and a Zn-porphyrin ligand (L) possessing four 2,2′-bipyridyl groups produced a dimeric complex [Ag4L2]4+, wherein the interplane distance between the Zn-porphyrin groups was ideal for intercalation of aromatic molecules through π–π interactions. The cofacial dimer [Ag4L2]4+ serves as an excellent receptor for π-electron-deficient guests. As a service to our authors and readers, this journal provides supporting information supplied by the authors

Brücken schlagen: Die elektrische Leitfähigkeit einzelner die Lücke zwischen zwei Kohlenstoffnanoröhren überbrückender Metallo-DNA-Duplexe kann gemessen und durch den Einbau von Cu2+-Ionen (gelbe Kugel im Bild) geschaltet werden. Diese Ergebnisse bilden die Grundlage für Studien an der Schnittstelle zwischen molekularen Nanobauteilen und biologischen Systemen. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not c

Construction of a self-assembled cage complex through three different Zn(II) centers is achieved using a Zn porphyrin ligand with four 2,2'-bipyridin-5-yl (bpy) groups. The multiporphyrin cage encapsulates guest molecules unsymmetrically by π-π interactions. Well-balanced aqueous conditions, which allow the formation of both tris(bpy) and hydrated bis(bpy) Zn(II) units, result in the unsymmetrical yet well-defined supramolecular structure.