慶應義塾大学 · 医学
Murat Doğru教授の研究室では、ドライアイの根本的メカニズム解明に向け、マイボーム腺機能不全（MGD）の病態と酸化的な損傷が眼表面に与える影響を、分子・細胞レベルから解明しています。特に、酸化ストレスが角膜・結膜上皮に及ぼす影響や、そのバイオマーカーの同定、ならびに抗酸化物質を用いた治療戦略の検討が進んでいます。また、非侵襲的診断法（例：ストリップメニスコメトリー）の開発や、治療反応の客観的評価にも注力しています。
Figures are computed from collected data and may differ slightly.
DOI:10.1167/iovs.10-6997a Investigative Ophthalmology & Visual Science, Special Issue 2011, Vol. 52, No. 4 Copyright 2011 The Association for Research in Vision and Ophthalmology, Inc. 1922 ドライアイ疾患の原因としては、マイボーム腺機能不全 (MGD)がおそらく最も多い。この疾患によって数百万人 もの健康と幸福が損なわれているにもかかわらず、MGD の定 義、分類、診断、治療について世界的なコンセンサスはない。 そうしたコンセンサスに達する目的で、非営利団体である Tear Film and Ocular Surface Society( TFOS; http://www. tearfilm.org)が International Workshop on Meibomian Gland Dysfunction(国際マイボーム腺機能不全ワークショップ、 www.tearfilm.org/mgdwork
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