東京大学 · 生化学・遺伝学・分子生物学
Naoki Sato教授の研究室では、植物や藻類の細胞小器官、特にプラストドとミトコンドリアの遺伝子複製と膜脂質の代謝に注目した基礎生命科学研究を展開しています。特に、赤藻類のCyanidioschyzon merolaeをモデル生物として、細胞小器官内での脂質合成経路やDNA結合タンパク質の分子機構を遺伝子・タンパク質レベルで解明しています。また、環境要因に応じた脂肪酸不飽和度の変化や、気象システムにおける波動の伝播機構についても、地球規模の環境変動と関連づけて研究しています。
Figures are computed from collected data and may differ slightly.
Abstract Statistical features of quasi-stationary planetary waves were examined on the subtropical jet in the midsummer Northern Hemisphere by using objectively analyzed data and satellite data. As a result, a quasi-stationary wave train that is highly correlated with the midsummer climate over Japan was identified. A clear phase dependency of the appearance of waves was also confirmed. An analysis of temporal evolution and wave activity flux revealed that the eastward propagation of the wave pa
The acyl lipids making up the plastid membranes in plants and algae are highly enriched in polyunsaturated fatty acids and are synthesized by two distinct pathways, known as the prokaryotic and eukaryotic pathways, which are located within the plastids and the endoplasmic reticulum, respectively. Here we report the results of biochemical as well as genomic analyses of lipids and fatty acids in the unicellular rhodophyte Cyanidioschyzon merolae. All of the glycerolipids usually found in photosynt
Plastid nucleoids are known to bind to the envelope membrane in developing chloroplasts. Here, plastid DNA is extensively replicated. We previously detected a DNA binding protein in the inner envelope membranes of developing plastids in pea and named it PEND (for plastid envelope DNA binding) protein. In this study, we report on the structure and molecular characterization of a cDNA for the PEND protein. As a result of screening cDNA libraries in lambdagt11 with one of the target sequences of th
Plastids and mitochondria possess their own genomes. Although the replication mechanisms of these organellar genomes remain unclear in photosynthetic eukaryotes, several organelle-localized enzymes related to genome replication, including DNA polymerase, DNA primase, DNA helicase, DNA topoisomerase, single-stranded DNA maintenance protein, DNA ligase, primer removal enzyme, and several DNA recombination-related enzymes, have been identified. In the reference Eudicot plant Arabidopsis thaliana, t
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