Sungkyunkwan University · 材料科学
Professor Oh Seok Kwon's research lab specializes in the development of advanced nanomaterials and bioelectronic devices for biomedical and environmental sensing applications. The lab focuses on designing flexible, high-sensitivity sensors using conductive polymers and graphene-based nanomaterials, with a strong emphasis on molecular recognition and real-time detection of biological and chemical analytes. Key research directions include the integration of nanomaterials with biological receptors and aptamers for next-generation biosensors, as well as the engineering of nanostructured surfaces to enhance sensing performance. The lab also pioneers artificial sensory systems, such as multiplexed bioelectronic noses and liquid-gated field-effect transistors, to mimic human sensory functions.
Figures are computed from collected data and may differ slightly.
Graphene-based field-effect transistors (FETs) have been developed rapidly and are currently considered as an alternative for postsilicon electronics. In this study, polypyrrole-converted nitrogen-doped few-layer graphene (PPy-NDFLG) was grown on Cu substrate by chemical vapor deposition combined with vapor deposition polymerization and then transferred onto a flexible substrate. Furthermore, antivascular endothelial growth factor (VEGF) RNA aptamer conjugated PPy-NDFLG was integrated into a liq
One of the recently emerging topics in biotechnology is natural receptors including G protein-coupled receptors, ligand-gated ion channels, enzyme-linked receptors, and intracellular receptors, due to their molecular specificity. These receptors, other than intracellular receptors, which are membrane proteins expressed on the cell membrane, can detect extracellular stimuli. Many researchers have utilized cells with natural receptors embedded in the cellular membrane for human sense-mimicking pla
Tailoring the morphology of materials in the nanometer regime is vital to realizing enhanced device performance. Here, we demonstrate flexible nerve agent sensors, based on hydroxylated poly(3,4-ethylenedioxythiophene) (PEDOT) nanotubes (HPNTs) with surface substructures such as nanonodules (NNs) and nanorods (NRs). The surface substructures can be grown on a nanofiber surface by controlling critical synthetic conditions during vapor deposition polymerization (VDP) on the polymer nanotemplate, l
Early diagnosis of tumor malignancy is crucial for timely cancer treatment aimed at imparting desired clinical outcomes. The traditional fluorescence-based imaging is unfortunately faced with challenges such as low tissue penetration and background autofluorescence. Upconversion (UC)-based bioimaging can overcome these limitations as their excitation occurs at lower frequencies and the emission at higher frequencies. In this study, multifunctional silica-based nanocapsules were synthesized to en
Human sensory-mimicking systems, such as electronic brains, tongues, skin, and ears, have been promoted for use in improving social welfare. However, no significant achievements have been made in mimicking the human nose due to the complexity of olfactory sensory neurons. Combinational coding of human olfactory receptors (hORs) is essential for odorant discrimination in mixtures, and the development of hOR-combined multiplexed systems has progressed slowly. Here, we report the first demonstratio
In recent years, conducting polymer (CP) nanomaterials have been used in a variety of fields, such as in energy, environmental, and biomedical applications, owing to their outstanding chemical and physical properties compared to conventional metal materials. In particular, nanobiosensors based on CP nanomaterials exhibit excellent performance sensing target molecules. The performance of CP nanobiosensors varies based on their size, shape, conductivity, and morphology, among other characteristics
The necessity of managing stress levels is becoming increasingly apparent as the world suffers from different kinds of stresses including the extent of pandemic, the corona virus disease 2019 (COVID-19). Cortisol, a clinically confirmed stress hormone related to depression and anxiety, affects individuals mentally and physically. However, current cortisol monitoring methods require expert personnel, large and complex machines, and long time for data analysis. Here, we present a flexible and wear
Large-scale FET-type graphene micropattern (GM) nano-biohybrid-based immunosensor (GMNS) is fabricated in a controlled fashion to detect human immunodeficiency virus 2 antibody. Flexible GMNS shows a highly sensitive response and excellent mechanical bendability. The flexible GMNS in fluidic systems also has a stable response. This is the first experimental demonstration of a large-scale flexible fluidic FET-type immunoassay based on GM nano-biohybrids.
This study reports the first successful nanoscale encapsulation of triplet-triplet annihilation upconversion (TTA-UC) medium within a rigid silica shell using a self-assembly microemulsion process. These newly synthesized nanocapsules present a few critical advances that could be instrumental for a wide range of aqueous-based photonics applications, including photocatalysis, artificial photosynthesis, and bioimaging. The nanocapsules form a homogeneous suspension that can produce intense, diffus
We provide a review of the progress in materials and applications of TTA-UC: biological, environmental/energy, OLED, and other applications. Moreover, an excellent demonstration of TTA-UC based technologies are presented in each chapter.
Herein, 3D nanohybrid architectures consisting of MnO(x) nanocrystals, carbon nanofibers (CNFs), and graphene sheets are fabricated. MnO(x) -decorated CNFs (MCNFs) with diameters of about 50 nm are readily obtained via single-nozzle co-electrospinning, followed by heat treatment. The MCNFs are then intercalated between graphene sheets, yielding the ternary nanohybrid MCNF/reduced graphene oxide (RGO). This straightforward synthesis process readily affords product on a scale of tens of grams. The
Polypyrrole nanoparticles (PPyNPs) with uniform diameters of 20, 60, and 100 nm were fabricated by chemical oxidation polymerization. The synthesized PPyNPs provided higher conductivity and surface-to-volume ratio value in the order of 20 nm > 60 nm > 100 nm. The conductivities and BET surface areas were measured to be ca. 101 S cm−1/144 m2 g−1 (20 nm in diameter), ca. 10° S cm−1/104 m2 g−1 (60 nm in diameter), and ca. 10−1 S cm−1/68 m2 g−1 (100 nm in diameter). To minimize the contact resistanc
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