Kyung Hee University · 歯学
Professor Ok Hyung Nam's research lab specializes in regenerative dentistry and biomaterials, focusing on tissue engineering and clinical applications in oral and maxillofacial surgery. The lab investigates bioactive materials such as hyaluronic acid films and dental cements (e.g., TheraCal LC, MTA) to enhance wound healing, pulp regeneration, and bone age estimation using imaging. Key research directions include molecular mechanisms of inflammation and cell signaling (e.g., NF-κB, MAPK pathways) in dental pulp cells, and the development of 3D-printed surgical models to improve clinical training and outcomes.
Figures are computed from collected data and may differ slightly.
Results showed that our proposed method can estimate bone age by lateral cephalogram with sufficiently high accuracy.
Within the limits of this study, HA film was found to be effective for oral wound healing, particularly for re-epithelialization. This finding suggests that HA film delivery can be beneficial not only for clinical convenience but also for promoting oral wound healing.
G-Rb1 suppressed the LPS-induced increase of cell adhesion molecules and inflammatory cytokines, while also inhibiting PI3K/Akt, phosphorylation of NF-κB transcription factors, ERK and JNK of MAPK signalling in hDPCs.
A 3D-printed model for surgical extraction of a SNT can improve surgical skill and, especially, shorten the learning curve in beginners.
Within the limits of this study, hyaluronic acid film outperformed gels in terms of palatal wound healing in both models.
Pulp capping material should facilitate hard tissue regeneration on the injured pulp tissue. TheraCal LC (TC) was recently developed. Although TC has shown reliable clinical outcomes after direct pulp capping, there are still remaining concerns regarding its detrimental effect on pulp cells. Therefore, this study aimed to identify the gene expression of human deciduous tooth-derived dental pulp cells exposed to TC compared to mineral trioxide aggregate (MTA). The cells were cultured and exposed
This study aimed to evaluate the feasibility of a 3-dimensional (3D) planned surgical guide technique designed for impacted supernumerary teeth (STs) extraction using 3D printed simulation models. In total, 17 participants from two university hospitals were recruited. Each participant performed surgery with both the conventional and surgical guide techniques. The following parameters were evaluated: (1) The time required for ST extraction, (2) the area of the window opening, and (3) the volume o
This study evaluated the feasibility of a tooth preparation guide for prefabricated zirconia crowns (PZCs). Three-dimensional surface data for PZCs of the left maxillary primary first molar and left mandibular primary second molar were obtained using a model scanner. The tooth preparation data were digitally designed to harmonize with the adjacent teeth on the mixed dentition model and visualized using a color-coded map, which presents the required amount of tooth reduction. Twenty participants
The direction of mesiodens and the eruption period of adjacent permanent incisors affected the complication rate. The positional relationship between mesiodens and adjacent permanent central incisors had the strongest influence on both eruption disturbance and displacement of permanent central incisors.
In conclusion, doxycycline improved the periodontal healing of replanted teeth stored for 60 minutes in HBSS, whereas doxycycline did not improve periodontal healing of replanted tooth after 5 minutes of dry storage. Within the limits of this study, doxycycline showed more favorable periodontal healing despite delayed replantation.
Within the limits of this study, limited mouth opening hardly influenced the accuracy of intraoral scanning.
Compared to those in milk, genes in HBSS were differentially expressed with increasing storage duration, suggesting that diverse and different gene expression may be involved in HBSS and milk. However, a more detailed functional analysis of these differentially expressed genes in storage solutions should be performed in the future.
Ectopic eruption of permanent maxillary first molar can cause root resorption of adjacent primary second molar, thus leading to early loss of primary maxillary second molar. Therefore, it is necessary to correct ectopic maxillary first molar. This case report demonstrates that K-loop can be used as a simple, comfortable, and easier method to correct ectopic eruption of permanent maxillary first molar in existing severe root resorption on adjacent primary second molar.
This study aimed to evaluate the effects of tea extracts on oral biofilm colonization depending on steeping temperature. <i>S. mutans</i> and <i>S. sobrinus</i> were cultured and treated with green or black tea extracts prepared under different steeping conditions. Biofilm formation, glucosyltransferase (GTF) levels, bacterial growth, and acidogenicity were evaluated. Biofilms were also assessed by gas chromatography-mass spectrometry and confocal laser scanning microscopy. All extracts with hot
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