Seoktae Kang
Korea Advanced Institute of Science and Technology 건설환경공학부 · 環境科学
Seoktae Kang 교수의 연구실은 나노소재의 생물학적 영향과 환경 응용을 중심으로 연구를 진행하고 있습니다. 특히 탄소 나노튜브와 같은 나노소재가 박테리아에 미치는 세포막 손상 기반의 세균독성 메커니즘을 규명하며, 나노소재의 물리화학적 특성과 생체 상호작용 간의 관계를 규명하고자 합니다. 또한, 수처리 막의 생물오염 방지 및 중금속 제거를 위한 나노복합재료 개발 등 환경 정화 응용에도 초점을 맞추고 있습니다.
Figures are computed from collected data and may differ slightly.
We provide the first evidence that the size (diameter) of carbon nanotubes (CNTs) is a key factor governing their antibacterial effects and that the likely main CNT-cytotoxicity mechanism is cell membrane damage by direct contact with CNTs. Experiments with well-characterized single-walled carbon nanotubes (SWNTs) and multiwalled carbon nanotubes (MWNTs) demonstrate that SWNTs are much more toxic to bacteria than MWNTs. Gene expression data show that in the presence of both MWNTs and SWNTs, Esch
Rational modification of carbon nanotubes (CNTs) to isolate their specific physical and chemical properties will inform a mechanistic understanding of observed CNT toxicity in bacterial systems. The present study compares the toxicity of commercially obtained multiwalled carbon nanotubes (MWNTs) before and after physicochemical modification via common purification and functionalization routes, including dry oxidation, acid treatment functionalization, and annealing. Experimental results support
This study evaluates the cytotoxicity of four carbon-based nanomaterials (CBNs)--single-walled carbon nanotubes (SWNTs), multiwalled carbon nanotubes (MWNTs), aqueous phase C60 nanoparticles (aq-nC60), and colloidal graphite--in gram negative and gram positive bacteria. The potential impacts of CBNs on microorganisms in natural and engineered aquatic systems are also evaluated. SWNTs inactivate the highest percentage of cells in monocultures of Escherichia coli, Pseudomonas aeruginosa, Bacillus
We developed a method for preparing live bacterial cell probes for atomic force microscopy (AFM) using a bioinspired polydopamine wet adhesive. Microscopic examinations with bacterial and yeast cells indicated that cells were successfully glued to the end of the AFM cantilevers and remained viable for the duration of the force measurements. Interaction forces measured with live single-cell microorganism probes differed markedly from those obtained with glutaraldehyde-fixed microorganism probes.
Abstract The biofouling potential is one of the important factors to design and to select membranes for water and wastewater treatment. In this investigation, the effect of membrane surface properties during the attachment of S. cerevisiae cells was examined using a laboratory‐scale membrane filtration cell enabling direct microscopic observation of microbial cell deposition. The experimental results from 6 commercially available membranes showed that the initial adhesion rate, k d , was affecte
In this study, expanded graphite (EG) was decorated with manganese oxide nanoparticles (MONPs) by the hydrothermal method, and the newly formed composite (MONPs-EG) was applied as adsorbent for the removal of heavy metals from aqueous solutions. The comparative and competitive adsorption of Pb2+ and Ni2+ (0.01–1.00 mM) on MONPs-EG was investigated. Data from isothermal adsorption of single and binary systems suggested that both Pb2+ and Ni2+ were well described by the Langmuir isotherm, and the
Hydraulically irreversible membrane fouling is a major problem encountered during membrane-based water purification. Membrane foulants present large hydrophobic fractions, with humic acid (HA) being a prevalent example of hydrophobic natural organic matter. Furthermore, HA contains numerous aromatic rings (π electrons), and its hydrophobic interactions are a major cause of irreversible membrane fouling. To address this issue, in this study, we used the cation-π interaction, which is a strong non
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