Seoul National University · 医学
Professor Seong Jin Jo's research lab specializes in regenerative medicine and dermatological therapeutics, with a focus on stem cell biology, fibroblast maturation, and tissue repair mechanisms. The lab investigates clinical applications of mesenchymal stem cell-derived conditioned media and phototherapy safety in diverse skin types, while also exploring innovative approaches in telemedicine for dermatological diagnosis. Additionally, the lab examines the biochemical and functional changes in traditional fermented foods, such as soybean paste, over extended aging periods, linking these to bioactive compounds like GABA and isoflavones. The integration of molecular biology, clinical dermatology, and biophysical material science defines the lab’s interdisciplinary approach.
Figures are computed from collected data and may differ slightly.
The application of ADSC-CM is a potential treatment option for FPHL.
Narrowband ultraviolet B (nbUVB) phototherapy is used around the world for the treatment of various skin diseases. However, the carcinogenic risk associated with nbUVB treatment in patients with skin phototypes III-V has not been studied. This retrospective study compared the incidence of skin cancer in Korean patients with skin phototypes III-V treated with nbUVB with that in a control Korean population. A total of 445 nbUVB-treated patients were followed for 1,274 person-years (mean follow-up
We evaluated the diagnostic accuracy of teleconsultations for skin diseases common in the army using a smartphone multimedia messaging service (MMS). Images of skin lesions were obtained from 100 army patients using digital cameras built into smartphones. Three remotely located dermatologists received the dermatology images and associated clinical information via the MMS. The teledermatologists' diagnoses were compared with those obtained from face-to-face examinations. The three most common dia
본 연구는 전통된장의 숙성기간에 따라 일반성분, pH, 색도, 지방산, 아미노산, γ-aminobutyric acid(GABA) 및 isoflavone의 변화에 대해 연구하였다. 실험에 사용한 전통 된장은 강원도 서원 농협에서 제조한 된장으로 숙성기간이 1, 3, 5, 7 및 10년이 경과된 된장을 사용하였으며, 대조군으로는 숙성시키지 않은 된장을 사용하였다. 일반성분 중 수분의 경우 3년째까지 일시적으로 증가하였다가 그 이후에는 감소하는 경향을 나타내었으며, pH와 색도는 숙성기간이 증가함에 따라 감소하였다. 지방산의 경우 숙성기간에 따른 유의적인 차이는 없었으나 불포화지방산의 비율이 60% 이상을 차지하였다. 아미노산 또한 유의적인 차이는 없었으나 GABA의 전구체인 glutamic acid가 숙성기간이 증가함에 따라 유의적으로 감소하는 것으로 나타났다. 대조군 시료의 경우 GABA의 함량을 분석한 결과 24.9 mg/kg이었으나, 숙성기간이 증가함에 따라 43.8, 120.6,
A new strategy for control of the in-plane orientation of pentacene is introduced using nanometer-scale periodic groove patterns as an alignment layer. Compared to pentacene films that are not aligned, an enhanced field effect mobility of 1.67 cm2 V−1 s−1 has been achieved when the optimal π-orbital overlap direction is parallel to the direction of the current flow. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2008/adma200701076_s
We found no clinical evidence to support the use of pyridoxine supplements to prevent HFS during chemotherapy.
Given that the pulse duration, fluence, and epidermal cooling were identical, the 805-nm LPDL at the three times larger spot size showed an efficacy improvement of 29.5% in axillary hair removal without serious adverse events.
The effects of tetrafluoromethane (CF4) plasma treatment of indium-tin-oxide (ITO) anode on indium diffusion into a poly(3,4-ethylene dioxythiophene):poly(styrene sulphonate) (PEDOT:PSS) layer were studied. Auger electron spectroscopy (AES) depth profile showed that 0.2at.% indium was present in the PEDOT:PSS layer when ITO was not plasma treated. The plasma treatment of ITO increased the indium concentration to ∼6at.%. The increase in indium can be explained by an oxygen deficiency in the CF4 p
The results of this cross-sectional study suggest that patients with PPP have an overlapping comorbidity profile with patients with psoriasis vulgaris but not patients with pompholyx. However, the risks of comorbidities among patients with PPP may be substantially different from those among patients with psoriasis vulgaris.
This clinical trial revealed that APHG-1001, which contains an extract of P. lobata, could prevent the development of new gray hair without any remarkable adverse effects. Thus, it can be considered as a viable treatment option for the prevention of gray hair.
In this study, cells from the stromal vascular fraction of human subcutaneous tissues were induced to differentiate toward adipose cells in vitro for 2 weeks. During adipogenic differentiation, we followed the chronological changes in their morphology with Coherent anti-Stokes Raman scattering (CARS) microscopy and checked the PPAR-γ and UCP-1 expression with RT-PCR. On day 4 after inducing adipogenic differentiation, CARS imaging showed multiple small lipid droplets (LD) distributed peripherall
This study shows that pigmentation induced by narrow-band UVB phototherapy increases continuously during the therapy and that recovery requires 10 weeks or more.
Acrodermatitis continua of Hallopeau (ACH) is a rare chronic pustular eruption that predominantly involves the fingertips. The characterization of this disease has been confused. Some have considered it as a separate entity while others as a variant of pustular psoriasis. The presented patient simultaneously had ACH and joint lesions which were diagnosed as psoriatic arthritis. We believe that because ACH may be accompanied by psoriatic arthritis, as in this case, it could be evidence that it is
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