Seung‐Baik Kang
Seoul National University 재료공학부 · 医学
Seung-Baik Kang 교수의 연구실은 관절염 치료 및 골수생물학적 복구를 중심으로 한 첨단 정형외과 연구를 수행하고 있습니다. 특히 퇴행성 관절염의 병태생리 기전을 타겟으로 한 질환수정치료제(DMOAD) 개발과 함께, 인공관절 대체재로 활용 가능한 다공성 티타늄니켈(shape memory alloy)의 생체적합성 및 뼈 치유 반응에 대한 기초 연구를 진행하고 있습니다. 또한 길이 보정 수술 및 부상 후 관절 안정화 수술 전략에 대한 임상적 연구를 병행하여 어린이 환자 대상의 기능적 회복을 목표로 하고 있습니다.
Figures are computed from collected data and may differ slightly.
Osteoarthritis (OA) is the most common form of arthritis. It is characterized by progressive destruction of articular cartilage and the development of chronic pain and constitutes a considerable socioeconomic burden. Currently, pharmacological treatments mostly aim to relieve the OA symptoms associated with inflammation and pain. However, with increasing understanding of OA pathology, several potential therapeutic targets have been identified, enabling the development of disease-modifying OA dru
Porous titanium-nickel shape memory alloys (TiNi SMA) can be fabricated using special engineering technique. This material is a whole porous material with interconnected pores. This porous TiNi SMA retains the unique properties of solid TiNi SMA. Its porosity and pore size can be controlled. Its application to orthopaedic field is very expected especially in bone substitute and bone implant and so on. The purpose of this study was to evaluate bone tissue response and histocompatibility of porous
Approximately 5 cm of lengthening and significant functional improvement can be achieved by staged reconstruction and lengthening, without major complications. Although it has limitations, this method of treatment seems to be a satisfactory surgical option for growing children with a significant leg-length discrepancy after excision of an osteosarcoma around the knee. Cite this article: <i>Bone Joint J</i> 2017;99-B:401-8.
III, Retrospective cohort study.
Osteoarthritis is a significant global health problem. Many patients seek more effective alternatives to nonsteroidal anti-inflammatory medicines or commercial supplements to manage joint pain and inflammation. FlexPro MD<sup>®</sup> (FP-MD) combines krill oil, astaxanthin, and lower molecular weight hyaluronic acid to support joint health. A 12-week, randomized, double-blind, placebo-controlled trial compared the efficacy and safety of FP-MD and placebo once daily in participants (n = 100) with
Reduction and fixation of AITFL avulsion fracture obviated the need for syndesmotic screw fixation in more than 80% of patients with AITFL avulsion fracture and syndesmotic instability.
III, Retrospective cohort study.
The purpose of this study is to investigate abnormal magnetic resonance image (MRI) findings of young active males with atraumatic anterior knee pain (AKP). Targeting young male soldiers, we prospectively gathered and analyzed 157 knee MRIs from patients with atraumatic AKP (AKP group) and 53 knee MRIs from patients without knee pain (control group). Abnormalities of the patellofemoral (PF) joint and extensor mechanism on MRI were more common in the AKP group than the control group (48% vs 13%,
Titanium–Nickel shape memory alloy (TiNi SMA) has great potential as a biomaterial in orthopaedic applications due to its unique thermal shape memory effects, superelasticity and high damping properties. We designed and manufactured bone fixaters using newly developed TiNi SMA wire (Af, 35±2°C). Two bone fixater designs (single and double ring) were prepared for the treatment of bone fracture in twenty patients (6 distal femur, 5 distal fibular, 4 distal tibia, 2 metacarpal bone, 2 periprostheti
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