名古屋大学 · 医学
Shiro Imagama教授の研究室では、神経変性疾患の病態解明を目的として、特に糖鎖（ケラタン硫酸）の神経保護的役割に注目した研究を推進しています。特に筋萎縮性側索硬化症（ALS）における細胞-autonomousおよび非細胞-autonomousな病態メカニズムの解明を進め、神経機能の維持に寄与する糖鎖の生物学的意義を解明しています。また、手術リスク要因の同定や、術中神経機能モニタリングの最適化による合併症予防にも貢献しています。
Figures are computed from collected data and may differ slightly.
The factors identified in this study should help with obtaining informed consent, surgical planning and complication prevention to reduce health care costs associated with prolonged LOS.
Biopolymers consist of three major classes, i.e., polynucleotides (DNA, RNA), polypeptides (proteins) and polysaccharides (sugar chains). It is widely accepted that polynucleotides and polypeptides play fundamental roles in the pathogenesis of neurodegenerative diseases. But, sugar chains have been poorly studied in this process, and their biological/clinical significance remains largely unexplored. Amyotrophic lateral sclerosis (ALS) is a motoneuron-degenerative disease, the pathogenesis of whi
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Age, preoperative VAs, and corrected VAs are risk factors for EO-AVFs after kyphoplasty.
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In spinal cord monitoring with intraoperative Br(E)-MsEP, an alarm point using a decrease in amplitude of ≥ 70% and delay in onset latency of ≥ 10% from baseline has high specificity that reduces false positive results.
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